SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9TUM6

- PLIN2_BOVIN

UniProt

Q9TUM6 - PLIN2_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Perilipin-2

Gene
PLIN2, ADFP, ADRP
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May be involved in development and maintenance of adipose tissue By similarity.

Names & Taxonomyi

Protein namesi
Recommended name:
Perilipin-2
Alternative name(s):
Adipophilin
Adipose differentiation-related protein
Short name:
ADRP
Gene namesi
Name:PLIN2
Synonyms:ADFP, ADRP
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 450449Perilipin-2PRO_0000099887Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9TUM6.
PRIDEiQ9TUM6.

Expressioni

Tissue specificityi

Milk lipid globules.

Structurei

3D structure databases

ProteinModelPortaliQ9TUM6.

Family & Domainsi

Sequence similaritiesi

Belongs to the perilipin family.

Phylogenomic databases

eggNOGiNOG68493.
HOGENOMiHOG000033816.
HOVERGENiHBG002935.
InParanoidiQ9TUM6.
KOiK17284.

Family and domain databases

InterProiIPR004279. Perilipin.
[Graphical view]
PANTHERiPTHR14024. PTHR14024. 1 hit.
PfamiPF03036. Perilipin. 1 hit.
[Graphical view]
PIRSFiPIRSF036881. PAT. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9TUM6-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MASVAVEPQL SVVTRVANLP LVSSTYDLVS SAYISRKDQY PYLKSLCEMA    50
EKGMKTITSV AVTSALPIIQ KLEPQIAVAN TYACKGLDRI EEKLPILNQP 100
TNQVVANAKG AMTGAKDAVT TTVTGAKDSV ASTITGVVDR TKGAVTGSVE 150
KTKSVVSGSI NTVLRSRVMQ LMSSGVENAL TKSELLVDQY LPLTKDELEK 200
EAKKVEGFDM VQKPSYYVRL GSLSTKLRSR AYQQALCRVE EAKRKGQETI 250
SQLHSAFNLS ELARKNVHNA NQKIQDAQDK LYLSWLEWKR SIGYDDTDES 300
HCAEHIESRT LAIARNLTQQ LQTMCHTLLS NIQGLPQNIQ DRANHLGVMA 350
GDIYSVFRNA ASFKEVSDGL LASSKGQLQK MKESLDDVMD YLVNNTPLNW 400
LVGPFYPQVT ESESAQAPGT TRRPGRWSRK HPKPVPVSNA EGSQPDDSSS 450
Length:450
Mass (Da):49,368
Last modified:May 1, 2000 - v1
Checksum:iA5026FF11969A885
GO
Isoform 2 (identifier: Q9TUM6-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     402-450: VGPFYPQVTE...EGSQPDDSSS → ALDFSITDFT...EPSQGKMLNN

Note: No experimental confirmation available.

Show »
Length:447
Mass (Da):49,102
Checksum:i9BDC82ECADB0FCEB
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei402 – 45049VGPFY…DDSSS → ALDFSITDFTSETDEIPDII ALEEEDGPNHSHANGPEPSQ GKMLNN in isoform 2. VSP_019867Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti54 – 541M → T in AAI02212. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ011680 mRNA. Translation: CAB53860.1.
BC102211 mRNA. Translation: AAI02212.1.
RefSeqiNP_776405.1. NM_173980.2. [Q9TUM6-1]
UniGeneiBt.2568.

Genome annotation databases

GeneIDi280981.
KEGGibta:280981.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ011680 mRNA. Translation: CAB53860.1 .
BC102211 mRNA. Translation: AAI02212.1 .
RefSeqi NP_776405.1. NM_173980.2. [Q9TUM6-1 ]
UniGenei Bt.2568.

3D structure databases

ProteinModelPortali Q9TUM6.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q9TUM6.
PRIDEi Q9TUM6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 280981.
KEGGi bta:280981.

Organism-specific databases

CTDi 123.

Phylogenomic databases

eggNOGi NOG68493.
HOGENOMi HOG000033816.
HOVERGENi HBG002935.
InParanoidi Q9TUM6.
KOi K17284.

Miscellaneous databases

NextBioi 20805082.

Family and domain databases

InterProi IPR004279. Perilipin.
[Graphical view ]
PANTHERi PTHR14024. PTHR14024. 1 hit.
Pfami PF03036. Perilipin. 1 hit.
[Graphical view ]
PIRSFi PIRSF036881. PAT. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of adipophilin and butyrophilin from bovine milk and characterization of a cDNA encoding adipophilin."
    Nielsen R.L., Andersen M.H., Mabhout P., Berglund L., Petersen T.E., Rasmussen J.T.
    J. Dairy Sci. 82:2543-2549(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Mammary gland.
  2. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiPLIN2_BOVIN
AccessioniPrimary (citable) accession number: Q9TUM6
Secondary accession number(s): Q3T0Y0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi