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Protein
Submitted name:

PAT-4

Gene

pat-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • integrin binding Source: WormBase
  • protein serine/threonine kinase activity Source: WormBase

GO - Biological processi

  • embryo development ending in birth or egg hatching Source: WormBase
  • integrin-mediated signaling pathway Source: WormBase
  • myofibril assembly Source: WormBase
  • protein phosphorylation Source: WormBase
  • regulation of signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_277854. Cell-extracellular matrix interactions.
REACT_284269. Localization of the PINCH-ILK-PARVIN complex to focal adhesions.

Names & Taxonomyi

Protein namesi
Submitted name:
PAT-4Imported
Gene namesi
Name:pat-4Imported
ORF Names:C29F9.7Imported, CELE_C29F9.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC29F9.7; CE19706; WBGene00003931; pat-4.

Subcellular locationi

GO - Cellular componenti

  • adherens junction Source: WormBase
  • integrin complex Source: WormBase
  • M band Source: WormBase
  • striated muscle dense body Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9TZC4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9TZC4. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
pat-6O167854EBI-1564527,EBI-328106
unc-112Q186855EBI-1564527,EBI-1564809

Protein-protein interaction databases

IntActiQ9TZC4. 4 interactions.
STRINGi6239.C29F9.7.

Structurei

3D structure databases

ProteinModelPortaliQ9TZC4.
SMRiQ9TZC4. Positions 20-465.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 3 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118807.
HOGENOMiHOG000047828.
InParanoidiQ9TZC4.
KOiK06272.
OMAiRDFNEEH.
OrthoDBiEOG7T1RB0.
PhylomeDBiQ9TZC4.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TZC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSTHYHAH KPNVPIIMED VFGWVREGNA FQVRVWLDDH EHDLNVGDDH
60 70 80 90 100
AFSLLHWAAK GGHVAIAEML LSRGARVNST NMGDDTSLHL AAAHGHRQIV
110 120 130 140 150
VKLLSRKADV NATNEHGMTP LHYACFWGYE QIAEDLISCG AAVNVCNKKG
160 170 180 190 200
MTPLDVCQPM CKNTILEIAQ EHGQSPNDRV PFKDTTWKGT KSRTRDATLS
210 220 230 240 250
RYTGVDVSSL NLITKIAESH SGELWRGKWQ GNDIVARILN VQEVTARISR
260 270 280 290 300
DFQTEFPALR IFAHPNICAV LAAANQPPNL VIISQYMPFG SLYNVLHEQS
310 320 330 340 350
SVVIDHGQAV RFALDIARGM SYLHSLDPML LRFYLSSKHV VVDEELTAKL
360 370 380 390 400
SMADTKFSFQ EVGKAYSPAW MSPEALSRAP EDLNIRAADM WSFAILLWEL
410 420 430 440 450
NTREVPFSDL PPMECGMKIA LEGLRVHIPP GIARNMNRLM NICMNEDPGR
460
RPNFDQIIPI LERMIL
Length:466
Mass (Da):52,260
Last modified:May 1, 2000 - v1
Checksum:i0D13147657A0DF11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD66066.1.
PIRiT33574.
RefSeqiNP_497139.1. NM_064738.5.
UniGeneiCel.10243.

Genome annotation databases

EnsemblMetazoaiC29F9.7; C29F9.7; WBGene00003931.
GeneIDi175175.
KEGGicel:CELE_C29F9.7.
UCSCiC29F9.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD66066.1.
PIRiT33574.
RefSeqiNP_497139.1. NM_064738.5.
UniGeneiCel.10243.

3D structure databases

ProteinModelPortaliQ9TZC4.
SMRiQ9TZC4. Positions 20-465.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9TZC4. 4 interactions.
STRINGi6239.C29F9.7.

Proteomic databases

PRIDEiQ9TZC4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC29F9.7; C29F9.7; WBGene00003931.
GeneIDi175175.
KEGGicel:CELE_C29F9.7.
UCSCiC29F9.7. c. elegans.

Organism-specific databases

CTDi175175.
WormBaseiC29F9.7; CE19706; WBGene00003931; pat-4.

Phylogenomic databases

GeneTreeiENSGT00760000118807.
HOGENOMiHOG000047828.
InParanoidiQ9TZC4.
KOiK06272.
OMAiRDFNEEH.
OrthoDBiEOG7T1RB0.
PhylomeDBiQ9TZC4.

Enzyme and pathway databases

ReactomeiREACT_277854. Cell-extracellular matrix interactions.
REACT_284269. Localization of the PINCH-ILK-PARVIN complex to focal adhesions.

Miscellaneous databases

NextBioi887074.
PROiQ9TZC4.

Gene expression databases

ExpressionAtlasiQ9TZC4. baseline and differential.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ9TZC4_CAEEL
AccessioniPrimary (citable) accession number: Q9TZC4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 22, 2015
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.