ID   Q9UBT1_HUMAN            Unreviewed;        23 AA.
AC   Q9UBT1;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   13-SEP-2023, entry version 103.
DE   SubName: Full=Estrogen receptor {ECO:0000313|EMBL:AAC51875.1};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAC51875.1};
RN   [1] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=3754034; DOI=10.1038/320134a0;
RA   Green S., Walter P., Kumar V., Krust A., Bornert J.M., Argos P.,
RA   Chambon P.;
RT   "Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-
RT   A.";
RL   Nature 320:134-139(1986).
RN   [2] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=3753802; DOI=10.1126/science.3753802;
RA   Greene G.L., Gilna P., Waterfield M., Baker A., Hort Y., Shine J.;
RT   "Sequence and expression of human estrogen receptor complementary DNA.";
RL   Science 231:1150-1154(1986).
RN   [3] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=2015052;
RA   Keaveney M., Klug J., Dawson M.T., Nestor P.V., Neilan J.G., Forde R.C.,
RA   Gannon F.;
RT   "Evidence for a previously unidentified upstream exon in the human
RT   oestrogen receptor gene.";
RL   J. Mol. Endocrinol. 6:111-115(1991).
RN   [4] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=1567414; DOI=10.1016/S0006-291X(05)80289-X;
RA   Piva R., Gambari R., Zorzato F., Kumar L., del Senno L.;
RT   "Analysis of upstream sequences of the human estrogen receptor gene.";
RL   Biochem. Biophys. Res. Commun. 183:996-1002(1992).
RN   [5] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=1476547;
RA   Keaveney M., Klug J., Gannon F.;
RT   "Sequence analysis of the 5' flanking region of the human estrogen receptor
RT   gene.";
RL   DNA Seq. 2:347-358(1992).
RN   [6] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=8240974; DOI=10.1016/0960-0760(93)90179-Z;
RA   Piva R., Bianchi N., Aguiari G.L., Gambari R., del Senno L.;
RT   "Sequencing of an RNA transcript of the human estrogen receptor gene:
RT   evidence for a new transcriptional event.";
RL   J. Steroid Biochem. Mol. Biol. 46:531-538(1993).
RN   [7] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE OF 1-17.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=8647321; DOI=10.1016/0303-7207(95)03716-0;
RA   Grandien K.;
RT   "Determination of transcription start sites in the human estrogen receptor
RT   gene and identification of a novel, tissue-specific, estrogen receptor-mRNA
RT   isoform.";
RL   Mol. Cell. Endocrinol. 116:207-212(1996).
RN   [8] {ECO:0000313|EMBL:AAC51875.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Breast adenocarcinoma {ECO:0000313|EMBL:AAC51875.1};
RX   PubMed=9393949; DOI=10.1016/S0960-0760(97)00029-0;
RA   Thompson D.A., McPherson L.A., Carmeci C., deConinck E.C., Weigel R.J.;
RT   "Identification of two estrogen receptor transcripts with novel 5' exons
RT   isolated from a MCF7 cDNA library.";
RL   J. Steroid Biochem. Mol. Biol. 62:143-153(1997).
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DR   EMBL; U68067; AAC51874.1; -; mRNA.
DR   EMBL; U68068; AAC51875.1; -; mRNA.
DR   RefSeq; NP_001116212.1; NM_001122740.1.
DR   AlphaFoldDB; Q9UBT1; -.
DR   DNASU; 2099; -.
DR   GeneID; 2099; -.
DR   CTD; 2099; -.
DR   PharmGKB; PA156; -.
DR   BioGRID-ORCS; 2099; 29 hits in 1184 CRISPR screens.
DR   GenomeRNAi; 2099; -.
PE   2: Evidence at transcript level;
KW   Receptor {ECO:0000313|EMBL:AAC51875.1}.
FT   NON_TER         23
FT                   /evidence="ECO:0000313|EMBL:AAC51875.1"
SQ   SEQUENCE   23 AA;  2526 MW;  4A678094301081FD CRC64;
     MTMTLHTKAS GMALLHQIQG NEL
//