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Q9U2T9

- Q9U2T9_CAEEL

UniProt

Q9U2T9 - Q9U2T9_CAEEL

Protein
Submitted name:

Protein ITSN-1, isoform a

Gene

itsn-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 2 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. protein binding Source: IntAct

    Enzyme and pathway databases

    SignaLinkiQ9U2T9.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein ITSN-1, isoform aImported
    Gene namesi
    Name:itsn-1Imported
    ORF Names:CELE_Y116A8C.36Imported, Y116A8C.36Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome IV

    Organism-specific databases

    WormBaseiY116A8C.36a; CE42665; WBGene00006405; itsn-1.

    Subcellular locationi

    GO - Cellular componenti

    1. endocytic vesicle Source: WormBase
    2. plasma membrane Source: WormBase
    3. synaptic vesicle Source: WormBase

    PTM / Processingi

    Proteomic databases

    PaxDbiQ9U2T9.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    figl-1O162993EBI-2414252,EBI-320880
    num-1Q9XTY63EBI-2414252,EBI-495781
    unc-11Q9XZI63EBI-2414252,EBI-311866

    Protein-protein interaction databases

    IntActiQ9U2T9. 58 interactions.
    STRINGi6239.Y116A8C.36.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9U2T9.
    SMRiQ9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 5 SH3 domains.UniRule annotation

    Keywords - Domaini

    SH3 domainUniRule annotation

    Phylogenomic databases

    eggNOGiNOG301764.
    GeneTreeiENSGT00750000117388.
    HOGENOMiHOG000199523.
    InParanoidiQ9U2T9.
    OMAiKSTIDGM.
    PhylomeDBiQ9U2T9.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00018. SH3_1. 2 hits.
    PF07653. SH3_2. 2 hits.
    PF14604. SH3_9. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 5 hits.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 5 hits.
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9U2T9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNPWEVSDA EYQKNFAMFG QLTGGQPFMD AVTARNALMR SNLPTQVLSQ     50
    IWALSDLDKD GRLDIREYSI AMRLALNCLA GIPIPPQLPP SLLVVPARNA 100
    PPTWPGSRHG SVDYSQTLPP AIDRRMSQSY IPSAPVSIAG TPSSRHNSIS 150
    AGSPLNNDRN VFEGRQLENW AIPHHNKLKY SQLFNALDKE RLGSLSSQVG 200
    RSALGLSGLP TNVLAHIWFL SDVNKDGKLS VDEYAISQYM IEMFKSGFAL 250
    PKITPLELVR MCGISSRSAN NTPELEPGAE PPQKSPAPKT FEDKRQDNLS 300
    KGQAELERRR RVLEEEEQRR RAEVEKKERE EEAKKNRERQ EKERQAEVER 350
    QAELERQRII EAQREEEEKK RRLEMERRRE EDEKMRKVQM EKAKVKQMQN 400
    QKQQENERLA QRQQREKTLQ FQLQALDEKV IDVEVDIGKA KEAVAEVTGF 450
    IERMRSTRDE KVARIKELQE TNQKTAIESQ ELGHQLLQKQ SAHKETTQRK 500
    SELEALRRKR DAIRKAIEDA ALELSTEKEK SYNQTEILKT NKEKYKTDVY 550
    SKLVAKREEY RNSFELLVHA QTHARSKIGE FEAKSAPASA APAPAPAPAP 600
    TTTNGFPANF NDAFGEFDKT DASQRFDADF GATSTADPFA QIAQAPAHSK 650
    GAVDQSAFNI HDTYKCRALF AFEARSEDEL SFEPGDVIIV FQSHAAEPGW 700
    RAGQLREKVG WFPEAFVEAI AAVPTPGGDP PIQNMPPNMT PSSSVDQIGV 750
    KAARKAEIAA AMGLTEGGAP PASSAPAAAA VISQCIAQFQ WRARNEEDLS 800
    FAKGDTIEVL EKQEMKWKGR NPAGEIGWFP KSYVKEVGAT TSTTTPIVSP 850
    SKASAGAPGA AAGAQYDVVP SDVTLQASET APQQQLYTVI YDFEAVETTD 900
    LALHVGDTIL VLEKNDEWWK GRCNGREGIF PANYVEISVQ QAGDPTPPTQ 950
    APTPAAPPTV LCEAKVVVDF VASAPNQLGI KVGEIVKIRE KSAAGWWEGE 1000
    LIRNGKPIAG WFPGEYVKVL EEAASPATRA TAVYDYEASQ PDELGFKTGD 1050
    VIIVTDKSEA EWWSGHREQD PSKSGLFPSN YVQQQ 1085
    Length:1,085
    Mass (Da):120,492
    Last modified:July 22, 2008 - v2
    Checksum:i256F5E87CC3898CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL117204 Genomic DNA. Translation: CAB55138.2.
    RefSeqiNP_001255927.1. NM_001268998.1.
    UniGeneiCel.11645.

    Genome annotation databases

    EnsemblMetazoaiY116A8C.36a.1; Y116A8C.36a.1; WBGene00006405.
    Y116A8C.36a.2; Y116A8C.36a.2; WBGene00006405.
    GeneIDi178491.
    KEGGicel:CELE_Y116A8C.36.
    UCSCiY116A8C.36. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL117204 Genomic DNA. Translation: CAB55138.2 .
    RefSeqi NP_001255927.1. NM_001268998.1.
    UniGenei Cel.11645.

    3D structure databases

    ProteinModelPortali Q9U2T9.
    SMRi Q9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q9U2T9. 58 interactions.
    STRINGi 6239.Y116A8C.36.

    Proteomic databases

    PaxDbi Q9U2T9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Y116A8C.36a.1 ; Y116A8C.36a.1 ; WBGene00006405 .
    Y116A8C.36a.2 ; Y116A8C.36a.2 ; WBGene00006405 .
    GeneIDi 178491.
    KEGGi cel:CELE_Y116A8C.36.
    UCSCi Y116A8C.36. c. elegans.

    Organism-specific databases

    CTDi 178491.
    WormBasei Y116A8C.36a ; CE42665 ; WBGene00006405 ; itsn-1.

    Phylogenomic databases

    eggNOGi NOG301764.
    GeneTreei ENSGT00750000117388.
    HOGENOMi HOG000199523.
    InParanoidi Q9U2T9.
    OMAi KSTIDGM.
    PhylomeDBi Q9U2T9.

    Enzyme and pathway databases

    SignaLinki Q9U2T9.

    Miscellaneous databases

    NextBioi 901344.
    PROi Q9U2T9.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00018. SH3_1. 2 hits.
    PF07653. SH3_2. 2 hits.
    PF14604. SH3_9. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 5 hits.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 5 hits.
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ9U2T9_CAEEL
    AccessioniPrimary (citable) accession number: Q9U2T9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 107 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3