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Protein

Mite allergen Lep d 7

Gene
N/A
Organism
Lepidoglyphus destructor (Storage mite) (Glycyphagus destructor)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite allergen Lep d 7
Alternative name(s):
Allergen: Lep d 7
OrganismiLepidoglyphus destructor (Storage mite) (Glycyphagus destructor)
Taxonomic identifieri36936 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataGlycyphagoideaGlycyphagidaeLepidoglyphus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3351. Lep d 7.0101.
445. Lep d 7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 216197Mite allergen Lep d 7PRO_0000001186Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the mite group 7 allergen family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR020234. Mite_allergen_group-7.
[Graphical view]
PfamiPF16984. Grp7_allergen. 1 hit.
[Graphical view]
ProDomiPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9U1G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQYLAIAVIV ALAGLSAAAH KPAYYDDNMA NQMVDQIVKS LTTKKELDPF
60 70 80 90 100
KIEQTKVPID KKIGLIHIKG SATIKNAVIT GLSHISRRGD AKIDTDGGAF
110 120 130 140 150
AATLKLGDKN IRIKTDLHLD LGKIIHPNLK FEGHIGDIDM KLKLKLDAEG
160 170 180 190 200
KPSLDQFEID EFEQVELFIH GLGPLDPLVD VIADSFVKYF NPQARKLVTD
210
MLKPILVEEI KKLKLN
Length:216
Mass (Da):23,916
Last modified:May 1, 2000 - v1
Checksum:i59E71EAF05B4685E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271058 mRNA. Translation: CAB65963.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271058 mRNA. Translation: CAB65963.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3351. Lep d 7.0101.
445. Lep d 7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR020234. Mite_allergen_group-7.
[Graphical view]
PfamiPF16984. Grp7_allergen. 1 hit.
[Graphical view]
ProDomiPD037435. Mite_group-7_allergen. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of three new allergens from the dust mite Lepidoglyphus destructor using phage surface display technology."
    Eriksson T.L.J., Rasool O., Huecas S., Whitley P., Crameri R., Appenzeller U., Gafvelin G., van Hage-Hamsten M.
    Eur. J. Biochem. 268:287-294(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiALL7_LEPDS
AccessioniPrimary (citable) accession number: Q9U1G2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: May 1, 2000
Last modified: November 11, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.