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Protein

Olfactory receptor 3A2

Gene

OR3A2

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 3A2
Gene namesi
Name:OR3A2
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929ExtracellularSequence analysisAdd
BLAST
Transmembranei30 – 5223Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini53 – 608CytoplasmicSequence analysis
Transmembranei61 – 8222Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini83 – 10321ExtracellularSequence analysisAdd
BLAST
Transmembranei104 – 12320Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini124 – 14320CytoplasmicSequence analysisAdd
BLAST
Transmembranei144 – 16118Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini162 – 19938ExtracellularSequence analysisAdd
BLAST
Transmembranei200 – 22324Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini224 – 24017CytoplasmicSequence analysisAdd
BLAST
Transmembranei241 – 26424Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini265 – 27511ExtracellularSequence analysisAdd
BLAST
Transmembranei276 – 29520Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini296 – 31520CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315Olfactory receptor 3A2PRO_0000150519Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi8 – 81N-linked (GlcNAc...)Sequence analysis
Disulfide bondi100 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9TU97.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000054937.

Structurei

3D structure databases

ProteinModelPortaliQ9TU97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IKVP. Eukaryota.
ENOG411141Z. LUCA.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TU97.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TU97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPEAGTNRT AVAEFILLGL VQTEEMQPVV FVLFLFAYLV TIGGNLSILA
60 70 80 90 100
AILVEPKLHA PMYFFLGNLS VLDVGCITVT VPAMLGRLLS HKSTISYDAC
110 120 130 140 150
LSQLFFFHLL AGMDCFLLTA MAYDRFLAIC WPLTYSTRMS QTVQRMLVAA
160 170 180 190 200
SWACAFTNAL THTVAMSTLN FCGPNEVNHF YCDLPQLFQL SCSSTQLNEL
210 220 230 240 250
LLFAVGFIMA GTPLVLIITS YSHVAAAVLR IRSVEGWKKA FSTCGSHLTV
260 270 280 290 300
VCLFFGTGIF NYMRLGSEEA SDKDKGVGVF NTVINPMLNP LIYSLRNPDV
310
QGALWRIFLG RRSLT
Length:315
Mass (Da):34,750
Last modified:May 1, 2000 - v1
Checksum:i61CE72577F296C6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101746 Genomic DNA. Translation: AAF03327.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101746 Genomic DNA. Translation: AAF03327.1.

3D structure databases

ProteinModelPortaliQ9TU97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000054937.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9TU97.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IKVP. Eukaryota.
ENOG411141Z. LUCA.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ9TU97.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenes."
    Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T., Lancet D.
    Genomics 61:24-36(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiOR3A2_PANTR
AccessioniPrimary (citable) accession number: Q9TU97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: May 1, 2000
Last modified: February 17, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.