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Q9UBS9

- SUCO_HUMAN

UniProt

Q9UBS9 - SUCO_HUMAN

Protein

SUN domain-containing ossification factor

Gene

SUCO

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation By similarity.By similarity

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. ossification Source: UniProtKB-KW
    3. positive regulation of collagen biosynthetic process Source: UniProtKB
    4. positive regulation of osteoblast differentiation Source: UniProtKB
    5. regulation of bone remodeling Source: UniProtKB

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Osteogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SUN domain-containing ossification factor
    Alternative name(s):
    Membrane protein CH1
    Protein osteopotentia homolog
    SUN-like protein 1
    Gene namesi
    Name:SUCO
    Synonyms:C1orf9, CH1, OPT, SLP1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:1240. SUCO.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. membrane Source: UniProtKB
    3. rough endoplasmic reticulum Source: UniProtKB
    4. rough endoplasmic reticulum membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA25621.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2929Sequence AnalysisAdd
    BLAST
    Chaini30 – 12541225SUN domain-containing ossification factorPRO_5000065707Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi236 – 2361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi524 – 5241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi928 – 9281N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi955 – 9551N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiQ9UBS9.
    PaxDbiQ9UBS9.
    PRIDEiQ9UBS9.

    Expressioni

    Tissue specificityi

    Highly expressed in pancreas and testis and to a lower extent in prostate, ovary, heart, thymus, small intestine and spleen.1 Publication

    Gene expression databases

    ArrayExpressiQ9UBS9.
    BgeeiQ9UBS9.
    CleanExiHS_C1orf9.
    GenevestigatoriQ9UBS9.

    Organism-specific databases

    HPAiHPA047251.

