Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9UBX5

- FBLN5_HUMAN

UniProt

Q9UBX5 - FBLN5_HUMAN

Protein

Fibulin-5

Gene

FBLN5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 142 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling.

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. integrin binding Source: ProtInc
    3. protein binding Source: IntAct
    4. protein C-terminus binding Source: BHF-UCL

    GO - Biological processi

    1. cell-matrix adhesion Source: ProtInc
    2. elastic fiber assembly Source: BHF-UCL
    3. extracellular matrix organization Source: Reactome
    4. protein localization to cell surface Source: BHF-UCL
    5. regulation of cell growth Source: Ensembl
    6. regulation of removal of superoxide radicals Source: BHF-UCL

    Keywords - Biological processi

    Cell adhesion

    Keywords - Ligandi

    Calcium

    Enzyme and pathway databases

    ReactomeiREACT_150331. Molecules associated with elastic fibres.
    REACT_150366. Elastic fibre formation.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fibulin-5
    Short name:
    FIBL-5
    Alternative name(s):
    Developmental arteries and neural crest EGF-like protein
    Short name:
    Dance
    Urine p50 protein
    Short name:
    UP50
    Gene namesi
    Name:FBLN5
    Synonyms:DANCE
    ORF Names:UNQ184/PRO210
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 14

    Organism-specific databases

    HGNCiHGNC:3602. FBLN5.

    Subcellular locationi

    GO - Cellular componenti

    1. elastic fiber Source: Ensembl
    2. extracellular region Source: Reactome
    3. extracellular space Source: BHF-UCL
    4. extracellular vesicular exosome Source: UniProt
    5. proteinaceous extracellular matrix Source: ProtInc

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Involvement in diseasei

    Cutis laxa, autosomal dominant, 2 (ADCL2) [MIM:614434]: A connective tissue disorder characterized by loose, hyperextensible skin with decreased resilience and elasticity leading to a premature aged appearance. Face, hands, feet, joints, and torso may be differentially affected. Additional variable clinical features are gastrointestinal diverticula, hernia, and genital prolapse. Rare manifestations are pulmonary artery stenosis, aortic aneurysm, bronchiectasis, and emphysema.1 Publication
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Cutis laxa, autosomal recessive, 1A (ARCL1A) [MIM:219100]: A connective tissue disorder characterized by loose, hyperextensible skin with decreased resilience and elasticity leading to a premature aged appearance. Face, hands, feet, joints, and torso may be differentially affected. The clinical spectrum of autosomal recessive cutis laxa is highly heterogeneous with respect to organ involvement and severity. Type I autosomal recessive cutis laxa is a specific, life-threatening disorder with organ involvement, lung atelectasis and emphysema, diverticula of the gastrointestinal and genitourinary systems, and vascular anomalies. Associated cranial anomalies, late closure of the fontanel, joint laxity, hip dislocation, and inguinal hernia have been observed but are uncommon.2 Publications
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti227 – 2271S → P in ARCL1A. 2 Publications
    Corresponds to variant rs28939370 [ dbSNP | Ensembl ].
    VAR_017153
    Macular degeneration, age-related, 3 (ARMD3) [MIM:608895]: A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.1 Publication
    Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti60 – 601V → L in ARMD3. 1 Publication
    Corresponds to variant rs28939371 [ dbSNP | Ensembl ].
    VAR_019814
    Natural varianti71 – 711R → Q in ARMD3. 1 Publication
    Corresponds to variant rs28939372 [ dbSNP | Ensembl ].
    VAR_019815
    Natural varianti87 – 871P → S in ARMD3. 1 Publication
    Corresponds to variant rs28939373 [ dbSNP | Ensembl ].
    VAR_019816
    Natural varianti169 – 1691I → T in ARMD3. 1 Publication
    Corresponds to variant rs28939072 [ dbSNP | Ensembl ].
    VAR_019817
    Natural varianti351 – 3511R → W in ARMD3. 1 Publication
    Corresponds to variant rs28939073 [ dbSNP | Ensembl ].
    VAR_019818
    Natural varianti363 – 3631A → T in ARMD3. 1 Publication
    VAR_019819
    Natural varianti412 – 4121G → E in ARMD3. 1 Publication
    VAR_019820

    Keywords - Diseasei

    Age-related macular degeneration, Disease mutation

    Organism-specific databases

    MIMi219100. phenotype.
    608895. phenotype.
    614434. phenotype.
    Orphaneti279. Age-related macular degeneration.
    90348. Autosomal dominant cutis laxa.
    90349. Autosomal recessive cutis laxa type 1.
    280598. Hereditary sensorimotor neuropathy with hyperelastic skin.
    PharmGKBiPA28015.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 448425Fibulin-5PRO_0000007577Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi46 ↔ 59PROSITE-ProRule annotation
    Disulfide bondi53 ↔ 68PROSITE-ProRule annotation
    Disulfide bondi131 ↔ 144PROSITE-ProRule annotation
    Disulfide bondi138 ↔ 153PROSITE-ProRule annotation
    Disulfide bondi155 ↔ 166PROSITE-ProRule annotation
    Disulfide bondi172 ↔ 181PROSITE-ProRule annotation
    Disulfide bondi177 ↔ 190PROSITE-ProRule annotation
    Disulfide bondi192 ↔ 205PROSITE-ProRule annotation
    Disulfide bondi211 ↔ 221PROSITE-ProRule annotation
    Disulfide bondi217 ↔ 230PROSITE-ProRule annotation
    Disulfide bondi232 ↔ 245PROSITE-ProRule annotation
    Disulfide bondi251 ↔ 262PROSITE-ProRule annotation
    Disulfide bondi258 ↔ 271PROSITE-ProRule annotation
    Disulfide bondi273 ↔ 286PROSITE-ProRule annotation
    Glycosylationi283 – 2831N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi292 ↔ 305PROSITE-ProRule annotation
    Glycosylationi296 – 2961N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi299 ↔ 314PROSITE-ProRule annotation
    Disulfide bondi320 ↔ 332PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ9UBX5.
    PeptideAtlasiQ9UBX5.
    PRIDEiQ9UBX5.

    2D gel databases

    REPRODUCTION-2DPAGEIPI00294615.

    Expressioni

    Tissue specificityi

    Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes.

    Gene expression databases

    ArrayExpressiQ9UBX5.
    BgeeiQ9UBX5.
    CleanExiHS_FBLN5.
    GenevestigatoriQ9UBX5.

    Organism-specific databases

    HPAiCAB025843.
    HPA000848.
    HPA000868.

    Interactioni

    Subunit structurei

    Homodimer.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    EFEMP2O959673EBI-947897,EBI-743414
    ELNP155023EBI-947897,EBI-1222108
    FBN1P355553EBI-947897,EBI-2505934
    LTBP2Q147672EBI-947897,EBI-1546118

    Protein-protein interaction databases

    BioGridi115771. 7 interactions.
    IntActiQ9UBX5. 16 interactions.
    MINTiMINT-2868380.
    STRINGi9606.ENSP00000345008.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UBX5.
    SMRiQ9UBX5. Positions 21-327.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini42 – 8241EGF-like 1; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini127 – 16741EGF-like 2; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini168 – 20639EGF-like 3; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini207 – 24640EGF-like 4; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini247 – 28741EGF-like 5; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST
    Domaini288 – 33346EGF-like 6; calcium-bindingPROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi54 – 563Cell attachment siteSequence Analysis

    Sequence similaritiesi

    Belongs to the fibulin family.Curated
    Contains 6 EGF-like domains.PROSITE-ProRule annotation

    Keywords - Domaini

    EGF-like domain, Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG309650.
    HOGENOMiHOG000234337.
    HOVERGENiHBG051560.
    KOiK17340.
    PhylomeDBiQ9UBX5.
    TreeFamiTF317514.

