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Protein
Submitted name:

F40H3.4a

Gene

fkh-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
F40H3.4aImported
Gene namesi
Name:fkh-8Imported
ORF Names:CELE_F40H3.4Imported, F40H3.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF40H3.4a; CE19865; WBGene00001440; fkh-8.

Subcellular locationi

  1. Nucleus SAAS annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiQ9TZK1. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
T04C9.1Q8MPT26EBI-2315690,EBI-2315635

Protein-protein interaction databases

IntActiQ9TZK1. 1 interaction.
STRINGi6239.F40H3.4.

Structurei

3D structure databases

ProteinModelPortaliQ9TZK1.
SMRiQ9TZK1. Positions 56-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG5025.
GeneTreeiENSGT00780000121840.
HOGENOMiHOG000016962.
PhylomeDBiQ9TZK1.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TZK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLSSSLCQ LNWLIAKGGL NTVQEIEVPE NPNIVGSPVA PAHEGKRRRI
60 70 80 90 100
FDGADKPPYS YSQLIRLAIE DTPDKKCTLA EIYSFIAHNF QFYRENRNSS
110 120 130 140 150
WKNSIRHNLS LNKQFSRIEK TDGDRRGWWV CVDPPAKKPR ILKGSPVRVN
160 170 180 190 200
PIYEHLYHNK QDMPNFTPPP EDPFLSEING NVHELTEHEI RDLNLFESYD
210 220 230 240 250
LNSSFRDVYN QIFEKSTSPN GKKQAAQIDW LKISLEAAGL DYHDEQELQE
260 270 280 290 300
VDTDKLKDYV YNGFPAECDS DVSTPRTDSG RHSSSDSVLS ATLQPVNNDS
310
DDEYDWDKLL
Length:310
Mass (Da):35,520
Last modified:May 1, 2000 - v1
Checksum:iC8582170D1CC8293
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD66154.1.
PIRiT33497.
RefSeqiNP_001254106.1. NM_001267177.1.
UniGeneiCel.15170.

Genome annotation databases

EnsemblMetazoaiF40H3.4a; F40H3.4a; WBGene00001440.
GeneIDi174026.
KEGGicel:CELE_F40H3.4.
UCSCiF40H3.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD66154.1.
PIRiT33497.
RefSeqiNP_001254106.1. NM_001267177.1.
UniGeneiCel.15170.

3D structure databases

ProteinModelPortaliQ9TZK1.
SMRiQ9TZK1. Positions 56-134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9TZK1. 1 interaction.
STRINGi6239.F40H3.4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF40H3.4a; F40H3.4a; WBGene00001440.
GeneIDi174026.
KEGGicel:CELE_F40H3.4.
UCSCiF40H3.4. c. elegans.

Organism-specific databases

CTDi174026.
WormBaseiF40H3.4a; CE19865; WBGene00001440; fkh-8.

Phylogenomic databases

eggNOGiCOG5025.
GeneTreeiENSGT00780000121840.
HOGENOMiHOG000016962.
PhylomeDBiQ9TZK1.

Miscellaneous databases

NextBioi882187.

Gene expression databases

ExpressionAtlasiQ9TZK1. baseline and differential.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ9TZK1_CAEEL
AccessioniPrimary (citable) accession number: Q9TZK1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 29, 2015
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.