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Protein
Submitted name:

Glutathione s-transferase 6B

Gene

GST-6B

Organism
Musca domestica (House fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121GlutathioneCombined sources
Binding sitei113 – 1131GlutathioneCombined sources

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

BRENDAi2.5.1.18. 3486.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione s-transferase 6BImported (EC:2.5.1.18Imported)
Gene namesi
Name:GST-6BImported
OrganismiMusca domestica (House fly)Imported
Taxonomic identifieri7370 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaMuscoideaMuscidaeMusca

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VWXX-ray1.80A/B/C/D1-222[»]
ProteinModelPortaliQ9U795.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni53 – 553Glutathione bindingCombined sources
Regioni67 – 682Glutathione bindingCombined sources

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9U795-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKLVLYGID PSPPVRACLL TLKALNLPFE YKVVNLFAKE HLSEEYLKKN
60 70 80 90 100
PQHTVPTLEE DGHLIWDSHP IMAYLVSKYG KDDSLYPKDL LKRAVVDQRM
110 120 130 140 150
YFEAGVLFQG GLRNITAPLF FRNQTQIPQH QIDSIVESYG FLESFLKNNK
160 170 180 190 200
YMAGDHLTIA DFSIVTSVTS LVAFAEIDQS KFPKLSAWLK SLQSLPFYEE
210 220
ANGAGAKQLV AMVKSKNLTI VP
Length:222
Mass (Da):25,025
Last modified:May 1, 2000 - v1
Checksum:iB1740ABEFD4151FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF147206 mRNA. Translation: AAD54938.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF147206 mRNA. Translation: AAD54938.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VWXX-ray1.80A/B/C/D1-222[»]
ProteinModelPortaliQ9U795.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi2.5.1.18. 3486.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Glutathione S-transferase associated with OP-insecticide resistance in the housefly Musca domestica."
    Wei S.H., Syvanen M.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cornell-HRImported.
  2. "Structural analysis of an epsilon-class glutathione transferase from housefly, Musca domestica."
    Nakamura C., Yajima S., Miyamoto T., Sue M.
    Biochem. Biophys. Res. Commun. 430:1206-1211(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE.

Entry informationi

Entry nameiQ9U795_MUSDO
AccessioniPrimary (citable) accession number: Q9U795
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 1, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.