Q9UBT1 (Q9UBT1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Estrogen receptor EMBL AAC51875.1
Organism	Homo sapiens (Human) EMBL AAC51875.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	23 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL AAC51875.1
Gene Ontology (GO)
Biological_process	androgen metabolic process Inferred from electronic annotation. Source: Compara antral ovarian follicle growth Inferred from electronic annotation. Source: Compara cellular response to estrogen stimulus Inferred from electronic annotation. Source: Compara epithelial cell development Inferred from electronic annotation. Source: Compara epithelial cell proliferation involved in mammary gland duct elongation Inferred from electronic annotation. Source: Compara intracellular receptor mediated signaling pathway Inferred from electronic annotation. Source: GOC male gonad development Inferred from electronic annotation. Source: Compara mammary gland alveolus development Inferred from electronic annotation. Source: Compara mammary gland branching involved in pregnancy Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Inferred from electronic annotation. Source: Compara prostate epithelial cord elongation Inferred from electronic annotation. Source: Compara regulation of apoptotic process Inferred from electronic annotation. Source: Compara regulation of branching involved in prostate gland morphogenesis Inferred from electronic annotation. Source: Compara uterus development Inferred from electronic annotation. Source: Compara vagina development Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	chromatin binding Inferred from electronic annotation. Source: Compara ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	23	1	EMBL AAC51875.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UBT1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 4A678094301081FD	FASTA	23	2,526
	10 20 MTMTLHTKAS GMALLHQIQG NEL

References

[1]	"Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A." Green S., Walter P., Kumar V., Krust A., Bornert J.-M., Argos P., Chambon P. Nature 320:134-139(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[2]	"Sequence and expression of human estrogen receptor complementary DNA." Greene G.L., Gilna P., Waterfield M., Baker A., Hort Y., Shine J. Science 231:1150-1154(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[3]	"Evidence for a previously unidentified upstream exon in the human oestrogen receptor gene." Keaveney M., Klug J., Dawson M.T., Nestor P.V., Neilan J.G., Forde R.C., Gannon F. J. Mol. Endocrinol. 6:111-115(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[4]	"Analysis of upstream sequences of the human estrogen receptor gene." Piva R., Gambari R., Zorzato F., Kumar L., del Senno L. Biochem. Biophys. Res. Commun. 183:996-1002(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[5]	"Sequence analysis of the 5' flanking region of the human estrogen receptor gene." Keaveney M., Klug J., Gannon F. DNA Seq. 2:347-358(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[6]	"Sequencing of an RNA transcript of the human estrogen receptor gene: evidence for a new transcriptional event." Piva R., Bianchi N., Aguiari G.L., Gambari R., del Senno L. J. Steroid Biochem. Mol. Biol. 46:531-538(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[7]	"Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor-mRNA isoform." Grandien K. Mol. Cell. Endocrinol. 116:207-212(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE OF 1-17. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
[8]	"Identification of two estrogen receptor transcripts with novel 5' exons isolated from a MCF7 cDNA library." Thompson D.A., McPherson L.A., Carmeci C., deConinck E.C., Weigel R.J. J. Steroid Biochem. Mol. Biol. 62:143-153(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast adenocarcinoma EMBL AAC51875.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U68067 mRNA. Translation: AAC51874.1. U68068 mRNA. Translation: AAC51875.1.
IPI	IPI00879773.
RefSeq	NP_001116212.1. NM_001122740.1.
UniGene	Hs.208124.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9UBT1.
Protocols and materials databases
DNASU	2099.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2099.
KEGG	hsa:2099.
Organism-specific databases
CTD	2099.
PharmGKB	PA156.
Phylogenomic databases
KO	K08550.
Gene expression databases
ArrayExpress	Q9UBT1.
Bgee	Q9UBT1.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	2099.
NextBio	8491.

Entry information

Entry name

Q9UBT1_HUMAN

Accession

Primary (citable) accession number: Q9UBT1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	April 3, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.