    Family and domain databases

    InterProiIPR026823. cEGF.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view]
    PfamiPF12662. cEGF. 1 hit.
    PF07645. EGF_CA. 3 hits.
    [Graphical view]
    SMARTiSM00179. EGF_CA. 4 hits.
    [Graphical view]
    SUPFAMiSSF57184. SSF57184. 3 hits.
    PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
    PS01186. EGF_2. 4 hits.
    PS50026. EGF_3. 5 hits.
    PS01187. EGF_CA. 6 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9UBX5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP    50
    EACRGDMMCV NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG PYPAAAPPLS 100
    APNYPTISRP LICRFGYQMD ESNQCVDVDE CATDSHQCNP TQICINTEGG 150
    YTCSCTDGYW LLEGQCLDID ECRYGYCQQL CANVPGSYSC TCNPGFTLNE 200
    DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELEE DGVHCSDMDE 250
    CSFSEFLCQH ECVNQPGTYF CSCPPGYILL DDNRSCQDIN ECEHRNHTCN 300
    LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY 350
    RDMDVVSGRS VPADIFQMQA TTRYPGAYYI FQIKSGNEGR EFYMRQTGPI 400
    SATLVMTRPI KGPREIQLDL EMITVNTVIN FRGSSVIRLR IYVSQYPF 448
    Length:448
    Mass (Da):50,180
    Last modified:May 1, 2000 - v1
    Checksum:i19FCA51FDA328003
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti69 – 702IP → HS in AAC62107. 1 PublicationCurated
    Sequence conflicti147 – 1482TE → MK in AAC62107. 1 PublicationCurated
    Sequence conflicti228 – 2281F → L in AAQ89257. (PubMed:12975309)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti60 – 601V → L in ARMD3. 1 Publication
    Corresponds to variant rs28939371 [ dbSNP | Ensembl ].
    VAR_019814
    Natural varianti71 – 711R → Q in ARMD3. 1 Publication
    Corresponds to variant rs28939372 [ dbSNP | Ensembl ].
    VAR_019815
    Natural varianti87 – 871P → S in ARMD3. 1 Publication
    Corresponds to variant rs28939373 [ dbSNP | Ensembl ].
    VAR_019816
    Natural varianti169 – 1691I → T in ARMD3. 1 Publication
    Corresponds to variant rs28939072 [ dbSNP | Ensembl ].
    VAR_019817
    Natural varianti227 – 2271S → P in ARCL1A. 2 Publications
    Corresponds to variant rs28939370 [ dbSNP | Ensembl ].
    VAR_017153
    Natural varianti351 – 3511R → W in ARMD3. 1 Publication
    Corresponds to variant rs28939073 [ dbSNP | Ensembl ].
    VAR_019818
    Natural varianti363 – 3631A → T in ARMD3. 1 Publication
    VAR_019819
    Natural varianti364 – 3641D → Y.
    Corresponds to variant rs1802492 [ dbSNP | Ensembl ].
    VAR_026986
    Natural varianti412 – 4121G → E in ARMD3. 1 Publication
    VAR_019820

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ133490 mRNA. Translation: CAB38568.1.
    AF112152 mRNA. Translation: AAD41768.1.
    AF093118 mRNA. Translation: AAC62107.1.
    AY358898 mRNA. Translation: AAQ89257.1.
    CR457140 mRNA. Translation: CAG33421.1.
    AK075147 mRNA. Translation: BAG52073.1.
    CH471061 Genomic DNA. Translation: EAW81466.1.
    BC022280 mRNA. Translation: AAH22280.1.
    CCDSiCCDS9898.1.
    RefSeqiNP_006320.2. NM_006329.3.
    UniGeneiHs.332708.

    Genome annotation databases

    EnsembliENST00000342058; ENSP00000345008; ENSG00000140092.
    GeneIDi10516.
    KEGGihsa:10516.
    UCSCiuc001xzx.4. human.

    Polymorphism databases

    DMDMi12643876.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ133490 mRNA. Translation: CAB38568.1 .
    AF112152 mRNA. Translation: AAD41768.1 .
    AF093118 mRNA. Translation: AAC62107.1 .
    AY358898 mRNA. Translation: AAQ89257.1 .
    CR457140 mRNA. Translation: CAG33421.1 .
    AK075147 mRNA. Translation: BAG52073.1 .
    CH471061 Genomic DNA. Translation: EAW81466.1 .
    BC022280 mRNA. Translation: AAH22280.1 .
    CCDSi CCDS9898.1.
    RefSeqi NP_006320.2. NM_006329.3.
    UniGenei Hs.332708.

    3D structure databases

    ProteinModelPortali Q9UBX5.
    SMRi Q9UBX5. Positions 21-327.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 115771. 7 interactions.
    IntActi Q9UBX5. 16 interactions.
    MINTi MINT-2868380.
    STRINGi 9606.ENSP00000345008.

    Polymorphism databases

    DMDMi 12643876.

