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Protein

Olfactory receptor 1E2

Gene

OR1E2

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1E2
Alternative name(s):
Olfactory receptor 1E4
Gene namesi
Name:OR1E2
Synonyms:OR1E4
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525ExtracellularSequence analysisAdd
BLAST
Transmembranei26 – 4924Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini50 – 578CytoplasmicSequence analysis
Transmembranei58 – 7922Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini80 – 10021ExtracellularSequence analysisAdd
BLAST
Transmembranei101 – 12020Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini121 – 13919CytoplasmicSequence analysisAdd
BLAST
Transmembranei140 – 15819Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini159 – 19638ExtracellularSequence analysisAdd
BLAST
Transmembranei197 – 21923Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini220 – 23617CytoplasmicSequence analysisAdd
BLAST
Transmembranei237 – 26024Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini261 – 27212ExtracellularSequence analysisAdd
BLAST
Transmembranei273 – 29220Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini293 – 31422CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Olfactory receptor 1E2PRO_0000150429Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...)Sequence analysis
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation
Glycosylationi265 – 2651N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9TUA2.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014616.

Structurei

3D structure databases

ProteinModelPortaliQ9TUA2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J9M4. Eukaryota.
ENOG41113B1. LUCA.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA2.
KOiK04257.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TUA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMGQNQTSIS DFLLLGLPIQ PEQQNLCYAL FLAMYLTTLL GNLLIIVLIR
60 70 80 90 100
LDSHLHTPMY LFLSNLSFSD LCFSSVTIPK LLQNMQNQDP SIPYADCLTQ
110 120 130 140 150
MHFFLLFGDL ESFLLVAMAY DRYVAICFPL HYTAIMSPML CLSVVALSWV
160 170 180 190 200
LTTFHAMLHT LLMARLCFCA DNVIPHFFCD MSALLKLACS DTRVNEWVIF
210 220 230 240 250
IMGGLIVVIP FLLILGSYAR IVSSILKVPS FKGICKALST CGSHLSVVSL
260 270 280 290 300
FYGTVIGLYL CPSANSSTLK DTVMAMMYTV VTPMLNPFIY SLRNRDMKGA
310
LERVICKRKN PFLL
Length:314
Mass (Da):35,243
Last modified:May 1, 2000 - v1
Checksum:i540D6BA610674E0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101740 Genomic DNA. Translation: AAF03322.1.
RefSeqiNP_001009162.1. NM_001009162.1.
UniGeneiPtr.6375.

Genome annotation databases

GeneIDi494121.
KEGGiptr:494121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101740 Genomic DNA. Translation: AAF03322.1.
RefSeqiNP_001009162.1. NM_001009162.1.
UniGeneiPtr.6375.

3D structure databases

ProteinModelPortaliQ9TUA2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014616.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9TUA2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi494121.
KEGGiptr:494121.

Organism-specific databases

CTDi8388.

Phylogenomic databases

eggNOGiENOG410J9M4. Eukaryota.
ENOG41113B1. LUCA.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TUA2.
KOiK04257.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOR1E2_PANTR
AccessioniPrimary (citable) accession number: Q9TUA2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: May 1, 2000
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.