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Protein
Submitted name:

Interleukin-1 receptor type I

Gene
N/A
Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor type IImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei338 – 35922HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 573553Sequence analysisPRO_5004334788Add
BLAST

Proteomic databases

PaxDbiQ9TV71.

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000014347.

Structurei

3D structure databases

ProteinModelPortaliQ9TV71.
SMRiQ9TV71. Positions 21-331.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 110106Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini118 – 21093Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini226 – 328103Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini383 – 541159TIRInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQBC. Eukaryota.
ENOG410Z3W1. LUCA.
HOGENOMiHOG000253916.
HOVERGENiHBG052103.
KOiK04386.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS50104. TIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TV71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLPRLVCF IALLISSLEA DKCEERGEPI VLVSSAYEID VRSCPLNPNE
60 70 80 90 100
SNGTIIWYKN DSETPVSMER DSRIHQYKDK LWFVPAKIED SGHYYCAVRN
110 120 130 140 150
STYCLKVKIT ARFVQHEPDL CYNAQAIFTQ KLPLGEDGLL VCPYLEVFRD
160 170 180 190 200
ENNELPKIQW YKDCQPLLLD NINFIGKTDK LIVANVTEAH KGHYTCHISY
210 220 230 240 250
THLGKQYPIT RVIGLITLDE IRPTKPLIVS PVNETMEVDL GSQVQLICNV
260 270 280 290 300
TGMFTDFVYW RWNGSLIDDS DPVLVEEYKP VENPSLKRRH TLITVLNISA
310 320 330 340 350
VESRFYLYPF TCLAKNSYGR SAAYVQLRQP VPDFQKHVIG IFVLLTVAIT
360 370 380 390 400
CSVFIYKLFK VDLVLWYRDS CYDFRSPKAS DGKTYDAYIL YPKILGEGST
410 420 430 440 450
SNSDIFVFKV LPEVLEKQCG YKLFIYGRDD YVGEDIVEVT NENIKKSRRL
460 470 480 490 500
IIILVRETSG LSWLGSSSEE QIAMYNALVQ DGIKIILLEL EKIQDYEKMP
510 520 530 540 550
ESIKFIKRKH GALRWSGDSR KGPQSAKARF WKNVRYRMPV QRQLPSSKCQ
560 570
LLSPATRPDS KEKLQGEVHV PLG
Length:573
Mass (Da):65,767
Last modified:May 1, 2000 - v1
Checksum:i25703365A89B230B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020338 mRNA. Translation: BAA83730.1.
RefSeqiNP_001075263.2. NM_001081794.2.
UniGeneiEca.12590.

Genome annotation databases

GeneIDi100009699.
KEGGiecb:100009699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020338 mRNA. Translation: BAA83730.1.
RefSeqiNP_001075263.2. NM_001081794.2.
UniGeneiEca.12590.

3D structure databases

ProteinModelPortaliQ9TV71.
SMRiQ9TV71. Positions 21-331.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000014347.

Proteomic databases

PaxDbiQ9TV71.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100009699.
KEGGiecb:100009699.

Organism-specific databases

CTDi3554.

Phylogenomic databases

eggNOGiENOG410IQBC. Eukaryota.
ENOG410Z3W1. LUCA.
HOGENOMiHOG000253916.
HOVERGENiHBG052103.
KOiK04386.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS50104. TIR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9TV71_HORSE
AccessioniPrimary (citable) accession number: Q9TV71
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: January 20, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.