Q9U1I2 (Q9U1I2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GRAAL protein EMBL CAB64653.1

Gene names

Name:	Tequila FlyBase FBgn0023479
Synonyms:	graal EMBL CAB64653.1
ORF Names:	CG4821 FlyBase FBgn0023479

Organism

Drosophila melanogaster (Fruit fly) EMBL CAB64653.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1449 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
PTM	Disulfide bond SAAS SAAS023415
Gene Ontology (GO)
Biological process	chitin metabolic process Inferred from electronic annotation. Source: InterPro long-term memory Inferred from mutant phenotype. Source: FlyBase proteolysis Non-traceable author statement. Source: FlyBase
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro membrane Inferred from electronic annotation. Source: InterPro
Molecular function	chitin binding Inferred from electronic annotation. Source: InterPro scavenger receptor activity Inferred from electronic annotation. Source: InterPro serine-type endopeptidase activity Non-traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9U1I2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: F3BC806543CAB6ED	FASTA	1,449	160,046
	10 20 30 40 50 60 MMAQWLLGLW LAILLVHRPG AKAYRSGSGY HSEQSEPVGL SATGNAHSSY GGDQQQPIYH 70 80 90 100 110 120 RDSACPPHFT GLVAYPHDCH RYVNCFDGSP TIQTCSPGTL FNDRTQVCDH PSNVVCPSAE 130 140 150 160 170 180 SASTRLGRLR QLDSEPKCQP GVNGLQPHPS DCSKFLNCAN GQAFIMDCAP GTAFSPASLV 190 200 210 220 230 240 CVHKDLAKCG SGTGAVRDDT SGTDNRQSKS YETSGRDQFG NRYTTRTTTT TRVIGDRWTD 250 260 270 280 290 300 MNMQRPSGVG VEQNPHHHHH GYNPGWSGQE TSYVQRGPTQ STLYVEGSLQ PNRNYPTNKT 310 320 330 340 350 360 PLAPMAPTNT GGVYYGQPVE DKENVPSRQN YSRRIDYGSP GNGWKPMPPL DPLGGQQPLN 370 380 390 400 410 420 LDYSPHSPGA KEPQSQDSLP GQKPINLDYD EEPIPQYLHN GLPPYPGSPP RFYPDQLPSG 430 440 450 460 470 480 SKPIGRQQPV ESSPDASGYP DQQKPLDPDN GLHGSKVPPR HSPNPGYPLY NESNLYGGLL 490 500 510 520 530 540 PPKPDSPNTT PTPTPNPSSS QAPTPQLANR LHTFPIYPPV DNKTSLRNPI QPHYSPSYAG 550 560 570 580 590 600 IAHSRDAPWA KVPVTSTTPA QDPDPFNPEL DEPFYDDVDF LTTTVRNVLV PPPFDHKFYS 610 620 630 640 650 660 PQSTNPSINR NQSASGPNSQ AAIKEALKLM LRPYFNHSGN AQEQLAQQAE SAIVSVISKP 670 680 690 700 710 720 STTTTTTPRP TSKTPKTDPD FDAELIKAGE QESLDSVDDD YVFPDARETS RTEQTLDPST 730 740 750 760 770 780 TYASTNFQRS TRRAELDPDT LTATTMKTNW HAPGHSRDYH RRHPNLPDPF TEHHPNSSPH 790 800 810 820 830 840 QHQHHHRHPH EHSADFHLRH PELPNPFPLK NETPQHQDLN DDWDLLPNSN AEEVTPKLAT 850 860 870 880 890 900 RSSFNTQCDF DCGNGQCLKK EEICDGKKNC PNGKDEANCP PSDYEVRLSG GESPNMGRIE 910 920 930 940 950 960 VKANGQWGYV CDDKFGLKDA DVVCRELGFQ MGAQEVRGSS FYAPPNQDFN YLMDEVECHG 970 980 990 1000 1010 1020 NETKLGQCAF KGWGVHNCGV DEVAGVTCKV PVMKCPNNYW LCHTSKECIP PAFVCDNTPD 1030 1040 1050 1060 1070 1080 CADKSDECAA VCQAPVQYRL EGGRNSNEGR LEVKHHGVWG SVCDDDFNLK SAQVACNSMG 1090 1100 1110 1120 1130 1140 FFGPAKIEKN IFGNSNGPIW LDQVMCFGNE TSIDQCNHWN WGEHNCNHTE DVALHCSAGP 1150 1160 1170 1180 1190 1200 PPRSQRYSQT QIKGGRSLGR ETTPKTYSQI GLWERSSKAV HTPRRCGIFK DDLTDEYAHR 1210 1220 1230 1240 1250 1260 EERVVRGNVA QRGRHPWQAT IRTRGRGGIS SHWCGAVVIS KRHLLTAAHC LYGSPKGAYF 1270 1280 1290 1300 1310 1320 VRVGDHYANI AESSEVDSFI ENWYLHENFR KGTHMNNDIA LVVLKTPLKF SDYVQPICLP 1330 1340 1350 1360 1370 1380 DKNAELVEDR KCTISGWGSI KSGVSTPAQV LGSAELPILA DHVCKQSNVY GSAMSEGMFC 1390 1400 1410 1420 1430 1440 AGSMDESVDA CEGDSGGPLV CSDDDGETLY GLISWGQHCG FKNRPGVYVR VNHYIDWIYE KINESLLRF

