Unreviewed, UniProtKB/TrEMBL Q9UGJ5 (Q9UGJ5_HUMAN)

Names and origin

Protein names

Submitted name:
    IkappaBalpha EMBL CAB65113.1

Gene names

Name:

IkBa EMBL CAB65113.1

Organism

Homo sapiens (Human) EMBL CAB65113.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	83 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321V2 Repeat RuleBase RU003536V1
Gene Ontology (GO)
Biological process	cytoplasmic sequestering of NF-kappaB Inferred from electronic annotation. Source: Compara lipopolysaccharide-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of Notch signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of myeloid cell differentiation Inferred from electronic annotation. Source: Compara nucleotide-binding oligomerization domain containing 1 signaling pathway Inferred from electronic annotation. Source: Compara nucleotide-binding oligomerization domain containing 2 signaling pathway Inferred from electronic annotation. Source: Compara protein import into nucleus, translocation Inferred from electronic annotation. Source: Compara regulation of cell proliferation Inferred from electronic annotation. Source: Compara response to exogenous dsRNA Inferred from electronic annotation. Source: Compara response to lipopolysaccharide Inferred from electronic annotation. Source: Compara response to muramyl dipeptide Inferred from electronic annotation. Source: Compara toll-like receptor 4 signaling pathway Inferred from electronic annotation. Source: Compara
Cellular component	cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular function	NF-kappaB binding Inferred from electronic annotation. Source: Compara heat shock protein binding Inferred from electronic annotation. Source: Compara protein complex binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAB65113.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UGJ5-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 37C8BEDAB8336EF0	FASTA	83	9,056
	10 20 30 40 50 60 HTCLHLASIH GYLGIVELLV SLGADVNAQE PCNGRTALHL AVDLQNPDLV SLLLKCGADV 70 80 NRVTYQGYSP YQLTWGRPST RIQ

References

[1]	"Clonal deleterious mutations in the IkappaB alpha gene in the malignant cells in Hodgkin's lymphoma." Jungnickel B., Staratschek-Jox A., Braeuninger A., Spieker T., Wolf J., Diehl V., Hansmann M.-L., Rajewsky K., Kueppers R. J. Exp. Med. 191:395-402(2000) [PubMed: 10637284] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ249290 Genomic DNA. Translation: CAB65113.1.
IPI	IPI00018330.
UniGene	Hs.81328
3D structure databases
HSSP	HSSP built from PDB template 1IKN based on UniProtKB P25963.
SMR	Q9UGJ5. Positions 1-83.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9UGJ5.
Genome annotation databases
Ensembl	ENST00000216797; ENSP00000216797; ENSG00000100906; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:7797. NFKBIA.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9UGJ5.
Gene expression databases
ArrayExpress	Q9UGJ5.
Bgee	Q9UGJ5.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR015681. NF_kB_inhbitor. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
PANTHER	PTHR18958:SF236. NF_kB_inhbitor. 1 hit.
Pfam	PF00023. Ank. 2 hits. [Graphical view]
SMART	SM00248. ANK. 2 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UGJ5_HUMAN

Accession

Primary (citable) accession number: Q9UGJ5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 19, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.