Q9U8G2 (Q9U8G2_9TRYP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Proteasome activator protein PA26 EMBL AAD50581.1
Organism	Trypanosoma brucei EMBL AAD50581.1
Taxonomic identifier	5691 [NCBI]
Taxonomic lineage	Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma

Protein attributes

Sequence length	231 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

Ontologies

Keywords
Cellular component	Proteasome EMBL AAD50581.1
Technical term	3D-structure PDB 1Z7Q PDB 1FNT PDB 1YAR PDB 1YAU PDB 1YA7 PDB 3JSE PDB 3JTL PDB 3JRM
Gene Ontology (GO)
Cellular component	proteasome activator complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	231	1	EMBL AAD50581.1

Sequences

	Sequence		Length	Mass (Da)
	Q9U8G2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 25FBF3F53DC6BE96	FASTA	231	25,230
	10 20 30 40 50 60 MPPKRAALIQ NLRDSYTETS SFAVIEEWAA GTLQEIEGIA KAAAEAHGTI RNSTYGRAQA 70 80 90 100 110 120 EKSPEQLLGV LQRYQDLCHN VYCQAETIRT VIAIRIPEHK EEDNLGVAVQ HAVLKIIDEL 130 140 150 160 170 180 EIKTLGSGEK SGSGGAPTPI GMYALREYLS ARSTVEDKLL GSVDAESGKT KGGSQSPSLL 190 200 210 220 230 LELRQIDADF MLKVELATTH LSTMVRAVIN AYLLNWKKLI QPRTGSDHMV S

References

[1]	"Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei." Yao Y., Huang L., Krutchinsky A., Wong M.L., Standing K.G., Burlingame A.L., Wang C.C. J. Biol. Chem. 274:33921-33930(1999) [PubMed: 10567354] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: brucei EMBL AAD50581.1.
[2]	"Structural basis for the activation of 20S proteasomes by 11S regulators." Whitby F.G., Masters E.I., Kramer L., Knowlton J.R., Yao Y., Wang C.C., Hill C.P. Nature 408:115-120(2000) [PubMed: 11081519] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS).
[3]	"The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions." Forster A., Masters E.I., Whitby F.G., Robinson H., Hill C.P. Mol. Cell 18:589-599(2005) [PubMed: 15916965] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 2-231.
[4]	"Structural models for interactions between the 20S proteasome and its PAN/19S activators." Stadtmueller B.M., Ferrell K., Whitby F.G., Heroux A., Robinson H., Myszka D.G., Hill C.P. J. Biol. Chem. 285:13-17(2010) [PubMed: 19889631] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 4-229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF085602 mRNA. Translation: AAD50581.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1FNT	X-ray	3.20	c/d/e/f/g/h/i/j/k/l/m/n/o/p	1-231	[»]
1YA7	X-ray	2.30	O/P/Q/R/S/T/U	2-231	[»]
1YAR	X-ray	1.90	O/P/Q/R/S/T/U	2-231	[»]
1YAU	X-ray	2.40	O/P/Q/R/S/T/U	2-231	[»]
1Z7Q	X-ray	3.22	c/d/e/f/g/h/i/j/k/l/m/n/o/p	1-231	[»]
3JRM	X-ray	2.90	O/P/Q/R/S/T/U	4-229	[»]
3JSE	X-ray	2.90	O/P/Q/R/S/T/U	4-229	[»]
3JTL	X-ray	3.20	O/P/Q/R/S/T/U	4-224	[»]

ProteinModelPortal

Q9U8G2.

ModBase

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Protein-protein interaction databases

IntAct

Q9U8G2. 1 interaction.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR003186. Proteasome_activ_REG_bsu.
[Graphical view]

Gene3D

G3DSA:1.20.120.180. PA28_beta. 1 hit.

ProtoNet

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Entry information

Entry name

Q9U8G2_9TRYP

Accession

Primary (citable) accession number: Q9U8G2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	October 19, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)