Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Palmitoyltransferase

Gene

Patsas

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotation, Transferase

Enzyme and pathway databases

SignaLinkiQ9U722.

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:PatsasImported
ORF Names:CG6618Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0029137. Patsas.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei230 – 250HelicalUniRule annotationAdd BLAST21
Transmembranei262 – 278HelicalUniRule annotationAdd BLAST17
Transmembranei359 – 383HelicalUniRule annotationAdd BLAST25
Transmembranei390 – 409HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

  • Golgi apparatus Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9U722.
PRIDEiQ9U722.

Expressioni

Gene expression databases

BgeeiFBgn0029137.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0079944.

Structurei

3D structure databases

ProteinModelPortaliQ9U722.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 198ANK_REP_REGIONInterPro annotationAdd BLAST195
Repeati10 – 38ANKPROSITE-ProRule annotationAdd BLAST29
Repeati45 – 77ANKPROSITE-ProRule annotationAdd BLAST33
Repeati78 – 110ANKPROSITE-ProRule annotationAdd BLAST33
Repeati111 – 143ANKPROSITE-ProRule annotationAdd BLAST33
Repeati144 – 164ANKPROSITE-ProRule annotationAdd BLAST21

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509. Eukaryota.
COG0666. LUCA.
COG5273. LUCA.
OrthoDBiEOG091G0CPB.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF13606. Ank_3. 2 hits.
PF01529. zf-DHHC. 1 hit.
SMARTiView protein in SMART
SM00248. ANK. 6 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.

Sequencei

Sequence statusi: Complete.

Q9U722-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MECLSARDRH GYTPAHWIAL NGXVQLMRYL IERTAPIDLP CLGTQGPRPI
60 70 80 90 100
HWACRKGHAS VVQVLLQAGV AVNAADFKGL TPLHLACMYG RTATAAYLLG
110 120 130 140 150
MGALNNLTDI NGDTALHWAA YKGHADLMRL LMYSGVELQK TDNFGSTPLH
160 170 180 190 200
LACLSGNMTC VRLLCEKSQL DLEPRDKNGK TPIMLAQAHQ HQDVVRLLYG
210 220 230 240 250
EVKKKSRWIP SVSESWGWLF GGAGDSKGPL FLFLFSVLLW GYPMYMIRAI
260 270 280 290 300
PITWNILRRS HYCFIYWNAV MWISWAIANR RDPGYIPLSS DAYYRAIKQI
310 320 330 340 350
PYFDKLKKRN VMLTRLCHSC RCLRPLRAKH CRVCNRCVSY FDHHCPFIYN
360 370 380 390 400
CVGLRNRMWF FLFVLSVAVN CSFTIYFACY CVMIEGFTML YVLGLIEAVV
410 420 430 440
FCGLGWILTC TSVSASFPKI LIVLTSFALA DPARLHESHH KRDV
Length:444
Mass (Da):50,444
Last modified:May 1, 2000 - v1
Checksum:i7BCFE02E28B2520C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163011 Genomic DNA. Translation: AAF00133.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163011 Genomic DNA. Translation: AAF00133.1.

3D structure databases

ProteinModelPortaliQ9U722.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0079944.

Proteomic databases

PaxDbiQ9U722.
PRIDEiQ9U722.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0029137. Patsas.

Phylogenomic databases

eggNOGiKOG0509. Eukaryota.
COG0666. LUCA.
COG5273. LUCA.
OrthoDBiEOG091G0CPB.

Enzyme and pathway databases

SignaLinkiQ9U722.

Gene expression databases

BgeeiFBgn0029137.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF13606. Ank_3. 2 hits.
PF01529. zf-DHHC. 1 hit.
SMARTiView protein in SMART
SM00248. ANK. 6 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9U722_DROME
AccessioniPrimary (citable) accession number: Q9U722
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 12, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.