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Protein

Olfactory receptor 1A1

Gene

OR1A1

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1A1
Gene namesi
Name:OR1A1
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 17

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 49Helical; Name=1Sequence analysisAdd BLAST24
Topological domaini50 – 57CytoplasmicSequence analysis8
Transmembranei58 – 79Helical; Name=2Sequence analysisAdd BLAST22
Topological domaini80 – 100ExtracellularSequence analysisAdd BLAST21
Transmembranei101 – 120Helical; Name=3Sequence analysisAdd BLAST20
Topological domaini121 – 139CytoplasmicSequence analysisAdd BLAST19
Transmembranei140 – 158Helical; Name=4Sequence analysisAdd BLAST19
Topological domaini159 – 195ExtracellularSequence analysisAdd BLAST37
Transmembranei196 – 218Helical; Name=5Sequence analysisAdd BLAST23
Topological domaini219 – 235CytoplasmicSequence analysisAdd BLAST17
Transmembranei236 – 258Helical; Name=6Sequence analysisAdd BLAST23
Topological domaini259 – 270ExtracellularSequence analysisAdd BLAST12
Transmembranei271 – 290Helical; Name=7Sequence analysisAdd BLAST20
Topological domaini291 – 309CytoplasmicSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001504141 – 309Olfactory receptor 1A1Add BLAST309

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation
Glycosylationi264N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9TUA7.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014611.

Structurei

3D structure databases

ProteinModelPortaliQ9TUA7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J925. Eukaryota.
ENOG41113BM. LUCA.
GeneTreeiENSGT00860000133768.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA7.
KOiK04257.
OMAiDIHFHVK.
OrthoDBiEOG091G0FGP.
TreeFamiTF337210.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TUA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRENNQSSTL EFILLGVTGQ QEQEDFFYIL FLFIYPITLI GNLLIVLAIC
60 70 80 90 100
SDVHLHNPMY FLLANLSLVD IFFSSVTIPK MLANHLLGSK SISFGGCLTQ
110 120 130 140 150
MYFMIALGNT DSYILAAMAY DRAVAISRPL HYTTIMSPRS CIWLIAGSWV
160 170 180 190 200
IGNANALPHT LLTASLSFCG NQEVANFYCD ITPLLKLSCS DIHFHVKMMY
210 220 230 240 250
LGVGIFSVPL LCIIVSYIRV FSTVFQVPST KGVLKAFSTC GSHLTVVSLY
260 270 280 290 300
YGTVMGMYFR PLTNYSLKDA VITVMYTAVT PMLNPFIYSL RNRDVKAALR

KLFNKRISS
Length:309
Mass (Da):34,544
Last modified:May 1, 2000 - v1
Checksum:iED5D7E104DD17634
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101732 Genomic DNA. Translation: AAF03317.1.
RefSeqiNP_001009115.1. NM_001009115.1.
UniGeneiPtr.6394.

Genome annotation databases

EnsembliENSPTRT00000015791; ENSPTRP00000014611; ENSPTRG00000008560.
GeneIDi468149.
KEGGiptr:468149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101732 Genomic DNA. Translation: AAF03317.1.
RefSeqiNP_001009115.1. NM_001009115.1.
UniGeneiPtr.6394.

3D structure databases

ProteinModelPortaliQ9TUA7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014611.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9TUA7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000015791; ENSPTRP00000014611; ENSPTRG00000008560.
GeneIDi468149.
KEGGiptr:468149.

Organism-specific databases

CTDi8383.

Phylogenomic databases

eggNOGiENOG410J925. Eukaryota.
ENOG41113BM. LUCA.
GeneTreeiENSGT00860000133768.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA7.
KOiK04257.
OMAiDIHFHVK.
OrthoDBiEOG091G0FGP.
TreeFamiTF337210.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOR1A1_PANTR
AccessioniPrimary (citable) accession number: Q9TUA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.