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Protein

Protein fosB

Gene

FOSB

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

FosB interacts with Jun proteins enhancing their DNA binding activity.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein fosB
Gene namesi
Name:FOSB
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000764751 – 338Protein fosBAdd BLAST338

Proteomic databases

PaxDbiQ9TUB3

Interactioni

Subunit structurei

Heterodimer.By similarity

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000006628

Structurei

3D structure databases

ProteinModelPortaliQ9TUB3
SMRiQ9TUB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 218bZIPPROSITE-ProRule annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni157 – 182Basic motifPROSITE-ProRule annotationAdd BLAST26
Regioni183 – 211Leucine-zipperPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the bZIP family. Fos subfamily.Curated

Phylogenomic databases

eggNOGiKOG1414 Eukaryota
ENOG4111CH5 LUCA
HOGENOMiHOG000234334
HOVERGENiHBG005743
InParanoidiQ9TUB3
KOiK09029

Family and domain databases

InterProiView protein in InterPro
IPR000837 AP-1
IPR004827 bZIP
IPR029813 FosB
PANTHERiPTHR23351 PTHR23351, 1 hit
PTHR23351:SF3 PTHR23351:SF3, 1 hit
PfamiView protein in Pfam
PF00170 bZIP_1, 1 hit
PRINTSiPR00042 LEUZIPPRFOS
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9TUB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQAFPGDYD SGSRCSSSPS AESQYLSSVD SFGSPPTAAA SQECAGLGEM
60 70 80 90 100
PGSFVPTVTA ITTSQDLQWL VQPTLISSMA QSQGQPLASQ PPAVDPYDMP
110 120 130 140 150
GTSYSTPGMS GYSSGGASGS GGPSTSGTTS GPGPARPARA RLRRPREETL
160 170 180 190 200
TPEEEEKRRV RRERNKLAAA KCRNRRRELT DRLQAETDQL EEEKAELESE
210 220 230 240 250
IAELQKEKER LEFVLVAHKP GCKIPYEEGP GPGPLAEVRD LPGSASTKED
260 270 280 290 300
GFSWLLPPPP APPLPFQTSQ DAAPNLTASL FTHSEVQVLG DPFPVVNPSY
310 320 330
TSSFVLTCPE VSAFAGTQRP SGSDQPTDPL NSPSLLAL
Length:338
Mass (Da):35,924
Last modified:May 1, 2000 - v1
Checksum:iCDD2800870FE197A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF095857 Genomic DNA Translation: AAF01350.1
RefSeqiNP_001013866.1, NM_001013844.1
UniGeneiCfa.23480

Genome annotation databases

GeneIDi484445
KEGGicfa:484445

Similar proteinsi

Entry informationi

Entry nameiFOSB_CANLF
AccessioniPrimary (citable) accession number: Q9TUB3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: May 1, 2000
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health