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Protein

Olfactory receptor 3A3

Gene

OR3A3

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 3A3
Gene namesi
Name:OR3A3
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2828ExtracellularSequence analysisAdd
BLAST
Transmembranei29 – 5224Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini53 – 608CytoplasmicSequence analysis
Transmembranei61 – 8222Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini83 – 10321ExtracellularSequence analysisAdd
BLAST
Transmembranei104 – 12320Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini124 – 14320CytoplasmicSequence analysisAdd
BLAST
Transmembranei144 – 16118Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini162 – 19938ExtracellularSequence analysisAdd
BLAST
Transmembranei200 – 22223Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini223 – 23917CytoplasmicSequence analysisAdd
BLAST
Transmembranei240 – 26223Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini263 – 27513ExtracellularSequence analysisAdd
BLAST
Transmembranei276 – 29520Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini296 – 31520CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315Olfactory receptor 3A3PRO_0000150521Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi8 – 81N-linked (GlcNAc...)Sequence analysis
Disulfide bondi100 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9TUA0.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014615.

Structurei

3D structure databases

ProteinModelPortaliQ9TUA0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000041364.
HOVERGENiHBG017625.
InParanoidiQ9TUA0.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TUA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESEAGTNRT AVAEFMLLGL VQTEEMQSVI FVLLLFAYLV TTGGNLSILA
60 70 80 90 100
AILVEPKLHT PMYFFLGNLS VLDVGCITVT VPAMLGRLLS HKSTISYDAC
110 120 130 140 150
LSQLFFFHLL AGMDCFLLTA MAYDRFLAIC RPLTYSTHMN QRVQRMLVAV
160 170 180 190 200
SWTCAFTNAL THTIALTTLN FCGPSVINHF YCDLPQLFQL SCSSTQLNEL
210 220 230 240 250
LLFVAAAVMA VAPLVFISVS YAHVVAAVLQ IHSAEGRKKA FSTCGSHLTV
260 270 280 290 300
VGIFYGTGVF SYMRLGSVES SDKDKGVGVF MTVINPMLNP LIYSLRNTDV
310
QGALCQLLVV KRSLT
Length:315
Mass (Da):34,444
Last modified:May 1, 2000 - v1
Checksum:i902C5BC3C3E3A293
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101742 Genomic DNA. Translation: AAF03324.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101742 Genomic DNA. Translation: AAF03324.1.

3D structure databases

ProteinModelPortaliQ9TUA0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014615.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9TUA0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000041364.
HOVERGENiHBG017625.
InParanoidiQ9TUA0.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenes."
    Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T., Lancet D.
    Genomics 61:24-36(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiOR3A3_PANTR
AccessioniPrimary (citable) accession number: Q9TUA0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: May 1, 2000
Last modified: July 6, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.