Q9UBL0 (ARP21_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
cAMP-regulated phosphoprotein 21
Short name=ARPP-21

Alternative name(s):
Thymocyte cAMP-regulated phosphoprotein

Gene names

Name:	ARPP21
Synonyms:	TARPP

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	812 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons By similarity.
Subunit structure	Interacts with CALM1 By similarity.
Subcellular location	Cytoplasm By similarity.
Tissue specificity	Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). Ref.1 Ref.8
Post-translational modification	Phosphorylation at Ser-56 favors interaction with CALM1 By similarity. Isoform 1 is methylated by CARM1 in immature thymocytes Probable. Ref.8
Sequence similarities	Contains 1 R3H domain. Contains 1 SUZ domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Coding sequence diversity	Alternative splicing
Domain	Coiled coil
Ligand	Calmodulin-binding
PTM	Acetylation Methylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular response to heat Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9UBL0-1)

Also known as: TARPP;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9UBL0-2)

Also known as: ARPP-21;

The sequence of this isoform differs from the canonical sequence as follows:
     88-89: ES → TL
     90-812: Missing.

Isoform 3 (identifier: Q9UBL0-3)

The sequence of this isoform differs from the canonical sequence as follows:
     266-299: Missing.
     548-548: Q → QSVQGLQASSQSVQYPAVSFPPQHLLPVSPTQHFPM

Isoform 4 (identifier: Q9UBL0-4)

The sequence of this isoform differs from the canonical sequence as follows:
     266-299: Missing.
     312-331: Missing.
     548-548: Q → QSVQGLQASSQSVQYPAVSFPPQHLLPVSPTQHFPM

Isoform 5 (identifier: Q9UBL0-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-512: Missing.
     548-548: Q → QSVQGLQASSQSVQYPAVSFPPQHLLPVSPTQHFPM

Note: No experimental confirmation available.

Isoform 6 (identifier: Q9UBL0-6)

The sequence of this isoform differs from the canonical sequence as follows:
     88-108: ESIHLQLSSFSSLQEEDKSRK → VYPLAIIINCMNGIHLCVHDS
     109-812: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 812	811	cAMP-regulated phosphoprotein 21		PRO_0000064682
Regions
	Domain	164 – 227	64	R3H
	Domain	245 – 299	55	SUZ
	Coiled coil	32 – 58	27	Potential
	Compositional bias	338 – 423	86	Ser-rich
	Compositional bias	506 – 754	249	Gln-rich
Amino acid modifications
	Modified residue	2	1	N-acetylserine By similarity
	Modified residue	33	1	Phosphoserine Ref.9
	Modified residue	56	1	Phosphoserine By similarity
	Modified residue	280	1	Phosphoserine By similarity
	Modified residue	383	1	Phosphoserine Ref.9
	Modified residue	562	1	Phosphoserine Ref.9
	Modified residue	655	1	Omega-N-methylated arginine Probable
Natural variations
	Alternative sequence	1 – 512	512	Missing in isoform 5.		VSP_029469
	Alternative sequence	88 – 108	21	ESIHL…DKSRK → VYPLAIIINCMNGIHLCVHD S in isoform 6.		VSP_029470
	Alternative sequence	88 – 89	2	ES → TL in isoform 2.		VSP_029471
	Alternative sequence	90 – 812	723	Missing in isoform 2.		VSP_029472
	Alternative sequence	109 – 812	704	Missing in isoform 6.		VSP_029473
	Alternative sequence	266 – 299	34	Missing in isoform 3 and isoform 4.		VSP_029474
	Alternative sequence	312 – 331	20	Missing in isoform 4.		VSP_029475
	Alternative sequence	548	1	Q → QSVQGLQASSQSVQYPAVSF PPQHLLPVSPTQHFPM in isoform 3, isoform 4 and isoform 5.		VSP_029476
Experimental info
	Sequence conflict	312	1	Missing in CAB61414. Ref.6