    Interactioni

    Protein-protein interaction databases

    BioGridi119536. 2 interactions.
    STRINGi9606.ENSP00000263688.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UBS9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1011 – 103121HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini284 – 453170SUNPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili909 – 1009101Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SUN domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG314762.
    HOGENOMiHOG000070169.
    HOVERGENiHBG107549.
    PhylomeDBiQ9UBS9.
    TreeFamiTF105817.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    InterProiIPR008979. Galactose-bd-like.
    IPR012919. Sad1_UNC_C.
    [Graphical view]
    PfamiPF07738. Sad1_UNC. 1 hit.
    [Graphical view]
    SUPFAMiSSF49785. SSF49785. 1 hit.
    PROSITEiPS51469. SUN. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9UBS9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKKHRRALAL VSCLFLCSLV WLPSWRVCCK ESSSASASSY YSQDDNCALE     50
    NEDVQFQKKD EREGPINAES LGKSGSNLPI SPKEHKLKDD SIVDVQNTES 100
    KKLSPPVVET LPTVDLHEES SNAVVDSETV ENISSSSTSE ITPISKLDEI 150
    EKSGTIPIAK PSETEQSETD CDVGEALDAS APIEQPSFVS PPDSLVGQHI 200
    ENVSSSHGKG KITKSEFESK VSASEQGGGD PKSALNASDN LKNESSDYTK 250
    PGDIDPTSVA SPKDPEDIPT FDEWKKKVME VEKEKSQSMH ASSNGGSHAT 300
    KKVQKNRNNY ASVECGAKIL AANPEAKSTS AILIENMDLY MLNPCSTKIW 350
    FVIELCEPIQ VKQLDIANYE LFSSTPKDFL VSISDRYPTN KWIKLGTFHG 400
    RDERNVQSFP LDEQMYAKYV KMFIKYIKVE LLSHFGSEHF CPLSLIRVFG 450
    TSMVEEYEEI ADSQYHSERQ ELFDEDYDYP LDYNTGEDKS SKNLLGSATN 500
    AILNMVNIAA NILGAKTEDL TEGNKSISEN ATATAAPKMP ESTPVSTPVP 550
    SPEYVTTEVH THDMEPSTPD TPKESPIVQL VQEEEEEASP STVTLLGSGE 600
    QEDESSPWFE SETQIFCSEL TTICCISSFS EYIYKWCSVR VALYRQRSRT 650
    ALSKGKDYLV LAQPPLLLPA ESVDVSVLQP LSGELENTNI EREAETVVLG 700
    DLSSSMHQDD LVNHTVDAVE LEPSHSQTLS QSLLLDITPE INPLPKIEVS 750
    ESVEYEAGHI PSPVIPQESS VEIDNETEQK SESFSSIEKP SITYETNKVN 800
    ELMDNIIKED VNSMQIFTKL SETIVPPINT ATVPDNEDGE AKMNIADTAK 850
    QTLISVVDSS SLPEVKEEEQ SPEDALLRGL QRTATDFYAE LQNSTDLGYA 900
    NGNLVHGSNQ KESVFMRLNN RIKALEVNMS LSGRYLEELS QRYRKQMEEM 950
    QKAFNKTIVK LQNTSRIAEE QDQRQTEAIQ LLQAQLTNMT QLVSNLSATV 1000
    AELKREVSDR QSYLVISLVL CVVLGLMLCM QRCRNTSQFD GDYISKLPKS 1050
    NQYPSPKRCF SSYDDMNLKR RTSFPLMRSK SLQLTGKEVD PNDLYIVEPL 1100
    KFSPEKKKKR CKYKIEKIET IKPEEPLHPI ANGDIKGRKP FTNQRDFSNM 1150
    GEVYHSSYKG PPSEGSSETS SQSEESYFCG ISACTSLCNG QSQKTKTEKR 1200
    ALKRRRSKVQ DQGKLIKTLI QTKSGSLPSL HDIIKGNKEI TVGTFGVTAV 1250
    SGHI 1254
    Length:1,254
    Mass (Da):139,430
    Last modified:May 1, 2000 - v1
    Checksum:i4EBA1ABCC27DAAB1
    GO
    Isoform 2 (identifier: Q9UBS9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MRGFLARPFL...SGRGKKEEKM
         60-96: Missing.
         421-427: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,405
    Mass (Da):156,418
    Checksum:iFA5EB6BA78F4A6DD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti452 – 4521S → N in AAF04619. 1 PublicationCurated
    Sequence conflicti811 – 8111V → M in AAF04619. 1 PublicationCurated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 11M → MRGFLARPFLSTNQHLAQWG SPLPQGKGLVQLPSQHTRHS RPFHELCSKEENSATVPKLI SLVVSSETIDFSNKTMDSRR DWEREKRILEGKLQLPKALA RTQRARDEGRAWTSRWLQRR RSPESCEAPLSAPLWGPQRG LPGREPLRSRSASAIALRTI GHILALLLRLLHLGLGSGGC REDVPPSGRGKKEEKM in isoform 2. 1 PublicationVSP_027921
    Alternative sequencei60 – 9637Missing in isoform 2. 1 PublicationVSP_027922Add
    BLAST
    Alternative sequencei421 – 4277Missing in isoform 2. 1 PublicationVSP_027923

