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Q9U2T9

- Q9U2T9_CAEEL

UniProt

Q9U2T9 - Q9U2T9_CAEEL

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Protein
Submitted name:

Protein ITSN-1, isoform a

Gene
itsn-1, CELE_Y116A8C.36, Y116A8C.36
Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. protein binding Source: IntAct
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ9U2T9.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein ITSN-1, isoform aImported
Gene namesi
Name:itsn-1Imported
ORF Names:CELE_Y116A8C.36Imported, Y116A8C.36Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiY116A8C.36a; CE42665; WBGene00006405; itsn-1.

Subcellular locationi

GO - Cellular componenti

  1. endocytic vesicle Source: WormBase
  2. plasma membrane Source: WormBase
  3. synaptic vesicle Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9U2T9.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
figl-1O162993EBI-2414252,EBI-320880
num-1Q9XTY63EBI-2414252,EBI-495781
unc-11Q9XZI63EBI-2414252,EBI-311866

Protein-protein interaction databases

IntActiQ9U2T9. 58 interactions.
STRINGi6239.Y116A8C.36.

Structurei

3D structure databases

ProteinModelPortaliQ9U2T9.
SMRiQ9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.

Family & Domainsi

Sequence similaritiesi

Contains 5 SH3 domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiNOG301764.
GeneTreeiENSGT00750000117388.
HOGENOMiHOG000199523.
InParanoidiQ9U2T9.
OMAiKSTIDGM.
PhylomeDBiQ9U2T9.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00018. SH3_1. 2 hits.
PF07653. SH3_2. 2 hits.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 5 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9U2T9-1 [UniParc]FASTAAdd to Basket

« Hide

MTNPWEVSDA EYQKNFAMFG QLTGGQPFMD AVTARNALMR SNLPTQVLSQ     50
IWALSDLDKD GRLDIREYSI AMRLALNCLA GIPIPPQLPP SLLVVPARNA 100
PPTWPGSRHG SVDYSQTLPP AIDRRMSQSY IPSAPVSIAG TPSSRHNSIS 150
AGSPLNNDRN VFEGRQLENW AIPHHNKLKY SQLFNALDKE RLGSLSSQVG 200
RSALGLSGLP TNVLAHIWFL SDVNKDGKLS VDEYAISQYM IEMFKSGFAL 250
PKITPLELVR MCGISSRSAN NTPELEPGAE PPQKSPAPKT FEDKRQDNLS 300
KGQAELERRR RVLEEEEQRR RAEVEKKERE EEAKKNRERQ EKERQAEVER 350
QAELERQRII EAQREEEEKK RRLEMERRRE EDEKMRKVQM EKAKVKQMQN 400
QKQQENERLA QRQQREKTLQ FQLQALDEKV IDVEVDIGKA KEAVAEVTGF 450
IERMRSTRDE KVARIKELQE TNQKTAIESQ ELGHQLLQKQ SAHKETTQRK 500
SELEALRRKR DAIRKAIEDA ALELSTEKEK SYNQTEILKT NKEKYKTDVY 550
SKLVAKREEY RNSFELLVHA QTHARSKIGE FEAKSAPASA APAPAPAPAP 600
TTTNGFPANF NDAFGEFDKT DASQRFDADF GATSTADPFA QIAQAPAHSK 650
GAVDQSAFNI HDTYKCRALF AFEARSEDEL SFEPGDVIIV FQSHAAEPGW 700
RAGQLREKVG WFPEAFVEAI AAVPTPGGDP PIQNMPPNMT PSSSVDQIGV 750
KAARKAEIAA AMGLTEGGAP PASSAPAAAA VISQCIAQFQ WRARNEEDLS 800
FAKGDTIEVL EKQEMKWKGR NPAGEIGWFP KSYVKEVGAT TSTTTPIVSP 850
SKASAGAPGA AAGAQYDVVP SDVTLQASET APQQQLYTVI YDFEAVETTD 900
LALHVGDTIL VLEKNDEWWK GRCNGREGIF PANYVEISVQ QAGDPTPPTQ 950
APTPAAPPTV LCEAKVVVDF VASAPNQLGI KVGEIVKIRE KSAAGWWEGE 1000
LIRNGKPIAG WFPGEYVKVL EEAASPATRA TAVYDYEASQ PDELGFKTGD 1050
VIIVTDKSEA EWWSGHREQD PSKSGLFPSN YVQQQ 1085
Length:1,085
Mass (Da):120,492
Last modified:July 22, 2008 - v2
Checksum:i256F5E87CC3898CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117204 Genomic DNA. Translation: CAB55138.2.
RefSeqiNP_001255927.1. NM_001268998.1.
UniGeneiCel.11645.

Genome annotation databases

EnsemblMetazoaiY116A8C.36a.1; Y116A8C.36a.1; WBGene00006405.
Y116A8C.36a.2; Y116A8C.36a.2; WBGene00006405.
GeneIDi178491.
KEGGicel:CELE_Y116A8C.36.
UCSCiY116A8C.36. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117204 Genomic DNA. Translation: CAB55138.2 .
RefSeqi NP_001255927.1. NM_001268998.1.
UniGenei Cel.11645.

3D structure databases

ProteinModelPortali Q9U2T9.
SMRi Q9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9U2T9. 58 interactions.
STRINGi 6239.Y116A8C.36.

Proteomic databases

PaxDbi Q9U2T9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y116A8C.36a.1 ; Y116A8C.36a.1 ; WBGene00006405 .
Y116A8C.36a.2 ; Y116A8C.36a.2 ; WBGene00006405 .
GeneIDi 178491.
KEGGi cel:CELE_Y116A8C.36.
UCSCi Y116A8C.36. c. elegans.

Organism-specific databases

CTDi 178491.
WormBasei Y116A8C.36a ; CE42665 ; WBGene00006405 ; itsn-1.

Phylogenomic databases

eggNOGi NOG301764.
GeneTreei ENSGT00750000117388.
HOGENOMi HOG000199523.
InParanoidi Q9U2T9.
OMAi KSTIDGM.
PhylomeDBi Q9U2T9.

Enzyme and pathway databases

SignaLinki Q9U2T9.

Miscellaneous databases

NextBioi 901344.
PROi Q9U2T9.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00018. SH3_1. 2 hits.
PF07653. SH3_2. 2 hits.
PF14604. SH3_9. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 5 hits.
PROSITEi PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiQ9U2T9_CAEEL
AccessioniPrimary (citable) accession number: Q9U2T9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 22, 2008
Last modified: July 9, 2014
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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