References

[1]	"graal: a Drosophila gene coding for several mosaic serine proteases." Munier A.I., Medzhitov R., Janeway C.A. Jr, Doucet D., Capovilla M., Lagueux M. Insect Biochem. Mol. Biol. 34:1025-1035(2004) [PubMed: 15475297] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ251803 mRNA. Translation: CAB64653.1.
3D structure databases
HSSP	HSSP built from PDB template 1EZX based on UniProtKB P00760.
ProteinModelPortal	Q9U1I2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9U1I2.
Protein family/group databases
CAZy	CBM14. Carbohydrate-Binding Module Family 14.
MEROPS	S01.461.
Proteomic databases
PRIDE	Q9U1I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0023479. Tequila.
Phylogenomic databases
InParanoid	Q9U1I2.
Gene expression databases
ArrayExpress	Q9U1I2.
Bgee	Q9U1I2.
Family and domain databases
InterPro	IPR002557. Chitin-bd_dom. IPR023415. LDLR_class-A_CS. IPR002172. LDrepeatLR_classA_rpt. IPR009003. Pept_cys/ser_Trypsin-like. IPR018114. Peptidase_S1/S6_AS. IPR001254. Peptidase_S1_S6. IPR001314. Peptidase_S1A. IPR001190. Srcr_rcpt. IPR017448. Srcr_rcpt-rel. [Graphical view]
Gene3D	G3DSA:2.170.140.10. Chitin-bd_dom. 2 hits. G3DSA:4.10.400.10. LDL_rcpt_classA_cys-rich. 2 hits.
Pfam	PF01607. CBM_14. 2 hits. PF00057. Ldl_recept_a. 1 hit. PF00530. SRCR. 2 hits. PF00089. Trypsin. 1 hit. [Graphical view]
PRINTS	PR00722. CHYMOTRYPSIN. PR00258. SPERACTRCPTR.
SMART	SM00494. ChtBD2. 2 hits. SM00192. LDLa. 2 hits. SM00202. SR. 2 hits. SM00020. Tryp_SPc. 1 hit. [Graphical view]
SUPFAM	SSF57625. Chitin_bind_PerA. 2 hits. SSF57424. LDL_rcpt_classA_cys-rich. 2 hits. SSF50494. Pept_Ser_Cys. 1 hit. SSF56487. Srcr_receptor. 2 hits.
PROSITE	PS50940. CHIT_BIND_II. 2 hits. PS01209. LDLRA_1. 1 hit. PS50068. LDLRA_2. 2 hits. PS00420. SRCR_1. 2 hits. PS50287. SRCR_2. 2 hits. PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9U1I2_DROME

Accession

Primary (citable) accession number: Q9U1I2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)