Q9U6R7 (Q9U6R7_DERFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: 98kDa HDM allergen EMBL AAD52672.1 Submitted name: Group 15 allergen Der f 15 EMBL ABU97469.1
Organism	Dermatophagoides farinae (American house dust mite) EMBL AAD52672.1
Taxonomic identifier	6954 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Acari › Acariformes › Sarcoptiformes › Astigmata › Psoroptidia › Analgoidea › Pyroglyphidae › Dermatophagoidinae › Dermatophagoides

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 18 family. RuleBase RU004453

Ontologies

Keywords
Molecular function	Glycosidase RuleBase RU000489 Hydrolase
Gene Ontology (GO)
Biological process	chitin catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro chitin binding Inferred from electronic annotation. Source: InterPro chitinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9U6R7 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 0E4564A1A459B30B	FASTA	555	63,238
	10 20 30 40 50 60 MKTIYAILSI MACIGLMNAS IKRDHNDYSK NPMRIVCYVG TWSVYHKVDP YTIEDIDPFK 70 80 90 100 110 120 CTHLMYGFAK IDEYKYTIQV FDPYQDDNHN SWEKRGYERF NNLRLKNPEL TTMISLGGWY 130 140 150 160 170 180 EGSEKYSDMA ANPTYRQQFI QSVLDFLQEY KFDGLDLDWE YPGSRLGNPK IDKQNYLALV 190 200 210 220 230 240 RELKDAFEPH GYLLTAAVSP GKDKIDRAYD IKELNKLFDW MNVMTYDYHG GWENFYGHNA 250 260 270 280 290 300 PLYKRPDETD ELHTYFNVNY TMHYYLNNGA TRDKLVMGVP FYGRAWSIED RSKLKLGDPA 310 320 330 340 350 360 KGMSPPGFIS GEEGVLSYIE LCQLFQKEEW HIQYDEYYNA PYGYNDKIWV GYDDLASISC 370 380 390 400 410 420 KLAFLKELGV SGVMVWSLEN DDFKGHCGPK NPLLNKVHNM INGDEKNSFE CILGPSTTTP 430 440 450 460 470 480 TPTTTPTTPT TTPTTPSPTT PTTTPSPTTP TTTPSPTTPT TTPSPTTPTP TTPTPAPTTS 490 500 510 520 530 540 TPSPTTTEHT SETPKYTTYV DGHLIKCYKE GDIPHPTNIH KYLVCEFVNG GWWVHIMPCP 550 PGTIWCQEKL TCIGE

References

[1]	"Characterization and cloning of a major high molecular weight house dust mite allergen (Der f 15) for dogs." McCall C., Hunter S., Stedman K., Weber E., Hillier A., Bozic C., Rivoire B., Olivry T. Vet. Immunol. Immunopathol. 78:231-247(2001) [PubMed: 11292526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Identification and cloning of Der f 15 allergen from Dermatophagoides farinae expressed sequence tags." Chew F.T., Ong S.T., Lim S.H., Tsai L.-C., Lee B.W. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Weber E.R., Hunter S., Stedman K., McCall C. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF178772 mRNA. Translation: AAD52672.1. EU106618 mRNA. Translation: ABU97469.1.
3D structure databases
HSSP	HSSP built from PDB template 1LG2 based on UniProtKB Q13231.
ProteinModelPortal	Q9U6R7.
ModBase	Search...
Protein family/group databases
Allergome	3251. Der f 15.0101. 697. Der f 15.
CAZy	CBM14. Carbohydrate-Binding Module Family 14. GH18. Glycoside Hydrolase Family 18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002557. Chitin-bd_dom. IPR011583. Chitinase_II. IPR001223. Glyco_hydro18cat. IPR001579. Glyco_hydro_18_chit_AS. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:2.170.140.10. Chitin-bd_dom. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits.
Pfam	PF01607. CBM_14. 1 hit. PF00704. Glyco_hydro_18. 1 hit. [Graphical view]
SMART	SM00494. ChtBD2. 1 hit. SM00636. Glyco_18. 1 hit. [Graphical view]
SUPFAM	SSF57625. Chitin_bind_PerA. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS01095. CHITINASE_18. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9U6R7_DERFA

Accession

Primary (citable) accession number: Q9U6R7

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 16, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)