Unreviewed, UniProtKB/TrEMBL Q9U1I3 (Q9U1I3_DROME)

Names and origin

Protein names

Submitted name:
    GRAAL protein EMBL CAB64652.1

Gene names

Name:	Tequila FlyBase FBgn0023479
Synonyms:	graal EMBL CAB64652.1
ORF Names:	CG4821 FlyBase FBgn0023479

Organism

Drosophila melanogaster (Fruit fly) EMBL CAB64652.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1462 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
PTM	Disulfide bond Spearmint SPM001190
Gene Ontology (GO)
Biological process	chitin metabolic process Inferred from electronic annotation. Source: InterPro long-term memory Inferred from mutant phenotype. Source: FlyBase proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro membrane Inferred from electronic annotation. Source: InterPro
Molecular function	chitin binding Inferred from electronic annotation. Source: InterPro scavenger receptor activity Inferred from electronic annotation. Source: InterPro serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9U1I3-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: E3AC494FE140F37A	FASTA	1,462	161,445
	10 20 30 40 50 60 MMAKWLLGLW LAILLVDVSV ESLLIISNCR PGAKAYRSGS GYHSEQSEPV GLSATGNAHS 70 80 90 100 110 120 SYGGDQQQPI YHRDSACPPH FTGLVAYPHD CHRYVNCFDG SPTIQTCSPG TLFNDRTQVC 130 140 150 160 170 180 DHPSNVVCPS AESASTRLGR LRQLDSEPKC QPGVNGLQPH PSDCSKFLNC ANGQAFIMDC 190 200 210 220 230 240 APGTAFSPAS LVCVHKDLAK CGSGTGAVRD DTSGTDNRQS KSYETSGRDQ FGNRYTTRTT 250 260 270 280 290 300 TTTRVIGDRW TDMNMQRPSG VGVEQNPHHH HHGYNPGWSG QETSYVQRGP TQSTLYVEGS 310 320 330 340 350 360 LQPNRNYPTN KTPLAPMAPT NTGGVYYGQP VEDKENVPSR QNYSRRIDYG SPGNGWKPMP 370 380 390 400 410 420 PLDPLGGQQP LNLDYSPHSP GAKEPQSQDS LPGQKPINLD YDEEPIPQYP HNGLPPYPGS 430 440 450 460 470 480 PPRFYPDQLP SGSKPIGRQQ PVESSRDATG FPDQQKPLDP DNRLHGSKVP PRHSPNPGYP 490 500 510 520 530 540 LYNESNLYGG LLPPKPDSPV NTTPTPTPNP SSSQAPTPHL ANRLHTFPIY PPVDNKTSLR 550 560 570 580 590 600 NPIQPHYSPS YAGIAHSRDA PWAKVPVTST TPAQDPDPFN PELDEPFYDD VDFLSTTVRN 610 620 630 640 650 660 VLVPPPFDHK FYSPQSTNPS INRNQSASGP NSQAAIKEAL KLMLRPYFNH SGNAQEQLAQ 670 680 690 700 710 720 QAESAIVSVI SKPSTTTTTT PRPTSKTPKT DPDFDAELIK AGEQESLDSV DDDYVFPDAR 730 740 750 760 770 780 ETSRTEQTLD PSTTYASTNF QRSTRRAELD PDTLTATTMK TNWHAPGHSR DYHRRHPNLP 790 800 810 820 830 840 DPFTEHHPNS SPHQHQHHHR HPHEHSADFH LRHPGLPNPF PLKNETPQHQ DLNDDWDLLP 850 860 870 880 890 900 NSNAEEVTPK LATRSSFNTQ CDFDCGNGQC LKKEEICDGK KNCPNGKDEA NCPPSDYEVR 910 920 930 940 950 960 LSGGESPNMG RIEVKANGQW GYVCDDKFGL KDADVVCREL GFQMGAQEVR GSSFYAPPNQ 970 980 990 1000 1010 1020 DFNYLMDEVE CHGNETKLGQ CAFKGWGVHN CGVDEVAGVT CKVPVMKCPN NYWLCHTSKE 1030 1040 1050 1060 1070 1080 CIPPAFVCDN TPDCADKSDE CAAVCQAPVQ YRLEGGRNSN EGRLEVKHHG VWGSVCDDDF 1090 1100 1110 1120 1130 1140 NLKSAQVACN SMGFFGPAKI EKNIFGNSNG PIWLDQVMCF GNETSIDQCN HWNWGEHNCN 1150 1160 1170 1180 1190 1200 HTEDVALHCS AGPPPRSQRY SQTQIKGGRS LGRETTPKTY SQIGLWERSS KAVHTPRRCG 1210 1220 1230 1240 1250 1260 IFKDDLTDEY AHREERVVRG NVAQRGRHPW QATIRTRGRG GISSHWCGAV VISKRHLLTA 1270 1280 1290 1300 1310 1320 AHCLYGSPKG AYFVRVGDHY ANIAESSEVD SFIENWYLHE NFRKGTHMNN DIALVVLKTP 1330 1340 1350 1360 1370 1380 LKFSDYVQPI CLPDKNAELV EDRKCTISGW GSIKSGVSTP AQVLGSAELP ILADHVCKQS 1390 1400 1410 1420 1430 1440 NVYGSAMSEG MFCAGSMDES VDACEGDSGG PLVCSDDDGE TLYGLISWGQ HCGFKNRPGV 1450 1460 YVRVNHYIDW IYEKINESLL RF

References

[1]	"graal: a Drosophila gene coding for several mosaic serine proteases." Munier A.I., Medzhitov R., Janeway C.A. Jr, Doucet D., Capovilla M., Lagueux M. Insect Biochem. Mol. Biol. 34:1025-1035(2004) [PubMed: 15475297] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ251802 Genomic DNA. Translation: CAB64652.1.
3D structure databases
HSSP	HSSP built from PDB template 1EZX based on UniProtKB P00760.
ModBase	Search...
Protein family/group databases
CAZy	CBM14. Carbohydrate-Binding Module Family 14.
MEROPS	S01.112. S01.461.
Proteomic databases
PRIDE	Q9U1I3.
Genome annotation databases
Ensembl	FBgn0023479. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0023479. Tequila.
Gene expression databases
ArrayExpress	Q9U1I3.
Family and domain databases
InterPro	IPR020003. ATPase_F1/V1/A1_a/bsu_AS. IPR002557. Chitin-bd_peritrophin-A. IPR002172. LDL_rcpt_classA_cys-rich. IPR018114. Peptidase_S1/S6_AS. IPR001254. Peptidase_S1_S6. IPR001190. Srcr_rcpt. IPR017448. Srcr_rcpt-rel. [Graphical view]
Pfam	PF01607. CBM_14. 2 hits. PF00057. Ldl_recept_a. 1 hit. PF00530. SRCR. 2 hits. PF00089. Trypsin. 1 hit. [Graphical view]
PRINTS	PR00261. LDLRECEPTOR.
SMART	SM00494. ChtBD2. 2 hits. SM00192. LDLa. 2 hits. SM00202. SR. 2 hits. SM00020. Tryp_SPc. 1 hit. [Graphical view]
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. Uncertain. PS50940. CHIT_BIND_II. 2 hits. PS01209. LDLRA_1. 1 hit. PS50068. LDLRA_2. 2 hits. PS00420. SRCR_1. 2 hits. PS50287. SRCR_2. 2 hits. PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9U1I3_DROME

Accession

Primary (citable) accession number: Q9U1I3

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)