Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9TC96 (NDUS2_NEPOL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2

EC=1.6.5.3
EC=1.6.99.3
Alternative name(s):
NADH dehydrogenase subunit 7
Gene names
Name:NAD7
Encoded onMitochondrion
OrganismNephroselmis olivacea (Green alga)
Taxonomic identifier31312 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeChlorophytaNephroselmidophyceaeNephroselmis

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme By similarity. HAMAP-Rule MF_01358

Catalytic activity

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out). HAMAP-Rule MF_01358

NADH + acceptor = NAD+ + reduced acceptor. HAMAP-Rule MF_01358

Cofactor

Binds 1 4Fe-4S cluster By similarity. HAMAP-Rule MF_01358

Subunit structure

Complex I is composed of about 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme By similarity.

Subcellular location

Mitochondrion HAMAP-Rule MF_01358.

Sequence similarities

Belongs to the complex I 49 kDa subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 HAMAP-Rule MF_01358
PRO_0000118584

Sites

Metal binding2611Iron-sulfur (4Fe-4S) Potential
Metal binding2671Iron-sulfur (4Fe-4S) Potential
Metal binding2821Iron-sulfur (4Fe-4S) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9TC96 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: BCBD8FE4AACB08EB

FASTA39845,476
        10         20         30         40         50         60 
MAIEHASSIK KVKNFTLNFG PQHPAAHGVL RLVLELNGEV VARADPHIGL LHRGTEKLIE 

        70         80         90        100        110        120 
YKTYTQALPY FDRLDYVSMM CQEHAYSLAV EKLLHCEVPE RAQYIRVLFS EITRILNHLL 

       130        140        150        160        170        180 
ALTTHAMDVG ALTPFLWAFE EREKLIEFYE RVSGSRMHAA YIRPGGVACD LPANLCEDIY 

       190        200        210        220        230        240 
LFCQQFASRI DEMEEMLTNN RIWKQRLVDI GIVTAENAFA WGFSGVLLRG SGVAWDLRKT 

       250        260        270        280        290        300 
QPYDVYNRMI FDVPVGTQGD CYDRYLCRVE EMRQSIHIIM QCLNQLPKGM IKADDKKITP 

       310        320        330        340        350        360 
PSRSQMKQSM ESLIHHFKLF TEGYTVPNSE TYTSVEAPKG EFGVYLVSNG TNRPYRCKIR 

       370        380        390 
APGFLHLQGL DMMSKNHMLA DVVTIIGTQD IVFGEVDR 

« Hide

References

[1]"The complete mitochondrial DNA sequences of Nephroselmis olivacea and Pedinomonas minor: two radically different evolutionary patterns within the green algae."
Turmel M., Lemieux C., Burger G., Lang B.F., Otis C., Plante I., Gray M.W.
Plant Cell 11:1717-1730(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: NIES-484.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF110138 Genomic DNA. Translation: AAF03201.1.
RefSeqYP_665674.1. NC_008239.1.

3D structure databases

ProteinModelPortalQ9TC96.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4178038.

Family and domain databases

Gene3D1.10.645.10. 2 hits.
HAMAPMF_01358. NDH1_NuoD.
InterProIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMSSF56762. SSF56762. 1 hit.
TIGRFAMsTIGR01962. NuoD. 1 hit.
PROSITEPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNDUS2_NEPOL
AccessionPrimary (citable) accession number: Q9TC96
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families