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Q9UEY6 (Q9UEY6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:SLC4A2 EMBL AAF19583.2
OrganismHomo sapiens (Human) EMBL AAF19583.2
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1241 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Sequences

Sequence LengthMass (Da)Tools
Q9UEY6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D2FDA72E20D70D64

FASTA1,241136,981
        10         20         30         40         50         60 
MSSAPRRPAK GADSFCTPEP ESLGPGTPGF PEQEEDELHR TLGVERFEEI LQEAGSRGGE 

        70         80         90        100        110        120 
EPGRSYGEED FEYHRQSSHH IHHPLSTHLP PDARRRKTPQ GPGRKPRRRP GASPTGETPT 

       130        140        150        160        170        180 
IEEGEEDEDE ASEAEGARAL TQPSPVSTPS SVQFFLQEDD SADRKAERTS PSSPAPLPHQ 

       190        200        210        220        230        240 
EATPRASKGA QAGTQVEEAE AEAVAVASGT AGGDDGGASG RPLPKAQPGH RSYNLQERRR 

       250        260        270        280        290        300 
IGSMTGAEQA LLPRVPTDEI EAQTLATADL DLMKSHRFED VPGVRRHLVR KNAKGSTQSG 

       310        320        330        340        350        360 
REGREPGPTP RARPRAPHKP HEVFVELNEL LLDKNQEPQW RETARWIKFE EDVEEETERW 

       370        380        390        400        410        420 
GKPHVASLSF RSLLELRRTL AHGAVLLDLD QQTLPGVAHQ VVEQMVISDQ IKAEDRANVL 

       430        440        450        460        470        480 
RALLLKHSHP SDEKDFSFPR NISAGSLGSL LGHHHGQGAE SDPHVTEPLM GGVPETRLEV 

       490        500        510        520        530        540 
ERERDVPPPA PPAGITRSKS KHELKLLEKI PENAEATVVL VGCVEFLSRP TMAFVRLREA 

       550        560        570        580        590        600 
VELDAVLEVP VPVRFLFLLL GPSSANMDYH EIGRSISTLM SDKQFHEAAY LADEREDLLT 

       610        620        630        640        650        660 
AINAFLDCSV VLPPSEVQGE ELLRSVAHFQ RQMLKKREEQ GRLLPTGAGL EPKSAQDKAL 

       670        680        690        700        710        720 
LQMVEAAGAA EDDPLRRTGR PFGGLIRDVR RRYPHYLSDF RDALDPQCLA AVIFIYFAAL 

       730        740        750        760        770        780 
SPAITFGGLL GEKTQDLIGV SELIMSTALQ GVVFCLLGAQ PLLVIGFSGP LLVFEEAFFS 

       790        800        810        820        830        840 
FCSSNHLEYL VGRVWIGFWL VFLALLMVAL EGSFLVRFVS RFTQEIFAFL ISLIFIYETF 

       850        860        870        880        890        900 
YKLVKIFQEH PLHGCSASNS SEVDGGENMT WAGARPTLGP GNRSLAGQSG QGKPRGQPNT 

       910        920        930        940        950        960 
ALLSLVLMAG TFFIAFFLRK FKNSRFFPGR IRRVIGDFGV PIAILIMVLV DYSIEDTYTQ 

       970        980        990       1000       1010       1020 
KLSVPSGFSV TAPEKRGWVI NPLGEKSPFP VWMMVASLLP AILVFILIFM ETQITTLIIS 

      1030       1040       1050       1060       1070       1080 
KKERMLQKGS GFHLDLLLIV AMGGICALFG LPWLAAATVR SVTHANALTV MSKAVAPGDK 

      1090       1100       1110       1120       1130       1140 
PKIQEVKEQR VTGLLVALLV GLSIVIGDLL RQIPLAVLFG IFLYMGVTSL NGIQFYERLH 

      1150       1160       1170       1180       1190       1200 
LLLMPPKHHP DVTYVKKVRT LRMHLFTALQ LLCLALLWAV MSTAASLAFP FILILTVPLR 

      1210       1220       1230       1240 
MVVLTRIFTD REMKCLDANE AEPVFDEREG VDEYNEMPMP V 

« Hide

References

[1]"Molecular cloning and characterization of the human AE2 anion exchanger (SLC4A2) gene."
Medina J.F., Acin A., Prieto J.
Genomics 39:74-85(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene."
Medina J.F., Lecanda J., Acin A., Ciesielczyk P., Prieto J.
Biochem. Biophys. Res. Commun. 267:228-235(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U76669, U76667, U76668 Genomic DNA. Translation: AAF19583.2.
UniGeneHs.647069.

3D structure databases

ProteinModelPortalQ9UEY6.
SMRQ9UEY6. Positions 692-733, 1133-1165.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9UEY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG004326.

Family and domain databases

Gene3D3.40.1100.10. 1 hit.
InterProIPR001717. Anion_exchange.
IPR002978. Anion_exchange_2.
IPR018241. Anion_exchange_CS.
IPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERPTHR11453. PTHR11453. 1 hit.
PTHR11453:SF14. PTHR11453:SF14. 1 hit.
PfamPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSPR00165. ANIONEXCHNGR.
PR01188. ANIONEXHNGR2.
PR01231. HCO3TRNSPORT.
SUPFAMSSF55804. SSF55804. 2 hits.
TIGRFAMsTIGR00834. ae. 1 hit.
PROSITEPS00219. ANION_EXCHANGER_1. 1 hit.
PS00220. ANION_EXCHANGER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSLC4A2. human.

Entry information

Entry nameQ9UEY6_HUMAN
AccessionPrimary (citable) accession number: Q9UEY6
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.