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Q9TTS6 (CCL11_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eotaxin
Alternative name(s):
C-C motif chemokine 11
Small-inducible cytokine A11
Gene names
Name:CCL11
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length97 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Attracts eosinophils in vitro but is not responsible for eosinophilia in the ovary. Ref.1

Subcellular location

Secreted.

Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 9774Eotaxin
PRO_0000244408

Amino acid modifications

Disulfide bond32 ↔ 57 By similarity
Disulfide bond33 ↔ 73 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9TTS6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 9E65F23E1DDEB743

FASTA9710,965
        10         20         30         40         50         60 
MKVSAVLLCL LLTATLCSIQ VLAQPASIPT ICCFNMSKKK ISIQRLQSYR KITSSKCPQK 

        70         80         90 
AVIFNTKQNK KICVDPQEKW VQNAMEYLNQ KSQTLKS 

« Hide

References

« Hide 'large scale' references
[1]"Bovine eotaxin (CCL11) -- an unusual member of the eotaxin group --attracts eosinophils in vitro but is not responsible for eosinophilia in the ovary."
Vogel B., Klinder A., Sittig D., Aust G.
Vet. Immunol. Immunopathol. 107:67-77(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
[2]NIH - Mammalian Gene Collection (MGC) project
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Uterus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ132003 mRNA. Translation: CAB61617.1.
BC114735 mRNA. Translation: AAI14736.1.
RefSeqNP_991342.1. NM_205773.2.
UniGeneBt.24326.

3D structure databases

ProteinModelPortalQ9TTS6.
SMRQ9TTS6. Positions 25-96.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9TTS6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000005406; ENSBTAP00000005406; ENSBTAG00000004129.
GeneID404072.
KEGGbta:404072.

Organism-specific databases

CTD6356.

Phylogenomic databases

GeneTreeENSGT00730000110714.
HOGENOMHOG000036686.
HOVERGENHBG017871.
InParanoidQ9TTS6.
KOK16597.
OMAGSKCPQK.
OrthoDBEOG7C5MC2.
TreeFamTF334888.

Family and domain databases

InterProIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamPF00048. IL8. 1 hit.
[Graphical view]
SMARTSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMSSF54117. SSF54117. 1 hit.
PROSITEPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20817531.

Entry information

Entry nameCCL11_BOVIN
AccessionPrimary (citable) accession number: Q9TTS6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families