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Q9TUI5 (MT4_CANFA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Metallothionein-4

Short name=MT-4
Alternative name(s):
Metallothionein-IV
Short name=MT-IV
Gene names
Name:MT4
OrganismCanis familiaris (Dog) (Canis lupus familiaris) [Reference proteome]
Taxonomic identifier9615 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Protein attributes

Sequence length62 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia By similarity.

Sequence similarities

Belongs to the metallothionein superfamily. Type 1 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6262Metallothionein-4
PRO_0000197254

Sites

Metal binding61Divalent metal cation; cluster B By similarity
Metal binding81Divalent metal cation; cluster B By similarity
Metal binding141Divalent metal cation; cluster B By similarity
Metal binding161Divalent metal cation; cluster B By similarity
Metal binding201Divalent metal cation; cluster B By similarity
Metal binding221Divalent metal cation; cluster B By similarity
Metal binding251Divalent metal cation; cluster B By similarity
Metal binding271Divalent metal cation; cluster B By similarity
Metal binding301Divalent metal cation; cluster B By similarity
Metal binding341Divalent metal cation; cluster A By similarity
Metal binding351Divalent metal cation; cluster A By similarity
Metal binding371Divalent metal cation; cluster A By similarity
Metal binding381Divalent metal cation; cluster A By similarity
Metal binding421Divalent metal cation; cluster A By similarity
Metal binding451Divalent metal cation; cluster A By similarity
Metal binding491Divalent metal cation; cluster A By similarity
Metal binding511Divalent metal cation; cluster A By similarity
Metal binding581Divalent metal cation; cluster A By similarity
Metal binding601Divalent metal cation; cluster A By similarity
Metal binding611Divalent metal cation; cluster A By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9TUI5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 2858DA6D17AA3DC9

FASTA626,249
        10         20         30         40         50         60 
MDPGECTCMS GGICICGDNC KCTTCNCKTC RKSCCPCCPP GCAKCAQGCI CKGGSDKCSC 


CA 

« Hide

References

[1]"Molecular cloning and expression of metallothionein-IV."
Kobayashi K., Morita T., Shimada A.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Beagle.
Tissue: Tongue.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB028041 mRNA. Translation: BAA87326.1.
RefSeqNP_001003150.1. NM_001003150.1.
UniGeneCfa.3632.

3D structure databases

ProteinModelPortalQ9TUI5.
SMRQ9TUI5. Positions 32-62.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSCAFT00000014504; ENSCAFP00000013416; ENSCAFG00000009118.
GeneID403769.
KEGGcfa:403769.

Organism-specific databases

CTD84560.

Phylogenomic databases

eggNOGNOG69278.
GeneTreeENSGT00730000111475.
HOGENOMHOG000236262.
InParanoidQ9TUI5.
KOK14741.
OMACTNCNCK.
OrthoDBEOG7G7KSQ.
TreeFamTF336054.

Family and domain databases

Gene3D4.10.10.10. 1 hit.
InterProIPR017854. Metalthion_dom.
IPR023587. Metalthion_dom_vert.
IPR003019. Metalthion_sfam_euk.
IPR000006. Metalthion_vert.
IPR018064. Metalthion_vert_metal_BS.
[Graphical view]
PANTHERPTHR23299. PTHR23299. 1 hit.
PfamPF00131. Metallothio. 1 hit.
[Graphical view]
PRINTSPR00860. MTVERTEBRATE.
SUPFAMSSF57868. SSF57868. 1 hit.
PROSITEPS00203. METALLOTHIONEIN_VRT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20817269.

Entry information

Entry nameMT4_CANFA
AccessionPrimary (citable) accession number: Q9TUI5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Metallothioneins

Classification of metallothioneins and list of entries