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Protein
Submitted name:

Antithrombin III

Gene

AT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Antithrombin IIIImported
Submitted name:
Antithrombin III gene 3' (aa 375-432)Imported
Gene namesi
Name:AT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9UBW9.

Expressioni

Gene expression databases

BgeeiQ9UBW9.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ9UBW9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family.UniRule annotation

Family and domain databases

InterProiIPR015555. AT-III.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PTHR11461:SF53. PTHR11461:SF53. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UBW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VNEEGSEAAA STAVVIAGRS LNPNRVTFKA NRPFLVFIRE VPLNTIIFMG

RVANPCVK
Length:58
Mass (Da):6,286
Last modified:May 1, 2000 - v1
Checksum:i1F2FCCB302E643A3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M21645 Genomic DNA. Translation: AAA51795.1.
X03204 Genomic DNA. Translation: CAA26952.1.
UniGeneiHs.75599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M21645 Genomic DNA. Translation: AAA51795.1.
X03204 Genomic DNA. Translation: CAA26952.1.
UniGeneiHs.75599.

3D structure databases

ProteinModelPortaliQ9UBW9.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ9UBW9.

Proteomic databases

PRIDEiQ9UBW9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ9UBW9.

Family and domain databases

InterProiIPR015555. AT-III.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PTHR11461:SF53. PTHR11461:SF53. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Location of two of the introns in the antithrombin-III gene."
    Jagd S., Vibe-Pedersen K., Magnusson S.
    FEBS Lett. 193:213-216(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Antithrombin III Utah: proline-407 to leucine mutation in a highly conserved region near the inhibitor reactive site."
    Bock S.C., Marrinan J.A., Radziejewska E.
    Biochemistry 27:6171-6178(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UBW9_HUMAN
AccessioniPrimary (citable) accession number: Q9UBW9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.