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Q9TLS3 (ODPB_CYACA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismCyanidium caldarium
Taxonomic identifier2771 [NCBI]
Taxonomic lineageEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidium

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 327327Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280107

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9TLS3 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 0697A6E73817EFF2

FASTA32735,946
        10         20         30         40         50         60 
MSMMFLYEAL RAAIDEEMGK DSNVFIVGED VGHYGGSYKV TKDLHVKYGD LRVLDAPIAE 

        70         80         90        100        110        120 
NSFTGMAIGA AMTGLRPIVE GMNMGFMLLA FNQISNNLSM LQYTSGGNFN IPVVIRGPGG 

       130        140        150        160        170        180 
IGKQLAAEHS QRLESCFQSI PGLQIVACST AYNAKGLLKS AIIEKKPILF LEHVLLYNLK 

       190        200        210        220        230        240 
GFVPDEEYYL PLDKAEVVRS GSDVTIVTYS RMRYHVLAAV EKLVLNGQDP EIIDLISLKP 

       250        260        270        280        290        300 
LDLHTISKSI KKTHKIVIVE ECAQTGGIAA ELISLINTYL YDELDSPAVR LSSKDVPIPY 

       310        320 
NGNLEKSTLI QPDQIVDVVT NLLQYKT 

« Hide

References

[1]"The structure and gene repertoire of an ancient red algal plastid genome."
Gloeckner G., Rosenthal A., Valentin K.-U.
J. Mol. Evol. 51:382-390(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RK-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF022186 Genomic DNA. Translation: AAF12898.1.
RefSeqNP_045196.1. NC_001840.1.

3D structure databases

ProteinModelPortalQ9TLS3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID800229.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
3.40.50.970. 1 hit.
InterProIPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52518. SSF52518. 1 hit.
SSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_CYACA
AccessionPrimary (citable) accession number: Q9TLS3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)