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ250075 mRNA. Translation: CAB57360.1.
    AF097535 mRNA. Translation: AAF04619.1.
    AL035291 mRNA. Translation: CAA22894.1.
    Z96050, Z94054 Genomic DNA. Translation: CAI19034.1.
    Z94054, Z96050 Genomic DNA. Translation: CAI19460.1.
    BC137125 mRNA. Translation: AAI37126.1.
    CH471067 Genomic DNA. Translation: EAW90931.1.
    AF310265 Genomic DNA. Translation: AAK28742.1.
    AF310266 Genomic DNA. Translation: AAK28743.1.
    AF310267 Genomic DNA. Translation: AAK28744.1.
    AF310268 Genomic DNA. Translation: AAK28745.1.
    AF310269 Genomic DNA. Translation: AAK28746.1.
    AF310270 Genomic DNA. Translation: AAK28747.1.
    AF310271 Genomic DNA. Translation: AAK28748.1.
    AF310272 Genomic DNA. Translation: AAK28749.1.
    AF310273 Genomic DNA. Translation: AAK28750.1.
    AF310274 Genomic DNA. Translation: AAK28751.1.
    AF310275 Genomic DNA. Translation: AAK28752.1.
    AF310276 Genomic DNA. Translation: AAK28753.1.
    AF310277 Genomic DNA. Translation: AAK28754.1.
    AF310278 Genomic DNA. Translation: AAK28755.1.
    AF310279 Genomic DNA. Translation: AAK28756.1.
    AF310280 Genomic DNA. Translation: AAK28757.1.
    AF310281 Genomic DNA. Translation: AAK28758.1.
    AF310282 Genomic DNA. Translation: AAK28759.1.
    AF310283 Genomic DNA. Translation: AAK28760.1.
    AF310284 Genomic DNA. Translation: AAK28761.1.
    AF310285 Genomic DNA. Translation: AAK28762.1.
    AF310286 Genomic DNA. Translation: AAK28763.1.
    AF310287 Genomic DNA. Translation: AAK28764.1.
    AF310288 Genomic DNA. Translation: AAK28765.1.
    AF310289 Genomic DNA. Translation: AAK28766.1.
    AF310290 Genomic DNA. Translation: AAK28767.1.
    AF310291 Genomic DNA. Translation: AAK28768.1.
    AF310292 Genomic DNA. Translation: AAK28769.1.
    AF310293 Genomic DNA. Translation: AAK28770.1.
    AF310294 Genomic DNA. Translation: AAK28771.1.
    AF310295 Genomic DNA. Translation: AAK28772.1.
    AF310296 Genomic DNA. Translation: AAK28773.1.
    AF310297 Genomic DNA. Translation: AAK28774.1.
    AF310298 Genomic DNA. Translation: AAK28775.1.
    AF310299 Genomic DNA. Translation: AAK28776.1.
    AF310300 Genomic DNA. Translation: AAK28777.1.
    AF310301 Genomic DNA. Translation: AAK28778.1.
    AF310302 Genomic DNA. Translation: AAK28779.1.
    AF310303 Genomic DNA. Translation: AAK28780.1.
    AF310304 Genomic DNA. Translation: AAK28781.1.
    AF310305 Genomic DNA. Translation: AAK28782.1.
    AF310306 Genomic DNA. Translation: AAK28783.1.
    AF310307 Genomic DNA. Translation: AAK28784.1.
    AF310308 Genomic DNA. Translation: AAK28785.1.
    AF310309 Genomic DNA. Translation: AAK28786.1.
    AF310310 Genomic DNA. Translation: AAK28787.1.
    AF310311 Genomic DNA. Translation: AAK28788.1.
    AF310312 Genomic DNA. Translation: AAK28789.1.
    AF310313 Genomic DNA. Translation: AAK28790.1.
    AF310314 Genomic DNA. Translation: AAK28791.1.
    AF310315 Genomic DNA. Translation: AAK28792.1.
    AF310316 Genomic DNA. Translation: AAK28793.1.
    AF310317 Genomic DNA. Translation: AAK28794.1.
    AF310318 Genomic DNA. Translation: AAK28795.1.
    AF310319 Genomic DNA. Translation: AAK28796.1.
    AF310320 Genomic DNA. Translation: AAK28797.1.
    AF310321 Genomic DNA. Translation: AAK28798.1.
    AF310322 Genomic DNA. Translation: AAK28799.1.
    AF310323 Genomic DNA. Translation: AAK28800.1.
    AF310324 Genomic DNA. Translation: AAK28801.1.
    AF310325 Genomic DNA. Translation: AAK28802.1.
    CCDSiCCDS1303.1. [Q9UBS9-1]
    CCDS65726.1. [Q9UBS9-2]
    PIRiJC7185.
    RefSeqiNP_001269679.1. NM_001282750.1.
    NP_001269680.1. NM_001282751.1.
    NP_055098.1. NM_014283.4. [Q9UBS9-1]
    NP_057311.3. NM_016227.3. [Q9UBS9-2]
    UniGeneiHs.204559.

    Genome annotation databases

    EnsembliENST00000263688; ENSP00000263688; ENSG00000094975. [Q9UBS9-1]
    ENST00000367723; ENSP00000356696; ENSG00000094975. [Q9UBS9-2]
    GeneIDi51430.
    KEGGihsa:51430.
    UCSCiuc001giq.4. human. [Q9UBS9-1]
    uc009wwd.3. human. [Q9UBS9-2]

    Polymorphism databases

    DMDMi74761893.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ250075 mRNA. Translation: CAB57360.1 .
    AF097535 mRNA. Translation: AAF04619.1 .
    AL035291 mRNA. Translation: CAA22894.1 .
    Z96050 , Z94054 Genomic DNA. Translation: CAI19034.1 .
    Z94054 , Z96050 Genomic DNA. Translation: CAI19460.1 .
    BC137125 mRNA. Translation: AAI37126.1 .
    CH471067 Genomic DNA. Translation: EAW90931.1 .
    AF310265 Genomic DNA. Translation: AAK28742.1 .
    AF310266 Genomic DNA. Translation: AAK28743.1 .
    AF310267 Genomic DNA. Translation: AAK28744.1 .
    AF310268 Genomic DNA. Translation: AAK28745.1 .
    AF310269 Genomic DNA. Translation: AAK28746.1 .
    AF310270 Genomic DNA. Translation: AAK28747.1 .
    AF310271 Genomic DNA. Translation: AAK28748.1 .
    AF310272 Genomic DNA. Translation: AAK28749.1 .
    AF310273 Genomic DNA. Translation: AAK28750.1 .
    AF310274 Genomic DNA. Translation: AAK28751.1 .
    AF310275 Genomic DNA. Translation: AAK28752.1 .
    AF310276 Genomic DNA. Translation: AAK28753.1 .
    AF310277 Genomic DNA. Translation: AAK28754.1 .
    AF310278 Genomic DNA. Translation: AAK28755.1 .
    AF310279 Genomic DNA. Translation: AAK28756.1 .
    AF310280 Genomic DNA. Translation: AAK28757.1 .
    AF310281 Genomic DNA. Translation: AAK28758.1 .
    AF310282 Genomic DNA. Translation: AAK28759.1 .
    AF310283 Genomic DNA. Translation: AAK28760.1 .
    AF310284 Genomic DNA. Translation: AAK28761.1 .
    AF310285 Genomic DNA. Translation: AAK28762.1 .
    AF310286 Genomic DNA. Translation: AAK28763.1 .
    AF310287 Genomic DNA. Translation: AAK28764.1 .
    AF310288 Genomic DNA. Translation: AAK28765.1 .
    AF310289 Genomic DNA. Translation: AAK28766.1 .
    AF310290 Genomic DNA. Translation: AAK28767.1 .
    AF310291 Genomic DNA. Translation: AAK28768.1 .
    AF310292 Genomic DNA. Translation: AAK28769.1 .
    AF310293 Genomic DNA. Translation: AAK28770.1 .
    AF310294 Genomic DNA. Translation: AAK28771.1 .
    AF310295 Genomic DNA. Translation: AAK28772.1 .
    AF310296 Genomic DNA. Translation: AAK28773.1 .
    AF310297 Genomic DNA. Translation: AAK28774.1 .
    AF310298 Genomic DNA. Translation: AAK28775.1 .
    AF310299 Genomic DNA. Translation: AAK28776.1 .
    AF310300 Genomic DNA. Translation: AAK28777.1 .
    AF310301 Genomic DNA. Translation: AAK28778.1 .
    AF310302 Genomic DNA. Translation: AAK28779.1 .
    AF310303 Genomic DNA. Translation: AAK28780.1 .
    AF310304 Genomic DNA. Translation: AAK28781.1 .
    AF310305 Genomic DNA. Translation: AAK28782.1 .
    AF310306 Genomic DNA. Translation: AAK28783.1 .
    AF310307 Genomic DNA. Translation: AAK28784.1 .
    AF310308 Genomic DNA. Translation: AAK28785.1 .
    AF310309 Genomic DNA. Translation: AAK28786.1 .
    AF310310 Genomic DNA. Translation: AAK28787.1 .
    AF310311 Genomic DNA. Translation: AAK28788.1 .
    AF310312 Genomic DNA. Translation: AAK28789.1 .
    AF310313 Genomic DNA. Translation: AAK28790.1 .
    AF310314 Genomic DNA. Translation: AAK28791.1 .
    AF310315 Genomic DNA. Translation: AAK28792.1 .
    AF310316 Genomic DNA. Translation: AAK28793.1 .
    AF310317 Genomic DNA. Translation: AAK28794.1 .
    AF310318 Genomic DNA. Translation: AAK28795.1 .
    AF310319 Genomic DNA. Translation: AAK28796.1 .
    AF310320 Genomic DNA. Translation: AAK28797.1 .
    AF310321 Genomic DNA. Translation: AAK28798.1 .
    AF310322 Genomic DNA. Translation: AAK28799.1 .
    AF310323 Genomic DNA. Translation: AAK28800.1 .
    AF310324 Genomic DNA. Translation: AAK28801.1 .
    AF310325 Genomic DNA. Translation: AAK28802.1 .
    CCDSi CCDS1303.1. [Q9UBS9-1 ]
    CCDS65726.1. [Q9UBS9-2 ]
    PIRi JC7185.
    RefSeqi NP_001269679.1. NM_001282750.1.
    NP_001269680.1. NM_001282751.1.
    NP_055098.1. NM_014283.4. [Q9UBS9-1 ]
    NP_057311.3. NM_016227.3. [Q9UBS9-2 ]
    UniGenei Hs.204559.