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (TARPP) [UniParc]. Last modified November 13, 2007. Version 2. Checksum: 73981A8341BB3359	FASTA	812	89,196
	10 20 30 40 50 60 MSEQGDLNQA IAEEGGTEQE TATPENGIVK SESLDEEEKL ELQRRLEAQN QERRKSKSGA 70 80 90 100 110 120 GKGKLTRSLA VCEESSARPG GESLQDQESI HLQLSSFSSL QEEDKSRKDD SEREKEKDKN 130 140 150 160 170 180 KDKTSEKPKI RMLSKDCSQE YTDSTGIDLH EFLINTLKNN SRDRMILLKM EQEIIDFIAD 190 200 210 220 230 240 NNNHYKKFPQ MSSYQRMLVH RVAAYFGLDH NVDQTGKSVI INKTSSTRIP EQRFCEHLKD 250 260 270 280 290 300 EKGEESQKRF ILKRDNSSID KEDNQQNRMH PFRDDRRSKS IEEREEEYQR VRERIFAHDS 310 320 330 340 350 360 VCSQESLFVE NSRLLEDSNI CNETYKKRQL FRGNRDGSGR TSGSRQSSSE NELKWSDHQR 370 380 390 400 410 420 AWSSTDSDSS NRNLKPAMTK TASFGGITVL TRGDSTSSTR STGKLSKAGS ESSSSAGSSG 430 440 450 460 470 480 SLSRTHPPLQ STPLVSGVAA GSPGCVPYPE NGIGGQVAPS STSYILLPLE AATGIPPGSI 490 500 510 520 530 540 LLNPHTGQPF VNPDGTPAIY NPPTSQQPLR SAMVGQSQQQ PPQQQPSPQP QQQVQPPQPQ 550 560 570 580 590 600 MAGPLVTQRD DVATQFGQMT LSRQSSGETP EPPSGPVYPS SLMPQPAQQP SYVIASTGQQ 610 620 630 640 650 660 LPTGGFSGSG PPISQQVLQP PPSPQGFVQQ PPPAQMPVYY YPSGQYPTST TQQYRPMAPV 670 680 690 700 710 720 QYNAQRSQQM PQAAQQAGYQ PVLSGQQGFQ GLIGVQQPPQ SQNVINNQQG TPVQSVMVSY 730 740 750 760 770 780 PTMSSYQVPM TQGSQGLPQQ SYQQPIMLPN QAGQGSLPAT GMPVYCNVTP PTPQNNLRLI 790 800 810 GPHCPSSTVP VMSASCRTNC ASMSNAGWQV KF
	Isoform 2 (ARPP-21) [UniParc]. Checksum: 94654817C61B4C94	FASTA	89	9,674
	10 20 30 40 50 60 MSEQGDLNQA IAEEGGTEQE TATPENGIVK SESLDEEEKL ELQRRLEAQN QERRKSKSGA 70 80 GKGKLTRSLA VCEESSARPG GESLQDQTL
	Isoform 3 [UniParc]. Checksum: 1F6E07737C11CC45	FASTA	813	88,570
	10 20 30 40 50 60 MSEQGDLNQA IAEEGGTEQE TATPENGIVK SESLDEEEKL ELQRRLEAQN QERRKSKSGA 70 80 90 100 110 120 GKGKLTRSLA VCEESSARPG GESLQDQESI HLQLSSFSSL QEEDKSRKDD SEREKEKDKN 130 140 150 160 170 180 KDKTSEKPKI RMLSKDCSQE YTDSTGIDLH EFLINTLKNN SRDRMILLKM EQEIIDFIAD 190 200 210 220 230 240 NNNHYKKFPQ MSSYQRMLVH RVAAYFGLDH NVDQTGKSVI INKTSSTRIP EQRFCEHLKD 250 260 270 280 290 300 EKGEESQKRF ILKRDNSSID KEDNQSVCSQ ESLFVENSRL LEDSNICNET YKKRQLFRGN 310 320 330 340 350 360 RDGSGRTSGS RQSSSENELK WSDHQRAWSS TDSDSSNRNL KPAMTKTASF GGITVLTRGD 370 380 390 400 410 420 STSSTRSTGK LSKAGSESSS SAGSSGSLSR THPPLQSTPL VSGVAAGSPG CVPYPENGIG 430 440 450 460 470 480 GQVAPSSTSY ILLPLEAATG IPPGSILLNP HTGQPFVNPD GTPAIYNPPT SQQPLRSAMV 490 500 510 520 530 540 GQSQQQPPQQ QPSPQPQQQV QPPQPQMAGP LVTQSVQGLQ ASSQSVQYPA VSFPPQHLLP 550 560 570 580 590 600 VSPTQHFPMR DDVATQFGQM TLSRQSSGET PEPPSGPVYP SSLMPQPAQQ PSYVIASTGQ 610 620 630 640 650 660 QLPTGGFSGS GPPISQQVLQ PPPSPQGFVQ QPPPAQMPVY YYPSGQYPTS TTQQYRPMAP 670 680 690 700 710 720 VQYNAQRSQQ MPQAAQQAGY QPVLSGQQGF QGLIGVQQPP QSQNVINNQQ GTPVQSVMVS 730 740 750 760 770 780 YPTMSSYQVP MTQGSQGLPQ QSYQQPIMLP NQAGQGSLPA TGMPVYCNVT PPTPQNNLRL 790 800 810 IGPHCPSSTV PVMSASCRTN CASMSNAGWQ VKF
	Isoform 4 [UniParc]. Checksum: F523AEF3E39114BE	FASTA	793	86,131
