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Q9UBT9

- Q9UBT9_HUMAN

UniProt

Q9UBT9 - Q9UBT9_HUMAN

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Protein
Submitted name:

C-C chemokine receptor 5

Gene
CCR5
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. C-C chemokine receptor activity Source: InterPro

GO - Biological processi

  1. chemotaxis Source: InterPro
  2. immune response Source: InterPro
  3. inflammatory response Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotations, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
C-C chemokine receptor 5Imported
Gene namesi
Name:CCR5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

ArrayExpressiQ9UBT9.
BgeeiQ9UBT9.

Structurei

3D structure databases

ProteinModelPortaliQ9UBT9.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG106917.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR002240. Chemokine_CCR5.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24227. PTHR24227. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01110. CHEMOKINER5.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UBT9-1 [UniParc]FASTAAdd to Basket

« Hide

PIYDINYYTS EPCQKINVKQ IAARLLPPLY SLVFIFGFVG NMLVILILIN    50
CKRLKSMTDI YLLNLAISDL FFLLTVPFWA HYAAAQWDFG NTMCQLLTGL 100
YFIGFFSGIF FIILLTIDRY LAVVHAVFAL KARTVTFGVV TSVITWVVAV 150
FASLPGIIFT RSQKEGLHYT CSSHFPYSQY QFWKNFQTLK IVILGLVLPL 200
LVMVICYSGI LKTLLRCRNE KKRHRAVRLI FTIMIVYFLF WAPYNIVLLL 250
NTFQEFFGLN NCSSSNRLDQ AMQVTETLGM THCCINPIIY AFVGEKFRNY 300
LLVFFQKHIA KRFCKCCSIF QQEAPERASS VYTRSTGEQ 339
Length:339
Mass (Da):39,114
Last modified:May 1, 2000 - v1
Checksum:i3C6369F92C29F4A7
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei339 – 3391Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF161909 Genomic DNA. Translation: AAD47666.1.
AF161910 Genomic DNA. Translation: AAD47667.1.
AF161911 Genomic DNA. Translation: AAD47668.1.
AF161912 Genomic DNA. Translation: AAD47669.1.
AF161915 Genomic DNA. Translation: AAD47672.1.
UniGeneiHs.450802.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF161909 Genomic DNA. Translation: AAD47666.1 .
AF161910 Genomic DNA. Translation: AAD47667.1 .
AF161911 Genomic DNA. Translation: AAD47668.1 .
AF161912 Genomic DNA. Translation: AAD47669.1 .
AF161915 Genomic DNA. Translation: AAD47672.1 .
UniGenei Hs.450802.

3D structure databases

ProteinModelPortali Q9UBT9.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG106917.

Gene expression databases

ArrayExpressi Q9UBT9.
Bgeei Q9UBT9.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR002240. Chemokine_CCR5.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
PANTHERi PTHR24227. PTHR24227. 1 hit.
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00657. CCCHEMOKINER.
PR01110. CHEMOKINER5.
PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequences of the CCR5 genes from diverse simian and prosimian species."
    Kunstman K., Chen Z., Korber B., Oprondek J., Stanton J., Agy M., Shibata R., Yoder A., Pillai S., Kuiken C., Marx P., Wolinksy S.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Structure and function of CC-chemokine receptor 5 homologues derived from representative primate species and subspecies of the taxonomic suborders Prosimii and Anthropoidea."
    Kunstman K.J., Puffer B., Korber B.T., Kuiken C., Smith U.R., Kunstman J., Stanton J., Agy M., Shibata R., Yoder A.D., Pillai S., Doms R.W., Marx P., Wolinsky S.M.
    J. Virol. 77:12310-12318(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UBT9_HUMAN
AccessioniPrimary (citable) accession number: Q9UBT9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 3, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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