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Protein
Submitted name:

Allatostatin A receptor 1, isoform B

Gene

AstA-R1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • allatostatin receptor activity Source: FlyBase
  • G-protein coupled receptor activity Source: FlyBase
  • neuropeptide receptor activity Source: FlyBase

GO - Biological processi

  • G-protein coupled receptor signaling pathway Source: FlyBase
  • neuropeptide signaling pathway Source: FlyBase
  • phospholipase C-activating G-protein coupled receptor signaling pathway Source: GO_Central
  • sensory perception of pain Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Allatostatin A receptor 1, isoform BImported
Submitted name:
Allatostatin A receptor 1, isoform DImported
Submitted name:
Allatostatin receptorImported
Submitted name:
FI18263p1Imported
Submitted name:
Galanin receptorImported
Gene namesi
Name:AstA-R1Imported
Synonyms:AlstRImported, AlstR-RBImported
ORF Names:CG2872Imported, Dmel_CG2872Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0266429. AstA-R1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei76 – 100HelicalSequence analysisAdd BLAST25
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21
Transmembranei152 – 170HelicalSequence analysisAdd BLAST19
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Transmembranei291 – 313HelicalSequence analysisAdd BLAST23
Transmembranei325 – 350HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

  • integral component of membrane Source: FlyBase
  • integral component of plasma membrane Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500878578025 – 394Sequence analysisAdd BLAST370

Expressioni

Gene expression databases

BgeeiFBgn0028961.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0070550.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 347G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00860000133695.
KOiK04233.
OMAiQYHGRAG.
OrthoDBiEOG091G0ZDG.

Family and domain databases

InterProiIPR000405. Galanin_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00663. GALANINR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9U721-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGHQSLALL LATLISSWPK ASWGATGNGS IISVSNSSGN NYAFTSEHTD
60 70 80 90 100
HSDHNANDSM EYDAESVALE RIVSTIVPVF FGIIGFAGLL GNGLVILVVV
110 120 130 140 150
ANQQMRSTTN LLIINLAVSD ILFVIFCVPF TATDYVLPEW PFGNVWCKFV
160 170 180 190 200
QYMIVVTCHC SVYTLVLMSF DRFLAVVHPV TSMSLRTERN ATLAIMCAWI
210 220 230 240 250
TIVTTAIPVA LSHSVRIYQY HGNAGTACVF STEEEIWSLV GFQVSFFLSS
260 270 280 290 300
YVAPLTLICF LYMGMLARLW KSAPGCKPSA ESRKGKRRVT RMVVVVVLAF
310 320 330 340 350
AICWLPIHVI LVLKALNLYG GSHLSVIIQI ISHVVAYTNS CINPILYAFL
360 370 380 390
SDNFRKAFRK VVWCGSPPPL MTNQQVTKTT RTATGNGTSN IEML
Length:394
Mass (Da):43,269
Last modified:May 1, 2000 - v1
Checksum:i865B140226B13C1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163775 mRNA. Translation: AAF05299.1.
AF220216 mRNA. Translation: AAF33781.1.
AE014298 Genomic DNA. Translation: AAF45884.3.
AE014298 Genomic DNA. Translation: AAG22404.3.
BT150204 mRNA. Translation: AGT59572.1.
PIRiJC7209.
RefSeqiNP_524700.1. NM_079961.4.
NP_726877.2. NM_166982.2.
UniGeneiDm.1859.

Genome annotation databases

EnsemblMetazoaiFBtr0070575; FBpp0070550; FBgn0266429.
FBtr0333798; FBpp0305932; FBgn0266429.
GeneIDi44126.
KEGGidme:Dmel_CG2872.
UCSCiCG2872-RB. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163775 mRNA. Translation: AAF05299.1.
AF220216 mRNA. Translation: AAF33781.1.
AE014298 Genomic DNA. Translation: AAF45884.3.
AE014298 Genomic DNA. Translation: AAG22404.3.
BT150204 mRNA. Translation: AGT59572.1.
PIRiJC7209.
RefSeqiNP_524700.1. NM_079961.4.
NP_726877.2. NM_166982.2.
UniGeneiDm.1859.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0070550.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0070575; FBpp0070550; FBgn0266429.
FBtr0333798; FBpp0305932; FBgn0266429.
GeneIDi44126.
KEGGidme:Dmel_CG2872.
UCSCiCG2872-RB. d. melanogaster.

Organism-specific databases

CTDi44126.
FlyBaseiFBgn0266429. AstA-R1.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00860000133695.
KOiK04233.
OMAiQYHGRAG.
OrthoDBiEOG091G0ZDG.

Miscellaneous databases

GenomeRNAii44126.

Gene expression databases

BgeeiFBgn0028961.

Family and domain databases

InterProiIPR000405. Galanin_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00663. GALANINR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9U721_DROME
AccessioniPrimary (citable) accession number: Q9U721
Secondary accession number(s): Q9W4R0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.