	10 20 30 40 50 60 MSEQGDLNQA IAEEGGTEQE TATPENGIVK SESLDEEEKL ELQRRLEAQN QERRKSKSGA 70 80 90 100 110 120 GKGKLTRSLA VCEESSARPG GESLQDQESI HLQLSSFSSL QEEDKSRKDD SEREKEKDKN 130 140 150 160 170 180 KDKTSEKPKI RMLSKDCSQE YTDSTGIDLH EFLINTLKNN SRDRMILLKM EQEIIDFIAD 190 200 210 220 230 240 NNNHYKKFPQ MSSYQRMLVH RVAAYFGLDH NVDQTGKSVI INKTSSTRIP EQRFCEHLKD 250 260 270 280 290 300 EKGEESQKRF ILKRDNSSID KEDNQSVCSQ ESLFVENRGN RDGSGRTSGS RQSSSENELK 310 320 330 340 350 360 WSDHQRAWSS TDSDSSNRNL KPAMTKTASF GGITVLTRGD STSSTRSTGK LSKAGSESSS 370 380 390 400 410 420 SAGSSGSLSR THPPLQSTPL VSGVAAGSPG CVPYPENGIG GQVAPSSTSY ILLPLEAATG 430 440 450 460 470 480 IPPGSILLNP HTGQPFVNPD GTPAIYNPPT SQQPLRSAMV GQSQQQPPQQ QPSPQPQQQV 490 500 510 520 530 540 QPPQPQMAGP LVTQSVQGLQ ASSQSVQYPA VSFPPQHLLP VSPTQHFPMR DDVATQFGQM 550 560 570 580 590 600 TLSRQSSGET PEPPSGPVYP SSLMPQPAQQ PSYVIASTGQ QLPTGGFSGS GPPISQQVLQ 610 620 630 640 650 660 PPPSPQGFVQ QPPPAQMPVY YYPSGQYPTS TTQQYRPMAP VQYNAQRSQQ MPQAAQQAGY 670 680 690 700 710 720 QPVLSGQQGF QGLIGVQQPP QSQNVINNQQ GTPVQSVMVS YPTMSSYQVP MTQGSQGLPQ 730 740 750 760 770 780 QSYQQPIMLP NQAGQGSLPA TGMPVYCNVT PPTPQNNLRL IGPHCPSSTV PVMSASCRTN 790 CASMSNAGWQ VKF
	Isoform 5 [UniParc]. Checksum: 3AF26F827EDD5066	FASTA	335	35,931
	10 20 30 40 50 60 MVGQSQQQPP QQQPSPQPQQ QVQPPQPQMA GPLVTQSVQG LQASSQSVQY PAVSFPPQHL 70 80 90 100 110 120 LPVSPTQHFP MRDDVATQFG QMTLSRQSSG ETPEPPSGPV YPSSLMPQPA QQPSYVIAST 130 140 150 160 170 180 GQQLPTGGFS GSGPPISQQV LQPPPSPQGF VQQPPPAQMP VYYYPSGQYP TSTTQQYRPM 190 200 210 220 230 240 APVQYNAQRS QQMPQAAQQA GYQPVLSGQQ GFQGLIGVQQ PPQSQNVINN QQGTPVQSVM 250 260 270 280 290 300 VSYPTMSSYQ VPMTQGSQGL PQQSYQQPIM LPNQAGQGSL PATGMPVYCN VTPPTPQNNL 310 320 330 RLIGPHCPSS TVPVMSASCR TNCASMSNAG WQVKF
	Isoform 6 [UniParc]. Checksum: 2AABF43866F7CCE8	FASTA	108	11,768
	10 20 30 40 50 60 MSEQGDLNQA IAEEGGTEQE TATPENGIVK SESLDEEEKL ELQRRLEAQN QERRKSKSGA 70 80 90 100 GKGKLTRSLA VCEESSARPG GESLQDQVYP LAIIINCMNG IHLCVHDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue." Brene S., Lindefors N., Ehrlich M., Taubes T., Horiuchi A., Kopp J., Hall H., Sedvall G., Greengard P., Persson H. J. Neurosci. 14:985-998(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY. Tissue: Brain.
[2]	"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Hu R.-M., Han Z.-G., Song H.-D., Peng Y.-D., Huang Q.-H., Ren S.-X., Gu Y.-J., Huang C.-H., Li Y.-B., Jiang C.-L., Fu G., Zhang Q.-H., Gu B.-W., Dai M., Mao Y.-F., Gao G.-F., Rong R., Ye M. , Zhou J., Xu S.-H., Gu J., Shi J.-X., Jin W.-R., Zhang C.-K., Wu T.-M., Huang G.-Y., Chen Z., Chen M.-D., Chen J.-L. Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Hypothalamus.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Amygdala.
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 4; 5 AND 6). Tissue: Hippocampus, Lung and Testis.
[6]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 162-812 (ISOFORM 3). Tissue: Kidney.
[7]	"Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry." Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M., Peters E.C. Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Leukemic T-cell.
[8]	"Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development." Kim J., Lee J., Yadav N., Wu Q., Carter C., Richard S., Richie E., Bedford M.T. J. Biol. Chem. 279:25339-25344(2004) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY, METHYLATION AT ARG-655.
[9]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33; SER-383 AND SER-562, MASS SPECTROMETRY. Tissue: Leukemic T-cell.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF112220 mRNA. Translation: AAF17207.1. AK294484 mRNA. Translation: BAG57707.1. CH471055 Genomic DNA. Translation: EAW64471.1. BC017805 mRNA. Translation: AAH17805.1. BC031106 mRNA. Translation: AAH31106.1. BC036399 mRNA. Translation: AAH36399.1. BC041385 mRNA. Translation: AAH41385.1. BC051828 mRNA. Translation: AAH51828.1. BC066651 mRNA. Translation: AAH66651.1. AL133109 mRNA. Translation: CAB61414.1.
IPI	IPI00384250. IPI00418646. IPI00654599. IPI00790973. IPI00796479. IPI00873467.
PIR	T42644.
RefSeq	NP_001020239.1. NM_001025068.1. NP_001020240.1. NM_001025069.1. NP_001254545.1. NM_001267616.1. NP_001254546.1. NM_001267617.1. NP_001254547.1. NM_001267618.1. NP_001254548.1. NM_001267619.1. NP_057384.2. NM_016300.4. NP_938409.1. NM_198399.1.
UniGene	Hs.475902.
3D structure databases
ProteinModelPortal	Q9UBL0.
ModBase	Search...
Polymorphism databases
DMDM	160332340.
Proteomic databases
PaxDb	Q9UBL0.
PeptideAtlas	Q86V31.
PRIDE	Q9UBL0.
Protocols and materials databases
DNASU	10777.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000187397; ENSP00000187397; ENSG00000172995. ENST00000337271; ENSP00000337792; ENSG00000172995. ENST00000396481; ENSP00000379741; ENSG00000172995. ENST00000396482; ENSP00000379742; ENSG00000172995. ENST00000412048; ENSP00000390151; ENSG00000172995. ENST00000417925; ENSP00000412326; ENSG00000172995. ENST00000427542; ENSP00000401602; ENSG00000172995. ENST00000428373; ENSP00000412411; ENSG00000172995. ENST00000432682; ENSP00000389754; ENSG00000172995. ENST00000436702; ENSP00000397720; ENSG00000172995. ENST00000438071; ENSP00000410171; ENSG00000172995. ENST00000441454; ENSP00000406964; ENSG00000172995. ENST00000444190; ENSP00000405276; ENSG00000172995. ENST00000458225; ENSP00000414351; ENSG00000172995. ENST00000474696; ENSP00000417838; ENSG00000172995.
GeneID	10777.
KEGG	hsa:10777.
UCSC	uc003cga.3. human. uc003cgb.3. human. uc003cgf.3. human. uc003cgg.3. human.
Organism-specific databases
CTD	10777.
GeneCards	GC03P035680.
HGNC	HGNC:16968. ARPP21.
HPA	HPA017303.
MIM	605488. gene.
neXtProt	NX_Q9UBL0.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG295106.
HOVERGEN	HBG052192.
InParanoid	Q9UBL0.
OMA	CRTNCAS.
PhylomeDB	Q9UBL0.
Gene expression databases
ArrayExpress	Q9UBL0.
Bgee	Q9UBL0.
Genevestigator	Q9UBL0.
GermOnline	ENSG00000172995. Homo sapiens.
Family and domain databases
InterPro	IPR001374. R3H_ss-bd. IPR024771. SUZ. [Graphical view]
Pfam	PF01424. R3H. 1 hit. PF12752. SUZ. 1 hit. [Graphical view]
SMART	SM00393. R3H. 1 hit. [Graphical view]
PROSITE	PS51061. R3H. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	10777.
NextBio	40921.
PMAP-CutDB	Q9UBL0.
SOURCE	Search...

Entry information

Entry name

ARP21_HUMAN

Accession

Primary (citable) accession number: Q9UBL0
Secondary accession number(s): B4DG96 , Q49AK3, Q49AS6, Q4G0V4, Q6NYC3, Q86V31, Q9UF93

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	November 13, 2007
Last modified:	May 1, 2013
This is version 88 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.