Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9TLS3

- ODPB_CYACA

UniProt

Q9TLS3 - ODPB_CYACA

Protein

Pyruvate dehydrogenase E1 component subunit beta

Gene

pdhB

Organism
Cyanidium caldarium
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.By similarity

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei60 – 601Thiamine pyrophosphateBy similarity

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Pyruvate, Thiamine pyrophosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 component subunit beta (EC:1.2.4.1)
    Gene namesi
    Name:pdhB
    Synonyms:odpB
    Encoded oniPlastid; Chloroplast
    OrganismiCyanidium caldarium
    Taxonomic identifieri2771 [NCBI]
    Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidium

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 327327Pyruvate dehydrogenase E1 component subunit betaPRO_0000280107Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta chain.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9TLS3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProiIPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view]
    PfamiPF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view]
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9TLS3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSMMFLYEAL RAAIDEEMGK DSNVFIVGED VGHYGGSYKV TKDLHVKYGD    50
    LRVLDAPIAE NSFTGMAIGA AMTGLRPIVE GMNMGFMLLA FNQISNNLSM 100
    LQYTSGGNFN IPVVIRGPGG IGKQLAAEHS QRLESCFQSI PGLQIVACST 150
    AYNAKGLLKS AIIEKKPILF LEHVLLYNLK GFVPDEEYYL PLDKAEVVRS 200
    GSDVTIVTYS RMRYHVLAAV EKLVLNGQDP EIIDLISLKP LDLHTISKSI 250
    KKTHKIVIVE ECAQTGGIAA ELISLINTYL YDELDSPAVR LSSKDVPIPY 300
    NGNLEKSTLI QPDQIVDVVT NLLQYKT 327
    Length:327
    Mass (Da):35,946
    Last modified:May 1, 2000 - v1
    Checksum:i0697A6E73817EFF2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF022186 Genomic DNA. Translation: AAF12898.1.
    RefSeqiNP_045196.1. NC_001840.1.

    Genome annotation databases

    GeneIDi800229.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF022186 Genomic DNA. Translation: AAF12898.1 .
    RefSeqi NP_045196.1. NC_001840.1.

    3D structure databases

    ProteinModelPortali Q9TLS3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 800229.

    Family and domain databases

    Gene3Di 3.40.50.920. 1 hit.
    3.40.50.970. 1 hit.
    InterProi IPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005475. Transketolase-like_Pyr-bd.
    IPR005476. Transketolase_C.
    [Graphical view ]
    Pfami PF02779. Transket_pyr. 1 hit.
    PF02780. Transketolase_C. 1 hit.
    [Graphical view ]
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 1 hit.
    SSF52922. SSF52922. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The structure and gene repertoire of an ancient red algal plastid genome."
      Gloeckner G., Rosenthal A., Valentin K.-U.
      J. Mol. Evol. 51:382-390(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RK-1.

    Entry informationi

    Entry nameiODPB_CYACA
    AccessioniPrimary (citable) accession number: Q9TLS3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 6, 2007
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)