Q9TXV2 (Q9TXV2_CAEEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein TAT-2, isoform a EMBL CCD72226.1

Gene names

Name:	tat-2 WormBase H06H21.10a
ORF Names:	H06H21.10 EMBL CCD72226.1

Organism

Caenorhabditis elegans

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	1314 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(Out). SAAS SAAS023299

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023306
Ligand	ATP-binding SAAS SAAS023306 Magnesium SAAS SAAS023299 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS023299
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cation transport Inferred from electronic annotation. Source: InterPro developmental process Inferred from mutant phenotype. Source: WormBase sterol metabolic process Inferred from mutant phenotype. Source: WormBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phospholipid-translocating ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9TXV2 [UniParc]. Last modified June 28, 2011. Version 3. Checksum: D570F3B97F43C726	FASTA	1,314	148,756
	10 20 30 40 50 60 MFSWLPCCSS TSNEKNAPTE RRLRANDREY NAQFKYADNV IKTSKYNIIT FIPQNLFEQF 70 80 90 100 110 120 QRIANFYFLV LMILQFIPQI SSISWYSTAV PLVIVLAFSA IKDGYDDAQR HISDRNVNGR 130 140 150 160 170 180 KSYVVRNGSL CEEDWSNVKV GDVIRMMSNQ FVAADLLLLS TSEPYGVCFI ETMELDGETN 190 200 210 220 230 240 LKNRAAIACT QEMGDDLDGI TRFDGEIICE PPNNKLDKFN GKLIWNNHEY GVNNDNILLR 250 260 270 280 290 300 GCILKNTRWC YGVVVFAGKD TKLMMNSGKT KFKRTSLDRF LNILIVGIVL FLIAMCLICT 310 320 330 340 350 360 ILCAVWEYQT GRYFTIYLPW DDVVPSPEQR GGRQIALIAF LQFFSYIILL NTVVPISLYV 370 380 390 400 410 420 SVEIIRFIHS LWINYDTQMY YENGEKSVPA KAHTTTLNEE LGQVQYVFSD KTGTLTRNIM 430 440 450 460 470 480 TFNKCTINGI SYGDIYDHKG EVIETNDKTK SLDFSWNSAS EPTFKFFDKN LVDATKRQVP 490 500 510 520 530 540 EIDQFWRLLA LCHTVMPERD KGQLVYQAQS PDEHALTSAA RNFGYVFRAR TPQSITIEVM 550 560 570 580 590 600 GNEETHELLA ILDFNNDRKR MSVIVKGPDG KIRLYCKGAD MMIMQRIHPS TSQIMRTSTN 610 620 630 640 650 660 THLADFANIG LRTLCLGYKD LDPAYFSDWD SRVKKASAAM QDRESAVDAL YEEIEKDLIL 670 680 690 700 710 720 IGATAIEDKL QDGVPEAIAR LSEANIKIWV LTGDKTETAI NIAYSCRLLT DETKEIVVVD 730 740 750 760 770 780 GQTDTEVEVQ LKDTRNTFEQ ILALPSPLGG KPRIEIETIH EESEAISSAR SMDRNIVTPD 790 800 810 820 830 840 LKSAEMAEHE SGGVALVING DSLAFALGPR LERTFLEVAC MCNAVICCRV TPLQKAQVVD 850 860 870 880 890 900 LVKRNKKAVT LSIGDGANDV SMIKTAHIGV GISGQEGMQA VLASDYSIGQ FKYLERLLLV 910 920 930 940 950 960 HGRWSYIRMA KFLRYFFYKN FAFTLTNFWY SFFCGYSAQT VFDAVLIACY NLFFTALPVL 970 980 990 1000 1010 1020 AMGSLDQDVD DHYSLRYPKL YLPGQFNLFF NMRIFIYSVL HGMFSSLVIF FIPYGAFYNA 1030 1040 1050 1060 1070 1080 AAASGKDLDD YSALAFTTFT ALVVVVTGQI AFDTSYWTAI SHFVIWGSLV LYFLVCFLLY 1090 1100 1110 1120 1130 1140 EWLPVSWIVK TSSSISYGVA FRTMVTPHFW FSILMVSVVL LLPVMLNRFF WLDTHPSFAD 1150 1160 1170 1180 1190 1200 RLRIRKKMGK KPSAKDDKKT AFKRTAATRR SVRGSLRSGY AFSHSQGFGE LILKGKLFKN 1210 1220 1230 1240 1250 1260 VENLRGKNNS NAKIHPTSDD LQPMLISSVP DDSQGASSIN AMHLPMGTRP QNVPHTLNVN 1270 1280 1290 1300 1310 TDDWSQSSDF RPAYAKEPSP LQGTVIRGDG RSHRNHVYSR ETQVEEQPDV ITRL

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO081529 Genomic DNA. Translation: CCD72226.1.
UniGene	Cel.6173.
3D structure databases
ProteinModelPortal	Q9TXV2.
SMR	Q9TXV2. Positions 668-710, 826-890.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9TXV2.
Proteomic databases
PRIDE	Q9TXV2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	H06H21.10a; H06H21.10a; H06H21.10.
UCSC	H06H21.10b. c. elegans.
Organism-specific databases
WormBase	H06H21.10a; CE45939; WBGene00019166; tat-2.
Phylogenomic databases
OMA	FVANTRW.
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006539. ATPase_P-typ_Plipid-transl. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
Pfam	PF00122. E1-E2_ATPase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01652. ATPase-Plipid. 1 hit. TIGR01494. ATPase_P-type. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9TXV2_CAEEL

Accession

Primary (citable) accession number: Q9TXV2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	June 28, 2011
Last modified:	January 25, 2012
This is version 89 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)