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Protein
Submitted name:

Serotonin receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Serotonin receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4322HelicalSequence analysisAdd
BLAST
Transmembranei49 – 7123HelicalSequence analysisAdd
BLAST
Transmembranei196 – 21924HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSG00000166736.

Structurei

3D structure databases

ProteinModelPortaliQ9UEP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 212211Neur_chan_membInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG078855.

Family and domain databases

Gene3Di1.20.120.370. 2 hits.
InterProiIPR008132. 5HT3_rcpt.
IPR008133. 5HT3_rcpt_A.
IPR027361. Acetylcholine_rcpt_TM.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR01709. 5HT3ARECEPTR.
PR01708. 5HT3RECEPTOR.
SUPFAMiSSF90112. SSF90112. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UEP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMDIVGFYL PPNSGERVSF KITLLLGYSV FLIIVSDTLP ATAIGTPLIG
60 70 80 90 100
VYFVVCMALL VISLAETIFI VRLVHKQDLQ QPVPAWLRHL VLERIAWLLC
110 120 130 140 150
LREQSTSQRP PATSQATKTD DCSAMGNHCS HMGGPQDFEK SPRDRCSPPP
160 170 180 190 200
PPREASLAVC GLLQELSSIR QFLEKRDEIR EVARDWLRVG SVLDKLLFHI
210 220
YLLAVLAYSI TLVMLWSIWQ YA
Length:222
Mass (Da):24,978
Last modified:May 1, 2000 - v1
Checksum:iD7789067EDB4F66B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ003080 mRNA. Translation: CAA05854.1.
UniGeneiHs.413899.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ003080 mRNA. Translation: CAA05854.1.
UniGeneiHs.413899.

3D structure databases

ProteinModelPortaliQ9UEP2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG078855.

Gene expression databases

BgeeiENSG00000166736.

Family and domain databases

Gene3Di1.20.120.370. 2 hits.
InterProiIPR008132. 5HT3_rcpt.
IPR008133. 5HT3_rcpt_A.
IPR027361. Acetylcholine_rcpt_TM.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR01709. 5HT3ARECEPTR.
PR01708. 5HT3RECEPTOR.
SUPFAMiSSF90112. SSF90112. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9UEP2_HUMAN
AccessioniPrimary (citable) accession number: Q9UEP2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.