Unreviewed, UniProtKB/TrEMBL Q9UG07 (Q9UG07_HUMAN)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein DKFZp586M1622 EMBL CAB53713.1
Submitted name:
    Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b EMBL EAW78294.1

Gene names

Name:	DKFZp586M1622 EMBL CAB53713.1
Synonyms:	DVL3 EMBL EAW78294.1
ORF Names:	hCG_40299 EMBL EAW78294.1

Organism

Homo sapiens (Human) EMBL CAB53713.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PDZ (DHR) domain.

Ontologies

Gene Ontology (GO)
Biological process	intracellular signaling cascade Inferred from electronic annotation. Source: InterPro multicellular organismal development Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9UG07-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 8528BF3575F0B080	FASTA	548	59,350
	10 20 30 40 50 60 MGFVLGTQAL QCLPSWGQGW ASLVGNDCGP HRFSSSTEQS SASRLMRRHK RRRRKQKVSR 70 80 90 100 110 120 IERSSSFSSI TDSTMSLNII TVTLNMEKYN FLGISIVGQS NERGDGGIYI GSIMKGGAVA 130 140 150 160 170 180 ADGRIEPGDM LLQVNEINFE NMSNDDAVRV LREIVHKPGP ITLTVAKCWD PSPRGCFTLP 190 200 210 220 230 240 RSEPIRPIDP AAWVSHTAAM TGTFPAYGMS PSLSTITSTS SSITSSIPDT ERLDDFHLSI 250 260 270 280 290 300 HSDMAAIVKA MASPESGLEV RDRMWLKITI PNAFIGSDVV DWLYHNVEGF TDRREARKYA 310 320 330 340 350 360 SNLLKAGFIR HTVNKITFSE QCYYIFGDLC GNMANLSLHD HDGSSGASDQ DTLAPLPHPG 370 380 390 400 410 420 AAPWPMAFPY QYPPPPHPYN PHPGFPELGY SYGGGSASSQ HSEGSRSSGS NRSGSDRRKE 430 440 450 460 470 480 KDPKAGDSKS GGSGSESDHT TRSSLRGPRE RAPSERSGPA ASEHSHRSHH SLASSLRSHH 490 500 510 520 530 540 THPSYGPPGV PPLYGPPMLM MPPPPAAMGP PGAPPGRDLA SVPPELTASR QSFRMAMGNP SEFFVDVM

References

[1]	Koehrer K., Beyer A., Mewes H.W., Gassenhuber J., Wiemann S. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Uterus EMBL CAB53713.1.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL110278 mRNA. Translation: CAB53713.1. CH471052 Genomic DNA. Translation: EAW78294.1.
IPI	IPI00791929.
PIR	T14793.
UniGene	Hs.388116
3D structure databases
HSSP	HSSP built from PDB template 1L6O based on UniProtKB P51142.
SMR	Q9UG07. Positions 79-167, 238-328.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9UG07.
Proteomic databases
PRIDE	Q9UG07.
Genome annotation databases
Ensembl	ENST00000415612; ENSP00000392792; ENSG00000161202; Homo sapiens. [Genome view]
UCSC	uc003fmu.1. human.
Organism-specific databases
HGNC	HGNC:3087. DVL3.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9UG07.
Gene expression databases
ArrayExpress	Q9UG07.
Bgee	Q9UG07.
Family and domain databases
InterPro	IPR000591. DEP_dom. IPR008339. Dishevell. IPR008342. Dishevelled_3_C. IPR015506. Dsh. IPR001478. PDZ/DHR/GLGF. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
PANTHER	PTHR10878. Dsh. 1 hit.
Pfam	PF00610. DEP. 1 hit. PF00595. PDZ. 1 hit. [Graphical view]
PRINTS	PR01760. DISHEVELLED. PR01763. DISHEVELLED3.
SMART	SM00049. DEP. 1 hit. SM00228. PDZ. 1 hit. [Graphical view]
PROSITE	PS50186. DEP. 1 hit. PS50106. PDZ. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UG07_HUMAN

Accession

Primary (citable) accession number: Q9UG07

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	February 9, 2010
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.