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Protein
Submitted name:

Serotonin receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Serotonin receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 43HelicalSequence analysisAdd BLAST22
Transmembranei49 – 71HelicalSequence analysisAdd BLAST23
Transmembranei196 – 219HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ9UEP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 212Neur_chan_membInterPro annotationAdd BLAST211

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG078855.

Family and domain databases

Gene3Di1.20.58.390. 1 hit.
InterProiView protein in InterPro
IPR008132. 5HT3_rcpt.
IPR008133. 5HT3_rcpt_A.
IPR006201. Neur_channel.
IPR036719. Neuro-gated_channel_TM_sf.
IPR006029. Neurotrans-gated_channel_TM.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02932. Neur_chan_memb. 1 hit.
PRINTSiPR01709. 5HT3ARECEPTR.
PR01708. 5HT3RECEPTOR.
SUPFAMiSSF90112. SSF90112. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UEP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMDIVGFYL PPNSGERVSF KITLLLGYSV FLIIVSDTLP ATAIGTPLIG
60 70 80 90 100
VYFVVCMALL VISLAETIFI VRLVHKQDLQ QPVPAWLRHL VLERIAWLLC
110 120 130 140 150
LREQSTSQRP PATSQATKTD DCSAMGNHCS HMGGPQDFEK SPRDRCSPPP
160 170 180 190 200
PPREASLAVC GLLQELSSIR QFLEKRDEIR EVARDWLRVG SVLDKLLFHI
210 220
YLLAVLAYSI TLVMLWSIWQ YA
Length:222
Mass (Da):24,978
Last modified:May 1, 2000 - v1
Checksum:iD7789067EDB4F66B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ003080 mRNA. Translation: CAA05854.1.
UniGeneiHs.413899.

Similar proteinsi

Entry informationi

Entry nameiQ9UEP2_HUMAN
AccessioniPrimary (citable) accession number: Q9UEP2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 25, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.