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Protein
Submitted name:

U2AF splicing factor

Gene

uaf-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri20 – 48C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri158 – 185C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • pre-mRNA 3'-splice site binding Source: WormBase

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-CEL-109688 Cleavage of Growing Transcript in the Termination Region
R-CEL-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-CEL-72163 mRNA Splicing - Major Pathway
R-CEL-72187 mRNA 3'-end processing

Names & Taxonomyi

Protein namesi
Submitted name:
U2AF splicing factorImported
Gene namesi
Name:uaf-2Imported
ORF Names:CELE_Y116A8C.35Imported, Y116A8C.35Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY116A8C.35a ; CE23341 ; WBGene00006698 ; uaf-2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiQ9U2U0
PaxDbiQ9U2U0
PeptideAtlasiQ9U2U0

Expressioni

Gene expression databases

BgeeiWBGene00006698
ExpressionAtlasiQ9U2U0 baseline and differential

Interactioni

Protein-protein interaction databases

DIPiDIP-26717N
IntActiQ9U2U0, 3 interactors
STRINGi6239.Y116A8C.35.2

Structurei

3D structure databases

ProteinModelPortaliQ9U2U0
SMRiQ9U2U0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 48C3H1-typeInterPro annotationAdd BLAST29
Domaini88 – 156RRMInterPro annotationAdd BLAST69
Domaini158 – 185C3H1-typeInterPro annotationAdd BLAST28

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri20 – 48C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri158 – 185C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2202 Eukaryota
ENOG410Z5PX LUCA
GeneTreeiENSGT00530000063193
HOGENOMiHOG000178619
InParanoidiQ9U2U0
KOiK12836
OMAiKEAICRQ
OrthoDBiEOG091G0CUI
PhylomeDBiQ9U2U0

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR009145 U2AF_small
IPR000571 Znf_CCCH
PANTHERiPTHR12620 PTHR12620, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF00642 zf-CCCH, 1 hit
PRINTSiPR01848 U2AUXFACTOR
SMARTiView protein in SMART
SM00361 RRM_1, 1 hit
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
PS50103 ZF_C3H1, 2 hits

Sequencei

Sequence statusi: Complete.

Q9U2U0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYGDGLSGA EYLASIYGTE KDKVNCSFFF KTGACRHGDK CSRAHHTPTF
60 70 80 90 100
SPTVVLKNFY HNPVVDVRQA DAFDKVGKRN DQEQRYFDDF YEEVFVEMER
110 120 130 140 150
KYGEVEEINV CENIGEHMVG NVYVKFMKEE DAEKAKNDLN NRWFNGQPIY
160 170 180 190 200
AELCPVTDFR ESRCRQHEVT TCSKGGFCNF MHLKAISAEL GDRLYGRRGR
210 220 230 240 250
RADAAGHYPS QRGGSGGGGG GGGGGGYGSG GGWGGGGGGR DRDRGGWGGG
260 270 280
GGGRGYGGGG GGGGYGYGGG GGGRRRSRSR DRRRY
Length:285
Mass (Da):30,856
Last modified:May 1, 2000 - v1
Checksum:iE2B932629653C040
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAB55137.1
PIRiT31503
RefSeqiNP_503036.1, NM_070635.3
UniGeneiCel.5051

Genome annotation databases

EnsemblMetazoaiY116A8C.35a.1; Y116A8C.35a.1; WBGene00006698
Y116A8C.35a.2; Y116A8C.35a.2; WBGene00006698
GeneIDi178489
KEGGicel:CELE_Y116A8C.35
UCSCiY116A8C.35 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ9U2U0_CAEEL
AccessioniPrimary (citable) accession number: Q9U2U0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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