    2D gel databases

    REPRODUCTION-2DPAGE IPI00294615.

    Proteomic databases

    PaxDbi Q9UBX5.
    PeptideAtlasi Q9UBX5.
    PRIDEi Q9UBX5.

    Protocols and materials databases

    DNASUi 10516.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000342058 ; ENSP00000345008 ; ENSG00000140092 .
    GeneIDi 10516.
    KEGGi hsa:10516.
    UCSCi uc001xzx.4. human.

    Organism-specific databases

    CTDi 10516.
    GeneCardsi GC14M092335.
    GeneReviewsi FBLN5.
    HGNCi HGNC:3602. FBLN5.
    HPAi CAB025843.
    HPA000848.
    HPA000868.
    MIMi 219100. phenotype.
    604580. gene.
    608895. phenotype.
    614434. phenotype.
    neXtProti NX_Q9UBX5.
    Orphaneti 279. Age-related macular degeneration.
    90348. Autosomal dominant cutis laxa.
    90349. Autosomal recessive cutis laxa type 1.
    280598. Hereditary sensorimotor neuropathy with hyperelastic skin.
    PharmGKBi PA28015.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG309650.
    HOGENOMi HOG000234337.
    HOVERGENi HBG051560.
    KOi K17340.
    PhylomeDBi Q9UBX5.
    TreeFami TF317514.

    Enzyme and pathway databases

    Reactomei REACT_150331. Molecules associated with elastic fibres.
    REACT_150366. Elastic fibre formation.

    Miscellaneous databases

    GeneWikii FBLN5.
    GenomeRNAii 10516.
    NextBioi 39880.
    PROi Q9UBX5.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9UBX5.
    Bgeei Q9UBX5.
    CleanExi HS_FBLN5.
    Genevestigatori Q9UBX5.

    Family and domain databases

    InterProi IPR026823. cEGF.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view ]
    Pfami PF12662. cEGF. 1 hit.
    PF07645. EGF_CA. 3 hits.
    [Graphical view ]
    SMARTi SM00179. EGF_CA. 4 hits.
    [Graphical view ]
    SUPFAMi SSF57184. SSF57184. 3 hits.
    PROSITEi PS00010. ASX_HYDROXYL. 4 hits.
    PS01186. EGF_2. 4 hits.
    PS50026. EGF_3. 5 hits.
    PS01187. EGF_CA. 6 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Kostka G.
      Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Melanoma.
    2. "DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries."
      Nakamura T., Ruiz-Lozano P., Lindner V., Yabe D., Taniwaki M., Furukawa Y., Kobuke K., Tashiro K., Lu Z., Andon N.L., Schaub R., Matsumori A., Sasayama S., Chien K.R., Honjo T.
      J. Biol. Chem. 274:22476-22483(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    3. Zemel R., Sholto O., Shaul Y.
      Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Urine.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    5. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    6. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.
      , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
      DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Placenta.
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Lung.
    9. Cited for: SUBUNIT.
    10. "Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa."
      Loeys B., van Maldergem L., Mortier G., Coucke P., Gerniers S., Naeyaert J.-M., de Paepe A.
      Hum. Mol. Genet. 11:2113-2118(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANT ARCL1A PRO-227.
    11. "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene."
      Markova D., Zou Y., Ringpfeil F., Sasaki T., Kostka G., Timpl R., Uitto J., Chu M.-L.
      Am. J. Hum. Genet. 72:998-1004(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INVOLVEMENT IN ADCL2.
    12. Cited for: VARIANTS ARMD3 LEU-60; GLN-71; SER-87; THR-169; TRP-351; THR-363 AND GLU-412.
    13. "Homozygous missense mutation in fibulin-5 in an Iranian autosomal recessive cutis laxa pedigree and associated haplotype."
      Elahi E., Kalhor R., Banihosseini S.S., Torabi N., Pour-Jafari H., Houshmand M., Amini S.S.H., Ramezani A., Loeys B.
      J. Invest. Dermatol. 126:1506-1509(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANT ARCL1A PRO-227.

    Entry informationi

    Entry nameiFBLN5_HUMAN
    AccessioniPrimary (citable) accession number: Q9UBX5
    Secondary accession number(s): O75966, Q6IAL4, Q6UWA3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 142 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 14
      Human chromosome 14: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3