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Q9TP17

- Q9TP17_MOUSE

UniProt

Q9TP17 - Q9TP17_MOUSE

Protein
Submitted name:

MHC class II antigen beta chain

Gene

Rmcs1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 3 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class II antigen beta chainImported
    Gene namesi
    Name:Rmcs1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IIUniRule annotationSAAS annotation

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1717 PotentialImportedAdd
    BLAST
    Chaini18 – 255238 PotentialImportedPRO_5000053360Add
    BLAST

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ9TP17.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000041008.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9TP17.
    SMRiQ9TP17. Positions 19-208.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

    Keywords - Domaini

    SignalImported, Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG012730.
    InParanoidiQ9TP17.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.10.320.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00969. MHC_II_beta. 1 hit.
    [Graphical view]
    ProDomiPD000328. MHC_II_b_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00407. IGc1. 1 hit.
    SM00921. MHC_II_beta. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9TP17-1 [UniParc]FASTAAdd to Basket

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    MHARAAASVM DICRIRLGDS ERHFVYQFMG ECYFTNGTQR IRYVTRYIYN    50
    REEYVRYDSD VGEHRAVTEL GRPDAEYWNS QPEILERTRA ELDTVCRHNY 100
    EGPETHTSLR RLEQPNVVIS LSRTEALNHH NTLVCSVTDF YPAKIKVRWF 150
    RNGQEETVGV SSTQLIRNGD WTFQVLVMLE MTPRRGEVYT CHVEHPSLKS 200
    PITVEWRAQS ESAWSKMLSG IGGCVLGVIF LGLGLFIRHR SQKGPRGPPP 250
    AGLLQ 255
    Length:255
    Mass (Da):29,345
    Last modified:October 17, 2006 - v3
    Checksum:iF4C1055554BCFBA5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF015280 Genomic DNA. Translation: AAF21604.3.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF015280 Genomic DNA. Translation: AAF21604.3 .

    3D structure databases

    ProteinModelPortali Q9TP17.
    SMRi Q9TP17. Positions 19-208.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000041008.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG012730.
    InParanoidi Q9TP17.

    Gene expression databases

    Genevestigatori Q9TP17.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.10.320.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00969. MHC_II_beta. 1 hit.
    [Graphical view ]
    ProDomi PD000328. MHC_II_b_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00407. IGc1. 1 hit.
    SM00921. MHC_II_beta. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Hidden variables: unstable Abeta chain genes encoding antigen recognition structures in tumor survivors."
      Liu Y., McMinimy D.L., Savinov A.Y., Johnson K.A., Kremlev S.G., Chapoval A.I., Egorov I.K.
      Mol. Immunol. 37:1091-1110(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TailImported.
    2. "Cloning and expression of mouse Rmcs1, Rmcs2 and Rmcs5 genes: a candidate immune suppression complex."
      Savinov A.Y., Liu Y., McMinimy D.L., Johnson K.A., Egorov I.K.
      Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TailImported.

    Entry informationi

    Entry nameiQ9TP17_MOUSE
    AccessioniPrimary (citable) accession number: Q9TP17
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 93 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)