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Q9TAJ7

- NDUS2_CAFRO

UniProt

Q9TAJ7 - NDUS2_CAFRO

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Protein

NADH-ubiquinone oxidoreductase 49 kDa subunit

Gene
NAD7
Organism
Cafeteria roenbergensis
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme By similarity.UniRule annotation

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation
NADH + acceptor = NAD+ + reduced acceptor.UniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
  3. quinone binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase 49 kDa subunit (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
NADH dehydrogenase subunit 7
Gene namesi
Name:NAD7
Encoded oniMitochondrion
OrganismiCafeteria roenbergensis
Taxonomic identifieri33653 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesBicosoecidaCafeteriaceaeCafeteria

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-SubCell
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398NADH-ubiquinone oxidoreductase 49 kDa subunitUniRule annotationPRO_0000118588Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9TAJ7.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.645.10. 2 hits.
HAMAPiMF_01358. NDH1_NuoD.
InterProiIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamiPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMiSSF56762. SSF56762. 1 hit.
TIGRFAMsiTIGR01962. NuoD. 1 hit.
PROSITEiPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9TAJ7-1 [UniParc]FASTAAdd to Basket

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MFIKRKLKET EIKDFTLNFG PQHPAAHGVL RLILELNGET IKNADPHIGL    50
LHRGTEKLIE NRNYLQALPY FDRLDYVSMM VQEHAYSLAV ERLYGINIPQ 100
RAQWIRVLFS EITRILNHLL AIGCHSMDVG AMTPLLWGFE EREKLMEFYE 150
RVSGARMHAS YIRPGGVAQD LPSGFVEDVY SFILDFSVRL DEIEELLTNN 200
RIWKQRLVNV GIVTAKQAIQ NGFSGVLLRS TGIPWDLRRS QPYEIYDKVP 250
FRIPVGTRGD CYDRYLIRMQ EMRQSLRIMM ACLKYLPGGS IKSDDKKFVP 300
PLRWEMKNSM ESVIHHFKYF TEGFKVPAGQ TYAAVEAPKG EMGVFLISDG 350
SNQPFRCKIK APGFFHLQNL PEMTKHHMIA DVVTIIGTQD IVFGEVDR 398
Length:398
Mass (Da):45,813
Last modified:May 1, 2000 - v1
Checksum:i1BDDAF669C91404E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193903 Genomic DNA. Translation: AAF05789.1.
RefSeqiNP_051138.1. NC_000946.1.

Genome annotation databases

GeneIDi800841.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193903 Genomic DNA. Translation: AAF05789.1 .
RefSeqi NP_051138.1. NC_000946.1.

3D structure databases

ProteinModelPortali Q9TAJ7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 800841.

Family and domain databases

Gene3Di 1.10.645.10. 2 hits.
HAMAPi MF_01358. NDH1_NuoD.
InterProi IPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view ]
Pfami PF00346. Complex1_49kDa. 1 hit.
[Graphical view ]
SUPFAMi SSF56762. SSF56762. 1 hit.
TIGRFAMsi TIGR01962. NuoD. 1 hit.
PROSITEi PS00535. COMPLEX1_49K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The mitochondrial genome of Cafeteria roenbergensis."
    Burger G.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiNDUS2_CAFRO
AccessioniPrimary (citable) accession number: Q9TAJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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