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Protein

Olfactory receptor 1E1

Gene

OR1E1

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1E1
Gene namesi
Name:OR1E1
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 17

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525ExtracellularSequence analysisAdd
BLAST
Transmembranei26 – 4924Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini50 – 578CytoplasmicSequence analysis
Transmembranei58 – 7922Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini80 – 10021ExtracellularSequence analysisAdd
BLAST
Transmembranei101 – 12020Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini121 – 13919CytoplasmicSequence analysisAdd
BLAST
Transmembranei140 – 15819Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini159 – 19537ExtracellularSequence analysisAdd
BLAST
Transmembranei196 – 21924Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini220 – 23617CytoplasmicSequence analysisAdd
BLAST
Transmembranei237 – 25923Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini260 – 27213ExtracellularSequence analysisAdd
BLAST
Transmembranei273 – 29220Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini293 – 31422CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Olfactory receptor 1E1PRO_0000150427Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...)Sequence analysis
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9TUA9.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014614.

Structurei

3D structure databases

ProteinModelPortaliQ9TUA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J9M4. Eukaryota.
ENOG41113B1. LUCA.
GeneTreeiENSGT00810000125354.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA9.
KOiK04257.
OMAiRVICKRQ.
OrthoDBiEOG7JT6WV.
TreeFamiTF337210.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TUA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMGQNQTSIS DFLLLGLPIQ PEQQNLCYAL FLAMYLTTLL GNLLIIVLIR
60 70 80 90 100
LDSHLHTPMY LFLSNLSFSD LCFSSVTIPK LLQNMQNQDP SIPYADCLTQ
110 120 130 140 150
MYFFLLFGDL ESFLLVAMAY DRYVAICFPL HYTAIMSPML CLSVVALSWV
160 170 180 190 200
LTTFHAMLHT LLMARLCFCA DNVIPHFFCD MSALLKLACS DTRVNEWVIF
210 220 230 240 250
IMGGLILVIP FLLILGSYAR IVSSILKVPS SKGICKALST CGSHLSVVSL
260 270 280 290 300
FYGTVIGLYL CPSANSSTLK DTVMAMIYTV VTPMLNPFIY SLRNRDMKGA
310
LSRVIHQKKT FFSL
Length:314
Mass (Da):35,180
Last modified:May 1, 2000 - v1
Checksum:i7300F67F905173B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101730 Genomic DNA. Translation: AAF03315.1.
RefSeqiNP_001009879.1. NM_001009879.1.
XP_009429824.1. XM_009431549.1.
UniGeneiPtr.6370.
Ptr.6375.

Genome annotation databases

EnsembliENSPTRT00000015796; ENSPTRP00000014614; ENSPTRG00000008564.
GeneIDi468157.
494121.
KEGGiptr:468157.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101730 Genomic DNA. Translation: AAF03315.1.
RefSeqiNP_001009879.1. NM_001009879.1.
XP_009429824.1. XM_009431549.1.
UniGeneiPtr.6370.
Ptr.6375.

3D structure databases

ProteinModelPortaliQ9TUA9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014614.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9TUA9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000015796; ENSPTRP00000014614; ENSPTRG00000008564.
GeneIDi468157.
494121.
KEGGiptr:468157.

Organism-specific databases

CTDi8387.
8388.

Phylogenomic databases

eggNOGiENOG410J9M4. Eukaryota.
ENOG41113B1. LUCA.
GeneTreeiENSGT00810000125354.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA9.
KOiK04257.
OMAiRVICKRQ.
OrthoDBiEOG7JT6WV.
TreeFamiTF337210.

Miscellaneous databases

NextBioi20845856.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenes."
    Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T., Lancet D.
    Genomics 61:24-36(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiOR1E1_PANTR
AccessioniPrimary (citable) accession number: Q9TUA9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: May 1, 2000
Last modified: January 20, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.