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Q9UBT1

- Q9UBT1_HUMAN

UniProt

Q9UBT1 - Q9UBT1_HUMAN

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Protein
Submitted name:

Estrogen receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: Ensembl
  2. ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Source: Ensembl

GO - Biological processi

  1. androgen metabolic process Source: Ensembl
  2. antral ovarian follicle growth Source: Ensembl
  3. cellular response to estrogen stimulus Source: Ensembl
  4. epithelial cell development Source: Ensembl
  5. epithelial cell proliferation involved in mammary gland duct elongation Source: Ensembl
  6. male gonad development Source: Ensembl
  7. mammary gland alveolus development Source: Ensembl
  8. mammary gland branching involved in pregnancy Source: Ensembl
  9. positive regulation of fibroblast proliferation Source: Ensembl
  10. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  11. prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Source: Ensembl
  12. prostate epithelial cord elongation Source: Ensembl
  13. regulation of apoptotic process Source: Ensembl
  14. regulation of branching involved in prostate gland morphogenesis Source: Ensembl
  15. uterus development Source: Ensembl
  16. vagina development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Estrogen receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA156.

Expressioni

Gene expression databases

ExpressionAtlasiQ9UBT1. baseline and differential.

Family & Domainsi

Phylogenomic databases

KOiK08550.

Sequencei

Sequence statusi: Fragment.

Q9UBT1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20 
MTMTLHTKAS GMALLHQIQG NEL
Length:23
Mass (Da):2,526
Last modified:May 1, 2000 - v1
Checksum:i4A678094301081FD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei23 – 231Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68067 mRNA. Translation: AAC51874.1.
U68068 mRNA. Translation: AAC51875.1.
RefSeqiNP_001116212.1. NM_001122740.1.
UniGeneiHs.208124.
Hs.744830.

Genome annotation databases

GeneIDi2099.
KEGGihsa:2099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68067 mRNA. Translation: AAC51874.1 .
U68068 mRNA. Translation: AAC51875.1 .
RefSeqi NP_001116212.1. NM_001122740.1.
UniGenei Hs.208124.
Hs.744830.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 2099.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2099.
KEGGi hsa:2099.

Organism-specific databases

CTDi 2099.
PharmGKBi PA156.

Phylogenomic databases

KOi K08550.

Miscellaneous databases

GenomeRNAii 2099.
NextBioi 8491.

Gene expression databases

ExpressionAtlasi Q9UBT1. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A."
    Green S., Walter P., Kumar V., Krust A., Bornert J.M., Argos P., Chambon P.
    Nature 320:134-139(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  2. "Sequence and expression of human estrogen receptor complementary DNA."
    Greene G.L., Gilna P., Waterfield M., Baker A., Hort Y., Shine J.
    Science 231:1150-1154(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  3. "Evidence for a previously unidentified upstream exon in the human oestrogen receptor gene."
    Keaveney M., Klug J., Dawson M.T., Nestor P.V., Neilan J.G., Forde R.C., Gannon F.
    J. Mol. Endocrinol. 6:111-115(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  4. "Analysis of upstream sequences of the human estrogen receptor gene."
    Piva R., Gambari R., Zorzato F., Kumar L., del Senno L.
    Biochem. Biophys. Res. Commun. 183:996-1002(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  5. "Sequence analysis of the 5' flanking region of the human estrogen receptor gene."
    Keaveney M., Klug J., Gannon F.
    DNA Seq. 2:347-358(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  6. "Sequencing of an RNA transcript of the human estrogen receptor gene: evidence for a new transcriptional event."
    Piva R., Bianchi N., Aguiari G.L., Gambari R., del Senno L.
    J. Steroid Biochem. Mol. Biol. 46:531-538(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  7. "Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor-mRNA isoform."
    Grandien K.
    Mol. Cell. Endocrinol. 116:207-212(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 1-17.
    Tissue: Breast adenocarcinomaImported.
  8. "Identification of two estrogen receptor transcripts with novel 5' exons isolated from a MCF7 cDNA library."
    Thompson D.A., McPherson L.A., Carmeci C., deConinck E.C., Weigel R.J.
    J. Steroid Biochem. Mol. Biol. 62:143-153(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Breast adenocarcinomaImported.

Entry informationi

Entry nameiQ9UBT1_HUMAN
AccessioniPrimary (citable) accession number: Q9UBT1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.