Unreviewed, UniProtKB/TrEMBL Q9UFY1 (Q9UFY1_HUMAN)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein DKFZp434N101 EMBL CAB53696.1

Gene names

Name:

DKFZp434N101 EMBL CAB53696.1

Organism

Homo sapiens (Human) EMBL CAB53696.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	629 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 C2 domain. Contains 1 PH domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain. Contains 1 SH3 domain.

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3
Molecular function	Transducer Spearmint SPM001192
Gene Ontology (GO)
Biological process	intracellular signaling cascade Inferred from electronic annotation. Source: InterPro lipid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoinositide phospholipase C activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from electronic annotation. Source: InterPro signal transducer activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAB53696.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UFY1-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 0DC47D69895BD95F	FASTA	629	71,370
	10 20 30 40 50 60 RVQQEGQTVM LGNSEFDSLV DLISYYEKHP LYRKMKLRYP INEEALEKIG TAEPDYGALY 70 80 90 100 110 120 EGRNPGFYVE ANPMPTFKCA VKALFDYKAQ REDELTFTKS AIIQNVEKQE GGWWRGDYGG 130 140 150 160 170 180 KKQLWFPSNY VEEMVNPVAL EPEREHLDEN SPLGDLLRGV LDVPACQIAI RPEGKNNRLF 190 200 210 220 230 240 VFSISMASVA HWSLDVAADS QEELQDWVKK IREVAQTADA RLTEGKIMER RKKIALELSE 250 260 270 280 290 300 LVVYCRPVPF DEEKIGTERA CYRDMSSFPE TKAEKYVNKA KGKKFLQYNR LQLSRIYPKG 310 320 330 340 350 360 QRLDSSNYDP LPMWICGSQL VALNFQTPDK PMQMNQALFM TGRHCGYVLQ PSTMRDEAFD 370 380 390 400 410 420 PFDKSSLRGL EPCAISIEVL GARHLPKNGR GIVCPFVEIE VAGAEYDSTK QKTEFVVDNG 430 440 450 460 470 480 LNPVWPAKPF HFQISNPEFA FLRFVVYEED MFSDQNFLAQ ATFPVKGLKT GYRAVPLKNN 490 500 510 520 530 540 YSEDLELASL LIKIDIFPAK QENGDLSPFS GTSLRERGSD ASGQLFHGRA REGSFESRYQ 550 560 570 580 590 600 QPFEDFRISQ EHLADHFDSR ERSKDTLPFC PGPQEGLGSM ETTASSCTPA SLESSRCCAP 610 620 CRMPRTGFFG SSPLWRPSGS RSLKPGFQQ

References

[1]	The German cDNA Consortium Poustka A., Albert R., Moosmayer P., Schupp I., Wellenreuther R., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL CAB53696.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL110247 mRNA. Translation: CAB53696.1.
IPI	IPI00745182.
PIR	T14776.
RefSeq	NP_002651.2.
UniGene	Hs.268177
3D structure databases
HSSP	HSSP built from PDB template 2PLD based on UniProtKB P08487.
SMR	Q9UFY1. Positions 1-44, 75-137, 136-218, 224-496.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9UFY1.
Genome annotation databases
GeneID	5335.
KEGG	hsa:5335.
Organism-specific databases
CTD	5335.
Phylogenomic databases
HOVERGEN	Q9UFY1.
Family and domain databases
InterPro	IPR000008. C2_Ca-dep. IPR008973. C2_Ca/lipid-bd_dom_CaLB. IPR018029. C2_membr_targeting. IPR001192. Phospholipase_C_Pinositol-sp_C. IPR001711. Phospholipase_C_Pinositol-sp_Y. IPR017946. PLC-like_Pdiesterase_TIM-brl. IPR001849. Pleckstrin_homology. IPR000980. SH2. IPR001452. SH3_domain. IPR020473. SH3_region. [Graphical view]
Gene3D	G3DSA:3.20.20.190. PLC-like_Pdiesterase_TIM-brl. 1 hit. G3DSA:3.30.505.10. SH2. 1 hit.
Pfam	PF00168. C2. 1 hit. PF00387. PI-PLC-Y. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00390. PHPHLIPASEC. PR00452. SH3DOMAIN.
SMART	SM00239. C2. 1 hit. SM00233. PH. 1 hit. SM00149. PLCYc. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
PROSITE	PS50004. C2. 1 hit. PS50003. PH_DOMAIN. 1 hit. PS50008. PIPLC_Y_DOMAIN. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UFY1_HUMAN

Accession

Primary (citable) accession number: Q9UFY1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 19, 2010
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.