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Protein
Submitted name:

Minichromosome maintenance 5 protein

Gene

MCM5

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replicationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Minichromosome maintenance 5 proteinImported
Gene namesi
Name:MCM5Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ9U3X1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini209 – 415207MCMInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MCM family.UniRule annotationSAAS annotation
Contains MCM domain.SAAS annotation

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
3.40.50.300. 1 hit.
InterProiIPR031327. MCM.
IPR008048. MCM5.
IPR018525. MCM_CS.
IPR001208. MCM_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00493. MCM. 1 hit.
[Graphical view]
PRINTSiPR01657. MCMFAMILY.
PR01661. MCMPROTEIN5.
SMARTiSM00350. MCM. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9U3X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGWEKKEDY IESDTGGPMM QVIIKDTQSK MIQPRMLQSS FLSKVIRVSG
60 70 80 90 100
IIVSISRVEP KVTKAILRCK LQKEIAVIVP SCCGIINYPK SCDGVSPVTG
110 120 130 140 150
KKCPPDPYDV VTEKCKFVDR IVLKLQETPE NVAPGEVPRT VTVIFRNDIC
160 170 180 190 200
LLLDLTAGQR IFIEGIFGAC LQRKGTISTS YIRAIGIEIS GQVVSQDDRR
210 220 230 240 250
MKEVARTITK EKLIKSIAPA ICGYDDIKEA VLCLMLGGSG KALPDGTHLR
260 270 280 290 300
GDINVLLMGD PGTAKSQLLK FVQMATPIGV YTSGKGSSAA GLTAAVNKDS
310 320 330 340 350
STGEFYLNGG ALVLGDGGVV CIDEFDKMNE VDRVAIHEAM EQQTISIAKA
360 370 380 390 400
GITAVLNARS AVLAAANPSF GRFNERASFG DNVNLKTTIL SRFDMIFMIR
410 420 430 440 450
DKHDAKRDKE IVKHYYGYSI VKRKVDNLSQ AFKEYIAYCK AYCIPRLTVN
460 470 480 490 500
ASNKLSNYFV SIRQKVRENK LENDNDEGIP ITVRQLEAII RISEALAKMT
510 520
MSDIADENHV DEAIRLFELS TMNSAVR
Length:527
Mass (Da):58,012
Last modified:May 1, 2000 - v1
Checksum:i543D8BEE3EAFAEFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF211951 mRNA. Translation: AAF18476.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF211951 mRNA. Translation: AAF18476.1.

3D structure databases

ProteinModelPortaliQ9U3X1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
3.40.50.300. 1 hit.
InterProiIPR031327. MCM.
IPR008048. MCM5.
IPR018525. MCM_CS.
IPR001208. MCM_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00493. MCM. 1 hit.
[Graphical view]
PRINTSiPR01657. MCMFAMILY.
PR01661. MCMPROTEIN5.
SMARTiSM00350. MCM. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Constitutive association of Mcm2-3-5 proteins with chromatin in Entamoeba histolytica."
    Das S., Mukherjee C., Sinha P., Lohia A.
    Cell. Microbiol. 7:259-267(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM1:IMSSImported.

Entry informationi

Entry nameiQ9U3X1_ENTHI
AccessioniPrimary (citable) accession number: Q9U3X1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 11, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.