##gff-version 3
Q9UBE8	UniProtKB	Chain	1	527	.	.	.	ID=PRO_0000186336;Note=Serine/threonine-protein kinase NLK	
Q9UBE8	UniProtKB	Domain	138	427	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9UBE8	UniProtKB	Region	1	304	.	.	.	Note=Required for interaction with TAB2;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O54949	
Q9UBE8	UniProtKB	Region	1	125	.	.	.	Note=Sufficient for interaction with DAPK3;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21454679;Dbxref=PMID:21454679	
Q9UBE8	UniProtKB	Region	22	72	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UBE8	UniProtKB	Region	90	140	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UBE8	UniProtKB	Region	124	416	.	.	.	Note=Sufficient for interaction with DAPK3;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21454679;Dbxref=PMID:21454679	
Q9UBE8	UniProtKB	Region	428	527	.	.	.	Note=Required for homodimerization and kinase activation and localization to the nucleus;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O54949	
Q9UBE8	UniProtKB	Region	434	527	.	.	.	Note=Required for interaction with TAB2;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O54949	
Q9UBE8	UniProtKB	Motif	298	300	.	.	.	Note=TQE	
Q9UBE8	UniProtKB	Compositional bias	25	53	.	.	.	Note=Basic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UBE8	UniProtKB	Active site	264	264	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
Q9UBE8	UniProtKB	Binding site	144	152	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9UBE8	UniProtKB	Binding site	167	167	.	.	.	Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9UBE8	UniProtKB	Modified residue	298	298	.	.	.	Note=Phosphothreonine%3B by autocatalysis;Ontology_term=ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:19369195,ECO:0007744|PubMed:19690332,ECO:0007744|PubMed:23186163;Dbxref=PMID:19369195,PMID:19690332,PMID:23186163	
Q9UBE8	UniProtKB	Modified residue	522	522	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19369195;Dbxref=PMID:19369195	
Q9UBE8	UniProtKB	Natural variant	177	177	.	.	.	ID=VAR_019549;Note=V->A;Dbxref=dbSNP:rs11871287	
Q9UBE8	UniProtKB	Natural variant	343	343	.	.	.	ID=VAR_042273;Note=In a glioblastoma multiforme sample%3B somatic mutation. A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=PMID:17344846	
Q9UBE8	UniProtKB	Mutagenesis	167	167	.	.	.	Note=Abrogates kinase activity. K->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20061393;Dbxref=PMID:20061393	
Q9UBE8	UniProtKB	Sequence conflict	25	25	.	.	.	Note=A->T;Ontology_term=ECO:0000305;evidence=ECO:0000305