Unreviewed, UniProtKB/TrEMBL Q9UAC4 (Q9UAC4_DROME)

Names and origin

Protein names

Submitted name:
    TRAF6 EMBL AAD47895.1

Gene names

Name:	Traf6 FlyBase FBgn0026318 EMBL AAD47895.1
Synonyms:	Traf2 FlyBase FBgn0026318
ORF Names:	CG10961 FlyBase FBgn0026318

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAD47895.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Domain	Zinc-finger RuleBase RU000353V2
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	Toll signaling pathway Traceable author statement. Source: FlyBase dorsal closure Traceable author statement. Source: FlyBase innate immune response Inferred from mutant phenotype. Source: FlyBase regulation of I-kappaB kinase/NF-kappaB cascade Inferred from mutant phenotype. Source: FlyBase
Cellular component	intracellular Traceable author statement. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: IntAct zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ECSIT	Q9U6M0	1	EBI-527076,EBI-113428

Sequences

	Sequence		Length	Mass (Da)
	Q9UAC4-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 6FDACD1C0522B177	FASTA	475	54,031
	10 20 30 40 50 60 MQRVQADQKP ARMHQHAHTH SHAHSLQHAE EKEHNSNEMT TNLSSTGRIA AGSSATPSAQ 70 80 90 100 110 120 REGGASGDPT PPKSLALNQN HHYAPGSDTS GEQEEELLDS RYECAICIDW LNEPVLTSCG 130 140 150 160 170 180 HRFCRSCLTA WMQKNNQCCP MDNKRLSAEH DIFPDNYTRR EIEQLKRDCP NSSLGCSVVA 190 200 210 220 230 240 SPIELHRHLP SCPYRRQQEP QEEKCPFAKI KCDFVGRPET NQLEEHLKAD MPHHMQLMLQ 250 260 270 280 290 300 AFQQTAIATW QPHKPSTSGA AVENGHGQQQ LPPPPPYANG VDEQIVQTMY QRIVVLEQRT 310 320 330 340 350 360 REQETRLENM QKQLRLARQQ APVDSRYSNG TIVWRIEQLG ALVARLRANA NNQVYSHECY 370 380 390 400 410 420 TSPHGYKFCA RLNIQPRKPH VLSLHVHLMQ SENDYHLDWP FKGRIKLCMV HPADATLSQH 430 440 450 460 470 DTIMTKPEIL AFHKPREAIS TRGFGFLEYA NISNIIQLGF CADDRLLIKI EINIV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Drosophila TRAF proteins are components of innate host defense pathways." Medzhitov R., Janeway C. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Medzhitov R Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF079838 mRNA. Translation: AAD47895.1.
3D structure databases
HSSP	HSSP built from PDB template 1LB4 based on UniProtKB Q9Y4K3.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9UAC4. 2 interactions.
Proteomic databases
PRIDE	Q9UAC4.
Genome annotation databases
Ensembl	FBgn0026318. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0026318. Traf6.
Phylogenomic databases
HOGENOM	Q9UAC4.
Gene expression databases
ArrayExpress	Q9UAC4.
Family and domain databases
InterPro	IPR002083. MATH. IPR013322. TRAF-type. IPR018957. Znf_C3HC4_RING-type. IPR001841. Znf_RING. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:2.60.210.10. TRAF-type. 1 hit.
Pfam	PF00097. zf-C3HC4. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. [Graphical view]
PROSITE	PS50144. MATH. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UAC4_DROME

Accession

Primary (citable) accession number: Q9UAC4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)