    3D structure databases

    ProteinModelPortali Q9UBS9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119536. 2 interactions.
    STRINGi 9606.ENSP00000263688.

    Polymorphism databases

    DMDMi 74761893.

    Proteomic databases

    MaxQBi Q9UBS9.
    PaxDbi Q9UBS9.
    PRIDEi Q9UBS9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000263688 ; ENSP00000263688 ; ENSG00000094975 . [Q9UBS9-1 ]
    ENST00000367723 ; ENSP00000356696 ; ENSG00000094975 . [Q9UBS9-2 ]
    GeneIDi 51430.
    KEGGi hsa:51430.
    UCSCi uc001giq.4. human. [Q9UBS9-1 ]
    uc009wwd.3. human. [Q9UBS9-2 ]

    Organism-specific databases

    CTDi 51430.
    GeneCardsi GC01P172502.
    HGNCi HGNC:1240. SUCO.
    HPAi HPA047251.
    neXtProti NX_Q9UBS9.
    PharmGKBi PA25621.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG314762.
    HOGENOMi HOG000070169.
    HOVERGENi HBG107549.
    PhylomeDBi Q9UBS9.
    TreeFami TF105817.

    Miscellaneous databases

    ChiTaRSi C1orf9. human.
    GenomeRNAii 51430.
    NextBioi 54995.
    PROi Q9UBS9.

    Gene expression databases

    ArrayExpressi Q9UBS9.
    Bgeei Q9UBS9.
    CleanExi HS_C1orf9.
    Genevestigatori Q9UBS9.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    InterProi IPR008979. Galactose-bd-like.
    IPR012919. Sad1_UNC_C.
    [Graphical view ]
    Pfami PF07738. Sad1_UNC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49785. SSF49785. 1 hit.
    PROSITEi PS51469. SUN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The C1orf9 gene encodes a putative transmembrane member of a novel protein family."
      Roesok O., Pedeutour F., Odeberg J., Lundeberg J., Aasheim H.-C.
      Biochem. Biophys. Res. Commun. 267:855-862(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
      Tissue: Testis.
    2. "Cloning of an overexpressed gene on chromosome 1 in breast cancer defines a new gene family."
      Chen L.-C., Cheung J., Moore D., Ljung B.-M., Kuo W.-L., Collins C., Gray J.W., Smith H.S.
      Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
      Tissue: Mammary gland.
    3. Rhodes S.
      Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    4. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    7. "Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1."
      Yu N., Zhao Z., Fu Y.-X., Sambuughin N., Ramsay M., Jenkins T., Leskinen E., Patthy L., Jorde L.B., Kuromori T., Li W.-H.
      Mol. Biol. Evol. 18:214-222(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 22-244.
    8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.

    Entry informationi

    Entry nameiSUCO_HUMAN
    AccessioniPrimary (citable) accession number: Q9UBS9
    Secondary accession number(s): B2RNU4
    , Q9BQB9, Q9BXQ2, Q9UL04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3