Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ferritin

Gene

ftn-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.UniRule annotation

Catalytic activityi

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.UniRule annotation

GO - Molecular functioni

  • ferric iron binding Source: InterPro
  • ferroxidase activity Source: UniProtKB-EC
  • identical protein binding Source: IntAct
  • iron ion binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processIron storageUniRule annotationSAAS annotation
LigandIron, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-6798695 Neutrophil degranulation
R-CEL-917937 Iron uptake and transport

Names & Taxonomyi

Protein namesi
Recommended name:
FerritinUniRule annotation (EC:1.16.3.1UniRule annotation)
Gene namesi
Name:ftn-2Imported
ORF Names:CELE_D1037.3Imported, D1037.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiD1037.3 ; CE20622 ; WBGene00001501 ; ftn-2

Subcellular locationi

PTM / Processingi

Proteomic databases

EPDiQ9TYS3
PaxDbiQ9TYS3
PeptideAtlasiQ9TYS3

Expressioni

Gene expression databases

BgeeiWBGene00001501

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-27017N
IntActiQ9TYS3, 8 interactors
MINTiQ9TYS3
STRINGi6239.D1037.3

Structurei

3D structure databases

ProteinModelPortaliQ9TYS3
SMRiQ9TYS3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 155Ferritin-like diironInterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the ferritin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2332 Eukaryota
COG1528 LUCA
GeneTreeiENSGT00760000119129
HOGENOMiHOG000223383
InParanoidiQ9TYS3
KOiK00522
OMAiYVFDKEH
OrthoDBiEOG091G0J20
PhylomeDBiQ9TYS3

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR014034 Ferritin_CS
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS00204 FERRITIN_2, 1 hit
PS50905 FERRITIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9TYS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLARQNYHS EVEAAVNKQI NIELYASYVY LSMSFYFDRD DVALPNIAKF
60 70 80 90 100
FKEQSDEERE HATELMRVQN LRGGRVVLQD IQKPENDEWG TALKAFEAAL
110 120 130 140 150
ALEKFNNESL LKLHSTAGNH NDAHLTDFIE EKYLDEQVKS INEFARMVAN
160 170
LKRVGPGVGE YVFDKEHFSD
Length:170
Mass (Da):19,593
Last modified:May 1, 2000 - v1
Checksum:i7B674B7ED3831B46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CCD68350.1
PIRiT33854
RefSeqiNP_491198.1, NM_058797.5
UniGeneiCel.18344

Genome annotation databases

EnsemblMetazoaiD1037.3.1; D1037.3.1; WBGene00001501
D1037.3.2; D1037.3.2; WBGene00001501
GeneIDi171934
KEGGicel:CELE_D1037.3
UCSCiD1037.3.4 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ9TYS3_CAEEL
AccessioniPrimary (citable) accession number: Q9TYS3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health