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Q9T1X2 (LYS_BPMU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Muramidase
Gene names
Name:lys
Synonyms:22
OrganismEnterobacteria phage Mu (Bacteriophage Mu) [Reference proteome]
Taxonomic identifier10677 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeMulikevirus
Virus hostEnterobacteriaceae [TaxID: 543]

Protein attributes

Sequence length171 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 171171Lysozyme
PRO_0000218096

Sites

Active site371Proton donor By similarity
Active site461Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9T1X2 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 9F53C6ADF47D4789

FASTA17118,884
        10         20         30         40         50         60 
MAGIPKKLKA ALLAVTIAGG GVGGYQEMTR QSLIHLENIA YMPYRDIAGV LTVCVGHTGP 

        70         80         90        100        110        120 
DIEMRRYSHA ECMALLDSDL KPVYAAIDRL VRVPLTPYQK TALATFIFNT GVTAFSKSTL 

       130        140        150        160        170 
LKKLNAGDYA GARDQMARWV FAAGHKWKGL MNRREVEMAI WNIRGADDLR Q 

« Hide

References

[1]"Bacteriophage Mu genome sequence: analysis and comparison with Mu-like prophages in Haemophilus, Neisseria and Deinococcus."
Morgan G.J., Hatfull G.F., Casjens S., Hendrix R.W.
J. Mol. Biol. 317:337-359(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF083977 Genomic DNA. Translation: AAF01099.1.
RefSeqNP_050626.1. NC_000929.1.

3D structure databases

ProteinModelPortalQ9T1X2.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2636261.

Phylogenomic databases

ProtClustDBCLSP2743389.

Family and domain databases

Gene3D1.10.530.40. 1 hit.
InterProIPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLYS_BPMU
AccessionPrimary (citable) accession number: Q9T1X2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: October 16, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries