Q9U968 (A29AB_DROSI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Accessory gland protein Acp29AB

Gene names

Name:

Acp29AB

Organism

Drosophila simulans (Fruit fly)

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Function	Responsible for physiological and behavioral changes in mated female flies.
Subcellular location	Secreted Probable.
Sequence similarities	Contains 1 C-type lectin domain.

Ontologies

Keywords
Biological process	Behavior
Cellular component	Secreted
Domain	Signal
Ligand	Lectin
PTM	Disulfide bond Glycoprotein
Gene Ontology (GO)
Biological process	behavior Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sugar binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 234	213	Accessory gland protein Acp29AB		PRO_0000017557
Regions
	Domain	137 – 234	98	C-type lectin
Amino acid modifications
	Glycosylation	29	1	N-linked (GlcNAc...) Potential
	Glycosylation	61	1	N-linked (GlcNAc...) Potential
	Glycosylation	127	1	N-linked (GlcNAc...) Potential
	Glycosylation	164	1	N-linked (GlcNAc...) Potential
	Disulfide bond	139 ↔ 228		By similarity
	Disulfide bond	207 ↔ 220		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9U968 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: EE9C556E02EFED98	FASTA	234	26,915
	10 20 30 40 50 60 MYATNLLYLL ALWNLWLVSG GQQDIPNGNA TLPSPQKPQN TIDQIGANQN YWFTYNALRQ 70 80 90 100 110 120 NETLAIIDAM ESGIASSVLA FQAQMEIQLQ PLKIIMLHHA GNIKASNNIK MSRFEKVGSR 130 140 150 160 170 180 YFHIEKNLTL TWFEAYVTCR EMNGHLANIR DEKELDGILA LAPNNSYWVD ISKLVEYGGT 190 200 210 220 230 FVSTLTGREP IFVKWKPNQD KKKQHNCVYI YAKEMYYDEC FEKKSFVCQA NQWA

References

[1]	"Positive selection drives the evolution of the Acp29AB accessory gland protein in Drosophila." Aguade M. Genetics 152:543-551(1999) [PubMed: 10353898] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: S9.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ240552 Genomic DNA. Translation: CAB53227.1.
3D structure databases
ProteinModelPortal	Q9U968.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0027418. Dsim\Acp29AB.
Phylogenomic databases
GeneTree	EMGT00050000001044.
OrthoDB	EOG4G1JZD.
Family and domain databases
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR016187. C-type_lectin_fold. [Graphical view]
Gene3D	G3DSA:3.10.100.10. C-type_lectin-like. 1 hit.
Pfam	PF00059. Lectin_C. 1 hit. [Graphical view]
SMART	SM00034. CLECT. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit.
PROSITE	PS00615. C_TYPE_LECTIN_1. False negative. PS50041. C_TYPE_LECTIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A29AB_DROSI

Accession

Primary (citable) accession number: Q9U968

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 16, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project