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Protein
Submitted name:

TIA-1/TIAL RNA binding protein homolog

Gene

tiar-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • determination of adult lifespan Source: WormBase
  • hyperosmotic response Source: WormBase
  • nematode larval development Source: WormBase
  • reproduction Source: WormBase
  • response to heat Source: WormBase

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TIA-1/TIAL RNA binding protein homologImported
Gene namesi
Name:tiar-2Imported
ORF Names:CELE_Y46G5A.13Imported, Y46G5A.13Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiY46G5A.13; CE21988; WBGene00012904; tiar-2.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: WormBase
  • cytoplasmic stress granule Source: WormBase
  • nucleus Source: WormBase

PTM / Processingi

Proteomic databases

EPDiQ9U2F5.
PaxDbiQ9U2F5.
PeptideAtlasiQ9U2F5.

Expressioni

Gene expression databases

BgeeiWBGene00012904.

Interactioni

Protein-protein interaction databases

IntActiQ9U2F5. 1 interactor.
STRINGi6239.Y46G5A.13.

Structurei

3D structure databases

ProteinModelPortaliQ9U2F5.
SMRiQ9U2F5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 115RRM (RNA recognition motif)InterPro annotationAdd BLAST76
Domaini132 – 210RRM (RNA recognition motif)InterPro annotationAdd BLAST79
Domaini256 – 327RRM (RNA recognition motif)InterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG0148. Eukaryota.
ENOG410XQ8U. LUCA.
GeneTreeiENSGT00870000136413.
HOGENOMiHOG000206748.
InParanoidiQ9U2F5.
KOiK13201.
OMAiGSQRHTF.
OrthoDBiEOG091G0FH8.
PhylomeDBiQ9U2F5.

Family and domain databases

InterProiView protein in InterPro
IPR000504. RRM_dom.
IPR003954. RRM_dom_euk.
PfamiView protein in Pfam
PF00076. RRM_1. 3 hits.
SMARTiView protein in SMART
SM00360. RRM. 3 hits.
SM00361. RRM_1. 3 hits.
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiView protein in PROSITE
PS50102. RRM. 3 hits.

Sequencei

Sequence statusi: Complete.

Q9U2F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSFYTGGG EDGDGFNPRV HARIAEREGF QLASGSEDPR TLFVANLDPA
60 70 80 90 100
ITDEFLATLF NQIGAVMKAK IIFEGLNDPY AFVEFSDHNQ ATLALQSHNG
110 120 130 140 150
RELLEKEMHV TWAFEPREPG ENRSKPETSR HFHVFVGDLC SEIDSTKLRE
160 170 180 190 200
AFVKFGEVSE AKIIRDNNTN KGKGYGFVSY PRREDAERAI DEMNGAWLGR
210 220 230 240 250
RTIRTNWATR KPDEDGERGG DRGDRRGGGG GGRDRYHNQS EKTYDEIFNQ
260 270 280 290 300
AAADNTSVYV GNIANLGEDE IRRAFDRFGP INEVRTFKIQ GYAFVKFETK
310 320 330 340 350
ESAARAIVQM NNADIGGQIV RCSWGKSGDS GKPSERGSGG GGGSGNYGYG
360 370 380 390 400
YGNSGGGGGS GGPGNSQFSN FNQRPPPSGN GGSGGGSGGQ NNQYWQYYSQ
410 420 430
YYNNPHLMQQ WNNYWQKDGP PPPPAAAASS TGGN
Length:434
Mass (Da):47,331
Last modified:May 1, 2000 - v1
Checksum:iC55C76248C660C9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAB60356.1.
RefSeqiNP_496718.1. NM_064317.1.
UniGeneiCel.14057.

Genome annotation databases

EnsemblMetazoaiY46G5A.13; Y46G5A.13; WBGene00012904.
GeneIDi174909.
KEGGicel:CELE_Y46G5A.13.
UCSCiY46G5A.13. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9U2F5_CAEEL
AccessioniPrimary (citable) accession number: Q9U2F5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported