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Protein
Submitted name:

Replication protein A1, large subunit

Gene

PF3D7_0409600

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • DNA-dependent DNA replication Source: GeneDB
  • DNA replication Source: GeneDB
  • regulation of DNA metabolic process Source: GeneDB

Enzyme and pathway databases

ReactomeiR-PFA-110320. Translesion Synthesis by POLH.
R-PFA-3108214. SUMOylation of DNA damage response and repair proteins.

Names & Taxonomyi

Protein namesi
Submitted name:
Replication protein A1, large subunitImported
Gene namesi
ORF Names:PF3D7_0409600Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0409600.

Interactioni

Protein-protein interaction databases

IntActiQ9U0J0. 4 interactors.
MINTiMINT-1572664.

Structurei

3D structure databases

ProteinModelPortaliQ9U0J0.
SMRiQ9U0J0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini697 – 781OBInterPro annotationAdd BLAST85
Domaini805 – 905REPA_OB_2InterPro annotationAdd BLAST101
Domaini966 – 1117Rep_fac-A_CInterPro annotationAdd BLAST152

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili938 – 958Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiQ9U0J0.
KOiK07466.
OMAiMNDGILM.

Family and domain databases

CDDicd04476. RPA1_DBD_C. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
IPR013955. Rep_factor-A_C.
IPR031657. REPA_OB_2.
PfamiView protein in Pfam
PF08646. Rep_fac-A_C. 1 hit.
PF16900. REPA_OB_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
SUPFAMiSSF50249. SSF50249. 3 hits.

Sequencei

Sequence statusi: Complete.

Q9U0J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSKNEEILS KATPNFIYKF FTEPNSQESL KWLNGEINLI CFSQMNAGAN
60 70 80 90 100
QTFLKVIDGS IPPQYYAIVH LGIEENNSTI SYVKKIISIE NFSITNYYGK
110 120 130 140 150
LFILAKKVTV YLNIDHFDIE DLFKKYHLQS ISYFLLNSKN ENNSRENYSR
160 170 180 190 200
IVKDSNNNMN NVNNVNNVNN MNNMNSMNSV NNMNSMNSMN NSTHNVGSSN
210 220 230 240 250
GGAGGYNNRD DNKLRENYTH SNDDNINHTN IKDNYYYSRD NNYHNNNNIN
260 270 280 290 300
NSSSSRGEKW EQVRDNYKSN EYFNNNGKAY NHNVHNRQNS EHIMKENNNK
310 320 330 340 350
NFTTPIHMNE DNRIDKQQNY MDNNNNNNMD KPNRGKFVYK ENPNIPNYTN
360 370 380 390 400
VNDYESKNNL HKPFPVQKSA SAYKGPSEYS EYNRNNMCYE NNSPGNEAYN
410 420 430 440 450
KNSRAYINKN NYDNNNNNNN NYYYYHHHNN MNTNSRQATN NQPYDYNNHN
460 470 480 490 500
RDYDNKNVNK YSDGIKDNSC YNKNEESSKM YMNSNCLPHT TSIVKLNRCD
510 520 530 540 550
ESLHERYFSI DNNNNMNNMS NVNNMSNVNN VNNVNNVNNV NNVNNVNNVN
560 570 580 590 600
NVNNVSNNNS VIMDHPSGNY NHENDPNNHH NYNNHNNYHT YDRHVNPSNN
610 620 630 640 650
HQHYNNKDEY TYTNNEDCHL KIRKDDMGSN QESRDYNYYD ENSMDNIMKK
660 670 680 690 700
DEKILKDKTL NRNNRKITPY QSNAVIKMND GILMQINKLS QYSSKWIIKA
710 720 730 740 750
RVQSKDNIRR YTSGSKEGKV FNIELCDEDG EIKANFFGKA VDKWFDFIEV
760 770 780 790 800
GKIYKISKGM IKVANKKFNT LNHDYEITLD ENSLIEILDE ENENIPKYNY
810 820 830 840 850
NFISIDNIKN MNTGSFVDII AVVLNYQEKM QIFVKKTGQY KDKRDVTLID
860 870 880 890 900
ESFDTIQVTL WEKNATIIDE MNLRDNCIVC FKYLKIGEWQ GKKLESHART
910 920 930 940 950
KIEINPDNIE KAYILKNWWI HNKKMICNSI NLSSNYINIE TQKTIQEIKK
960 970 980 990 1000
NVNLVNEEAL SGKGIMFTTY GFIDQIYNNM PVYSACPDCN KKMISNSVDD
1010 1020 1030 1040 1050
NEYEPSSNLL EETMYCAKCN KNNIPVYNYY INLKITDSTD SIRASAFANC
1060 1070 1080 1090 1100
AKIIMNGLSA EEYMKLRQEY IMQENIENFD IIEKIKLNEF FFRIKVYMTS
1110 1120 1130 1140
HMDELKKNYT IIDIAPVGKL LIDNCRYLIK SIKNLTSKRD TDHDE
Length:1,145
Mass (Da):134,202
Last modified:May 1, 2000 - v1
Checksum:iE6A2EE89CD37CA6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844503 Genomic DNA. Translation: CAB62873.1.
RefSeqiXP_001351411.1. XM_001351375.1.

Genome annotation databases

EnsemblProtistsiCAB62873; CAB62873; PF3D7_0409600.
GeneDBiPF3D7_0409600.1:pep.
GeneIDi812392.
KEGGipfa:PFD0470c.

Similar proteinsi

Entry informationi

Entry nameiQ9U0J0_PLAF7
AccessioniPrimary (citable) accession number: Q9U0J0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: December 20, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported