Unreviewed, UniProtKB/TrEMBL Q9UAC5 (Q9UAC5_DROME)

Names and origin

Protein names

Submitted name:
    TRAF1 EMBL AAD47894.1

Gene names

Name:	Traf4 FlyBase FBgn0026319
Synonyms:	Traf1 EMBL AAD47894.1 FlyBase FBgn0026319, traf1 EMBL AAG21891.1
ORF Names:	CG3048 FlyBase FBgn0026319

Organism

Drosophila melanogaster (Fruit fly) EMBL AAD47894.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	412 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 MATH domain. RuleBase RU004402V0

Ontologies

Gene Ontology (GO)
Biological process	Toll signaling pathway Non-traceable author statement. Source: FlyBase asymmetric protein localization involved in cell fate determination Inferred from mutant phenotype. Source: FlyBase dorsal closure Traceable author statement. Source: FlyBase eye development Inferred from mutant phenotype. Source: FlyBase imaginal disc fusion, thorax closure Inferred from genetic interaction. Source: FlyBase instar larval development Inferred from expression pattern. Source: FlyBase phagocytosis, engulfment Inferred from mutant phenotype. Source: FlyBase positive regulation of JNK cascade Inferred from genetic interaction. Source: FlyBase positive regulation of apoptosis Inferred from mutant phenotype. Source: FlyBase salivary gland cell autophagic cell death Inferred from expression pattern. Source: FlyBase
Cellular component	apical cortex Inferred from direct assay. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9UAC5-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 81A05147AA7D64CE	FASTA	412	46,159
	10 20 30 40 50 60 MIVTYLQISY FPYLQIYPGP DPKHIMGSLV FCIHHKQGCK WSDELRKLKG HLNACKHDAT 70 80 90 100 110 120 QCPNKCGAQI PRIMMTDHLQ YTCTMRRTRC EFCQSEFSGA GLEEHNGSCG QEPVYCEAKC 130 140 150 160 170 180 GQRILRGRMT LHKSKDCAKR LRRCAHCQRE FSADTLPLHA AQCPRAPLAC PQRCDAGPIP 190 200 210 220 230 240 RGELEAHLRD ECQSLAVSCS FKEAGCRFKG PRQMLEAHLE SNAAAHLSLM VALSSRQGQQ 250 260 270 280 290 300 IQMLKSAVSK LSINYTGTLL WKITDWSAKM AEARGKDGLE LVSPPFYTSQ YGYKLQASMF 310 320 330 340 350 360 LNGNGPGENT HVSVYIKVLP GEYDALLKWP FSHSITFTLF EQGAQSGQGG VAESFVPDPT 370 380 390 400 410 WENFQRPSNE PDQLGFGFPR FISHELLHSR PFIKGDTVFL RVKVDPSKIV AV

References

[1]	"Drosophila TRAF proteins are components of innate host defense pathways." Medzhitov R., Janeway C. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Medzhitov R Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Identification of a Drosophila TRAF homolog." Richter B.W.M., Duckett C.S. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF079837 mRNA. Translation: AAD47894.1. AF111422 mRNA. Translation: AAG21891.1.
UniGene	Dm.3100
3D structure databases
HSSP	HSSP built from PDB template 1L0A based on UniProtKB Q13114.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9UAC5. 3 interactions.
Proteomic databases
PRIDE	Q9UAC5.
Genome annotation databases
Ensembl	FBgn0026319. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0026319. Traf4.
Gene expression databases
ArrayExpress	Q9UAC5.
Family and domain databases
InterPro	IPR002083. MATH. IPR012227. TNF_recpt_TRAF. IPR013322. TRAF-type. IPR001293. Znf_TRAF. [Graphical view]
Gene3D	G3DSA:2.60.210.10. TRAF-type. 1 hit.
Pfam	PF00917. MATH. 1 hit. PF02176. zf-TRAF. 2 hits. [Graphical view]
PIRSF	PIRSF015614. TRAF. 1 hit.
SMART	SM00061. MATH. 1 hit. [Graphical view]
PROSITE	PS50144. MATH. 1 hit. PS50145. ZF_TRAF. 3 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	784548.

Entry information

Entry name

Q9UAC5_DROME

Accession

Primary (citable) accession number: Q9UAC5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)