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Protein
Submitted name:

Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b

Gene

DKFZp586M1622

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_bImported
Submitted name:
Putative uncharacterized protein DKFZp586M1622Imported
Gene namesi
Name:DKFZp586M1622Imported
Synonyms:DVL3Imported
ORF Names:hCG_40299Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

MINTiMINT-1415128.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 153PDZ (DHR)InterPro annotationAdd BLAST73
Domaini254 – 328DEPInterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiKOG3571. Eukaryota.
ENOG410Y5G4. LUCA.
HOGENOMiHOG000017084.
HOVERGENiHBG005542.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000591. DEP_dom.
IPR024580. Dishevelled_C-dom.
IPR008339. Dishevelled_fam.
IPR003351. Dishevelled_protein_dom.
IPR015506. Dsh/Dvl-rel.
IPR008342. DVL3.
IPR001478. PDZ.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR10878. PTHR10878. 1 hit.
PTHR10878:SF34. PTHR10878:SF34. 1 hit.
PfamiView protein in Pfam
PF00610. DEP. 1 hit.
PF02377. Dishevelled. 1 hit.
PF12316. Dsh_C. 1 hit.
PF00595. PDZ. 1 hit.
PRINTSiPR01760. DISHEVELLED.
PR01763. DISHEVELLED3.
SMARTiView protein in SMART
SM00049. DEP. 1 hit.
SM00228. PDZ. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF50156. SSF50156. 1 hit.
PROSITEiView protein in PROSITE
PS50186. DEP. 1 hit.
PS50106. PDZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UG07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFVLGTQAL QCLPSWGQGW ASLVGNDCGP HRFSSSTEQS SASRLMRRHK
60 70 80 90 100
RRRRKQKVSR IERSSSFSSI TDSTMSLNII TVTLNMEKYN FLGISIVGQS
110 120 130 140 150
NERGDGGIYI GSIMKGGAVA ADGRIEPGDM LLQVNEINFE NMSNDDAVRV
160 170 180 190 200
LREIVHKPGP ITLTVAKCWD PSPRGCFTLP RSEPIRPIDP AAWVSHTAAM
210 220 230 240 250
TGTFPAYGMS PSLSTITSTS SSITSSIPDT ERLDDFHLSI HSDMAAIVKA
260 270 280 290 300
MASPESGLEV RDRMWLKITI PNAFIGSDVV DWLYHNVEGF TDRREARKYA
310 320 330 340 350
SNLLKAGFIR HTVNKITFSE QCYYIFGDLC GNMANLSLHD HDGSSGASDQ
360 370 380 390 400
DTLAPLPHPG AAPWPMAFPY QYPPPPHPYN PHPGFPELGY SYGGGSASSQ
410 420 430 440 450
HSEGSRSSGS NRSGSDRRKE KDPKAGDSKS GGSGSESDHT TRSSLRGPRE
460 470 480 490 500
RAPSERSGPA ASEHSHRSHH SLASSLRSHH THPSYGPPGV PPLYGPPMLM
510 520 530 540
MPPPPAAMGP PGAPPGRDLA SVPPELTASR QSFRMAMGNP SEFFVDVM
Length:548
Mass (Da):59,350
Last modified:May 1, 2000 - v1
Checksum:i8528BF3575F0B080
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL110278 mRNA. Translation: CAB53713.1.
CH471052 Genomic DNA. Translation: EAW78294.1.
PIRiT14793.
RefSeqiXP_011510815.1. XM_011512513.2.
UniGeneiHs.388116.

Genome annotation databases

GeneIDi1857.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9UG07_HUMAN
AccessioniPrimary (citable) accession number: Q9UG07
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.