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Q9U2T9

- Q9U2T9_CAEEL

UniProt

Q9U2T9 - Q9U2T9_CAEEL

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Protein
Submitted name:

Protein ITSN-1, isoform a

Gene

itsn-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ9U2T9.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein ITSN-1, isoform aImported
Gene namesi
Name:itsn-1Imported
ORF Names:CELE_Y116A8C.36Imported, Y116A8C.36Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiY116A8C.36a; CE42665; WBGene00006405; itsn-1.

Subcellular locationi

GO - Cellular componenti

  1. endocytic vesicle Source: WormBase
  2. plasma membrane Source: WormBase
  3. synaptic vesicle Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9U2T9.

Expressioni

Gene expression databases

ExpressionAtlasiQ9U2T9. baseline.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
figl-1O162993EBI-2414252,EBI-320880
num-1Q9XTY63EBI-2414252,EBI-495781
unc-11Q9XZI63EBI-2414252,EBI-311866

Protein-protein interaction databases

IntActiQ9U2T9. 58 interactions.
STRINGi6239.Y116A8C.36.

Structurei

3D structure databases

ProteinModelPortaliQ9U2T9.
SMRiQ9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 5 SH3 domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiNOG301764.
GeneTreeiENSGT00760000118985.
HOGENOMiHOG000199523.
InParanoidiQ9U2T9.
OMAiKSTIDGM.
PhylomeDBiQ9U2T9.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00018. SH3_1. 2 hits.
PF07653. SH3_2. 2 hits.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 5 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9U2T9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNPWEVSDA EYQKNFAMFG QLTGGQPFMD AVTARNALMR SNLPTQVLSQ
60 70 80 90 100
IWALSDLDKD GRLDIREYSI AMRLALNCLA GIPIPPQLPP SLLVVPARNA
110 120 130 140 150
PPTWPGSRHG SVDYSQTLPP AIDRRMSQSY IPSAPVSIAG TPSSRHNSIS
160 170 180 190 200
AGSPLNNDRN VFEGRQLENW AIPHHNKLKY SQLFNALDKE RLGSLSSQVG
210 220 230 240 250
RSALGLSGLP TNVLAHIWFL SDVNKDGKLS VDEYAISQYM IEMFKSGFAL
260 270 280 290 300
PKITPLELVR MCGISSRSAN NTPELEPGAE PPQKSPAPKT FEDKRQDNLS
310 320 330 340 350
KGQAELERRR RVLEEEEQRR RAEVEKKERE EEAKKNRERQ EKERQAEVER
360 370 380 390 400
QAELERQRII EAQREEEEKK RRLEMERRRE EDEKMRKVQM EKAKVKQMQN
410 420 430 440 450
QKQQENERLA QRQQREKTLQ FQLQALDEKV IDVEVDIGKA KEAVAEVTGF
460 470 480 490 500
IERMRSTRDE KVARIKELQE TNQKTAIESQ ELGHQLLQKQ SAHKETTQRK
510 520 530 540 550
SELEALRRKR DAIRKAIEDA ALELSTEKEK SYNQTEILKT NKEKYKTDVY
560 570 580 590 600
SKLVAKREEY RNSFELLVHA QTHARSKIGE FEAKSAPASA APAPAPAPAP
610 620 630 640 650
TTTNGFPANF NDAFGEFDKT DASQRFDADF GATSTADPFA QIAQAPAHSK
660 670 680 690 700
GAVDQSAFNI HDTYKCRALF AFEARSEDEL SFEPGDVIIV FQSHAAEPGW
710 720 730 740 750
RAGQLREKVG WFPEAFVEAI AAVPTPGGDP PIQNMPPNMT PSSSVDQIGV
760 770 780 790 800
KAARKAEIAA AMGLTEGGAP PASSAPAAAA VISQCIAQFQ WRARNEEDLS
810 820 830 840 850
FAKGDTIEVL EKQEMKWKGR NPAGEIGWFP KSYVKEVGAT TSTTTPIVSP
860 870 880 890 900
SKASAGAPGA AAGAQYDVVP SDVTLQASET APQQQLYTVI YDFEAVETTD
910 920 930 940 950
LALHVGDTIL VLEKNDEWWK GRCNGREGIF PANYVEISVQ QAGDPTPPTQ
960 970 980 990 1000
APTPAAPPTV LCEAKVVVDF VASAPNQLGI KVGEIVKIRE KSAAGWWEGE
1010 1020 1030 1040 1050
LIRNGKPIAG WFPGEYVKVL EEAASPATRA TAVYDYEASQ PDELGFKTGD
1060 1070 1080
VIIVTDKSEA EWWSGHREQD PSKSGLFPSN YVQQQ
Length:1,085
Mass (Da):120,492
Last modified:July 22, 2008 - v2
Checksum:i256F5E87CC3898CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117204 Genomic DNA. Translation: CAB55138.2.
RefSeqiNP_001255927.1. NM_001268998.1.
UniGeneiCel.11645.

Genome annotation databases

EnsemblMetazoaiY116A8C.36a.1; Y116A8C.36a.1; WBGene00006405.
Y116A8C.36a.2; Y116A8C.36a.2; WBGene00006405.
GeneIDi178491.
KEGGicel:CELE_Y116A8C.36.
UCSCiY116A8C.36. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117204 Genomic DNA. Translation: CAB55138.2 .
RefSeqi NP_001255927.1. NM_001268998.1.
UniGenei Cel.11645.

3D structure databases

ProteinModelPortali Q9U2T9.
SMRi Q9U2T9. Positions 18-93, 170-259, 287-547, 667-717, 768-1082.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9U2T9. 58 interactions.
STRINGi 6239.Y116A8C.36.

Proteomic databases

PaxDbi Q9U2T9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y116A8C.36a.1 ; Y116A8C.36a.1 ; WBGene00006405 .
Y116A8C.36a.2 ; Y116A8C.36a.2 ; WBGene00006405 .
GeneIDi 178491.
KEGGi cel:CELE_Y116A8C.36.
UCSCi Y116A8C.36. c. elegans.

Organism-specific databases

CTDi 178491.
WormBasei Y116A8C.36a ; CE42665 ; WBGene00006405 ; itsn-1.

Phylogenomic databases

eggNOGi NOG301764.
GeneTreei ENSGT00760000118985.
HOGENOMi HOG000199523.
InParanoidi Q9U2T9.
OMAi KSTIDGM.
PhylomeDBi Q9U2T9.

Enzyme and pathway databases

SignaLinki Q9U2T9.

Miscellaneous databases

NextBioi 901344.
PROi Q9U2T9.

Gene expression databases

ExpressionAtlasi Q9U2T9. baseline.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00018. SH3_1. 2 hits.
PF07653. SH3_2. 2 hits.
PF14604. SH3_9. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 5 hits.
PROSITEi PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ9U2T9_CAEEL
AccessioniPrimary (citable) accession number: Q9U2T9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 22, 2008
Last modified: October 29, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3