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Protein
Submitted name:

Replication factor C 38kD subunit, isoform A

Gene

RfC38

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DME-110312 Translesion synthesis by REV1
R-DME-110314 Recognition of DNA damage by PCNA-containing replication complex
R-DME-110320 Translesion Synthesis by POLH
R-DME-174411 Polymerase switching on the C-strand of the telomere
R-DME-176187 Activation of ATR in response to replication stress
R-DME-5651801 PCNA-Dependent Long Patch Base Excision Repair
R-DME-5655862 Translesion synthesis by POLK
R-DME-5656121 Translesion synthesis by POLI
R-DME-5656169 Termination of translesion DNA synthesis
R-DME-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER
R-DME-5696400 Dual Incision in GG-NER
R-DME-6782135 Dual incision in TC-NER
R-DME-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER
R-DME-69091 Polymerase switching

Names & Taxonomyi

Protein namesi
Submitted name:
Replication factor C 38kD subunit, isoform AImported
Submitted name:
Replication factor C 38kD subunit, isoform BImported
Gene namesi
Name:RfC38Imported
Synonyms:BcDNA:LD06837Imported, Dmel\CG6258Imported, DmRFC5Imported, l(2)k13807Imported, l(2)rfc38Imported, n(2)k13807Imported, Rfc38Imported
ORF Names:CG6258Imported, Dmel_CG6258Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0028700 RfC38

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ9U9Q1

Expressioni

Gene expression databases

BgeeiFBgn0028700
ExpressionAtlasiQ9U9Q1 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ9U9Q1, 2 interactors
STRINGi7227.FBpp0079812

Structurei

3D structure databases

SMRiQ9U9Q1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 190AAAInterPro annotationAdd BLAST157

Phylogenomic databases

eggNOGiKOG2035 Eukaryota
COG0470 LUCA
GeneTreeiENSGT00550000075006
KOiK10756
OMAiLSHCIPP
OrthoDBiEOG091G0BQF

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR008921 DNA_pol3_clamp-load_cplx_C
IPR027417 P-loop_NTPase
IPR013748 Rep_factorC_C
PfamiView protein in Pfam
PF08542 Rep_fac_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF48019 SSF48019, 1 hit
SSF52540 SSF52540, 2 hits

Sequencei

Sequence statusi: Complete.

Q9U9Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALWVDKYRP RELSKLDFHK DQAENLRNLC KQSDFPHLMF YGPSGAGKKT
60 70 80 90 100
RIMCLLREMY GSGVERLRSE TMTFTTPSNR KVEVMTVSSN YHLEVNPSDA
110 120 130 140 150
GMYDRTVVID LIKQVAQTHQ IEISGQREFK VIVISEGDEL TKDAQHALRR
160 170 180 190 200
TMEKYVATCR IIISVNSTSR IIPAIRSRCL GIRVAAPNET EIVSILQNTC
210 220 230 240 250
KREGLALPVE LAKRVVDKSE RNLRRALLML EAAKVAKAPF TANQEIPDLD
260 270 280 290 300
WQVFLRETAS QIISEQTPAK LEKIRERLYE LLTQGVPPNL IFRGLVEQLV
310 320 330 340 350
NNCDMSIKAK TLEFATEYEH RMQSGAKHIF HLEAFVAQFM NIYKKFLSEL

DMTDDF
Length:356
Mass (Da):40,815
Last modified:May 1, 2000 - v1
Checksum:iD8155B1691BDB9D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53076.2
AE014134 Genomic DNA Translation: AHN54347.1
RefSeqiNP_001285833.1, NM_001298904.1
NP_609494.1, NM_135650.3

Genome annotation databases

EnsemblMetazoaiFBtr0080225; FBpp0079812; FBgn0028700
FBtr0344786; FBpp0311114; FBgn0028700
GeneIDi34550
KEGGidme:Dmel_CG6258
UCSCiCG6258-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9U9Q1_DROME
AccessioniPrimary (citable) accession number: Q9U9Q1
Secondary accession number(s): Q9VKJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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